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21 relations: Biomolecular structure, Cajal body, Conserved sequence, Eukaryote, Gene, Isomerization, Molecular and Cellular Biology, Nucleic Acids Research, Pseudouridine, RNA polymerase II, Small Cajal body-specific RNA, Small nuclear RNA, Small nucleolar RNA, Spliceosome, The EMBO Journal, U1 spliceosomal RNA, U12 minor spliceosomal RNA, U2 spliceosomal RNA, U4 spliceosomal RNA, U5 spliceosomal RNA, Uridine.
Biomolecular structure
Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to its function.
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Cajal body
Cajal bodies (CBs) also coiled bodies, are spherical sub-organelles of 0.3–1.0 µm in diameter found in the nucleus of proliferative cells like embryonic cells and tumor cells, or metabolically active cells like neurons.
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Conserved sequence
In evolutionary biology, conserved sequences are similar or identical sequences in nucleic acids (DNA and RNA) or proteins across species (orthologous sequences) or within a genome (paralogous sequences).
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Isomerization
In chemistry isomerization (also isomerisation) is the process by which one molecule is transformed into another molecule which has exactly the same atoms, but the atoms have a different arrangement e.g. A-B-C → B-A-C (these related molecules are known as isomers). In some molecules and under some conditions, isomerization occurs spontaneously.
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Molecular and Cellular Biology
Molecular and Cellular Biology is a bimonthly peer-reviewed scientific journal published by the American Society for Microbiology.
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Nucleic Acids Research
Nucleic Acids Research is an open-access peer-reviewed scientific journal published by Oxford University Press.
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Pseudouridine
Pseudouridine (abbreviated by the Greek letter psi- Ψ or the letter Q) is an isomer of the nucleoside uridine in which the uracil is attached via a carbon-carbon instead of a nitrogen-carbon glycosidic bond.
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RNA polymerase II
RNA polymerase II (RNAP II and Pol II) is a multiprotein complex.
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Small Cajal body-specific RNA
Small Cajal body-specific RNAs (scaRNAs) are a class of small nucleolar RNAs (snoRNAs) that specifically localise to the Cajal body, a nuclear organelle (cellular sub-organelle) involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs or snurps).
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Small nuclear RNA
Small nuclear ribonucleic acid (snRNA), also commonly referred to as U-RNA, is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic cells.
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Small nucleolar RNA
Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs.
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Spliceosome
A spliceosome is a large and complex molecular machine found primarily within the splicing speckles of the cell nucleus of eukaryotic cells.
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The EMBO Journal
The EMBO Journal is a peer-reviewed scientific journal focusing on full-length papers describing original research of general interest in molecular biology and related areas.
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U1 spliceosomal RNA
U1 spliceosomal RNA is the small nuclear RNA (snRNA) component of U1 snRNP (small nuclear ribonucleoprotein), an RNA-protein complex that combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs.
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U12 minor spliceosomal RNA
U12 minor spliceosomal RNA is formed from U12 small nuclear (snRNA), together with U4atac/U6atac, U5, and U11 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns.
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U2 spliceosomal RNA
U2 spliceosomal snRNAs are a species of small nuclear RNA (snRNA) molecules found in the major spliceosomal (Sm) machinery of virtually all-eukaryotic organisms.
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U4 spliceosomal RNA
The U4 small nuclear Ribo-Nucleic Acid (U4 snRNA) is a non-coding RNA component of the major or U2-dependent spliceosome – a eukaryotic molecular machine involved in the splicing of pre-messenger RNA (pre-mRNA).
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U5 spliceosomal RNA
U5 RNA is a non-coding RNA that is a component of both types of known spliceosome.
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Uridine
Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, a ribofuranose) via a β-N1-glycosidic bond.
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References
[1] https://en.wikipedia.org/wiki/Small_Cajal_body_specific_RNA_23
