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S-15535

S-15535 is a phenylpiperazine drug which is a potent and highly selective 5-HT1A receptor ligand that acts as an agonist and antagonist (weak partial agonist) at the presynaptic and postsynaptic 5-HT1A receptors, respectively. [1]

12 relations: Agonist, Anxiolytic, Binding selectivity, Chemical synapse, Drug, Ligand (biochemistry), Partial agonist, Phenylpiperazine, Potency (pharmacology), Receptor (biochemistry), Receptor antagonist, 5-HT1A receptor.

Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Anxiolytic

An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.

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Binding selectivity

Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

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Chemical synapse

Chemical synapses are specialized junctions through which neurons signal to each other and to non-neuronal cells such as those in muscles or glands.

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Drug

A drug is, in the broadest of terms, a chemical substance that has known biological effects on humans or other animals.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

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Phenylpiperazine

1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule usually found embedded within the plasma membrane surface of a cell that receives chemical signals from outside the cell.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens agonist-mediated responses rather than provoking a biological response itself upon binding to a receptor.

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5-HT1A receptor

The 5-HT1A receptor is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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Redirects here:

S 15535, S-15,535, S15535.

References

[1] https://en.wikipedia.org/wiki/S-15535

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