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Sensitization

Index Sensitization

Sensitization is a non-associative learning process in which repeated administration of a stimulus results in the progressive amplification of a response. [1]

32 relations: Addiction, AMPA receptor, Amygdala, Aplysia, Behavioral addiction, Chemical synapse, Dopamine, Drug class, Drug tolerance, Epileptic seizure, Eric Kandel, Fibromyalgia, Hippocampus, Kindling (sedative–hypnotic withdrawal), Learning, Limbic system, Long-term potentiation, Mesolimbic pathway, Mood disorder, Multiple chemical sensitivity, Neuroplasticity, Nobel Prize in Physiology or Medicine, Nociceptor, Panic attack, Posterior grey column, Posttraumatic stress disorder, Reverse tolerance, Reward system, Spinal cord, Stimulation, Synaptic plasticity, Temporal lobe epilepsy.

Addiction

Addiction is a brain disorder characterized by compulsive engagement in rewarding stimuli despite adverse consequences.

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AMPA receptor

The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS).

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Amygdala

The amygdala (plural: amygdalae; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'Almond', 'tonsil') is one of two almond-shaped groups of nuclei located deep and medially within the temporal lobes of the brain in complex vertebrates, including humans.

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Aplysia

Aplysia is a genus of medium-sized to extremely large sea slugs, specifically sea hares, which are one clade of large sea slugs, marine gastropod mollusks.

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Behavioral addiction

Behavioral addiction is a form of addiction that involves a compulsion to engage in a rewarding non-drug-related behavior – sometimes called a natural reward – despite any negative consequences to the person's physical, mental, social or financial well-being.

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Chemical synapse

Chemical synapses are biological junctions through which neurons' signals can be exchanged to each other and to non-neuronal cells such as those in muscles or glands.

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Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

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Drug class

A drug class is a set of medications that have similar chemical structures, the same mechanism of action (i.e., bind to the same biological target), a related mode of action, and/or are used to treat the same disease.

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Drug tolerance

Drug tolerance is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use.

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Epileptic seizure

An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

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Eric Kandel

Eric Richard Kandel (born November 7, 1929) is an Austrian-American neuroscientist and a University Professor of biochemistry and biophysics at the College of Physicians and Surgeons at Columbia University.

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Fibromyalgia

Fibromyalgia (FM) is a medical condition characterised by chronic widespread pain and a heightened pain response to pressure.

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Hippocampus

The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.

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Kindling (sedative–hypnotic withdrawal)

Kindling due to substance withdrawal refers to the neurological condition which results from repeated withdrawal episodes from sedative–hypnotic drugs such as alcohol and benzodiazepines.

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Learning

Learning is the process of acquiring new or modifying existing knowledge, behaviors, skills, values, or preferences.

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Limbic system

The limbic system is a set of brain structures located on both sides of the thalamus, immediately beneath the cerebrum.

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Long-term potentiation

In neuroscience, long-term potentiation (LTP) is a persistent strengthening of synapses based on recent patterns of activity.

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Mesolimbic pathway

The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain.

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Mood disorder

Mood disorder, also known as mood (affective) disorders, is a group of conditions where a disturbance in the person's mood is the main underlying feature.

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Multiple chemical sensitivity

Multiple chemical sensitivity (MCS), also known as idiopathic environmental intolerances (IEI), is a disputed chronic condition characterized by symptoms that the affected person attributes to low-level exposures to commonly used chemicals.

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Neuroplasticity

Neuroplasticity, also known as brain plasticity and neural plasticity, is the ability of the brain to change throughout an individual's life, e.g., brain activity associated with a given function can be transferred to a different location, the proportion of grey matter can change, and synapses may strengthen or weaken over time.

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Nobel Prize in Physiology or Medicine

The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin), administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the fields of life sciences and medicine.

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Nociceptor

A nociceptor is a sensory neuron that responds to damaging or potentially damaging stimuli by sending “possible threat” signals to the spinal cord and the brain.

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Panic attack

Panic attacks are sudden periods of intense fear that may include palpitations, sweating, shaking, shortness of breath, numbness, or a feeling that something bad is going to happen.

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Posterior grey column

The posterior grey column (posterior cornu, dorsal horn, spinal dorsal horn posterior horn) of the spinal cord is one of the three grey columns of the spinal cord.

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Posttraumatic stress disorder

Posttraumatic stress disorder (PTSD)Acceptable variants of this term exist; see the Terminology section in this article.

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Reverse tolerance

Reverse tolerance or drug sensitization is a pharmacological concept describing subjects' increased reaction (positive or negative) to a drug following its repeated use.

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Reward system

The reward system is a group of neural structures responsible for incentive salience (i.e., motivation and "wanting", desire, or craving for a reward), associative learning (primarily positive reinforcement and classical conditioning), and positive emotions, particularly ones which involve pleasure as a core component (e.g., joy, euphoria and ecstasy).

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Spinal cord

The spinal cord is a long, thin, tubular bundle of nervous tissue and support cells that extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column.

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Stimulation

Stimulation is the encouragement of development or the cause of activity generally.

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Synaptic plasticity

In neuroscience, synaptic plasticity is the ability of synapses to strengthen or weaken over time, in response to increases or decreases in their activity.

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Temporal lobe epilepsy

Temporal lobe epilepsy (TLE) is a chronic disorder of the nervous system characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.

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References

[1] https://en.wikipedia.org/wiki/Sensitization

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