Squalamine

Squalamine is a steroid-polyamine conjugate compound with broad spectrum antimicrobial activity and anti-angiogenic activity. ^[1]

9 relations: Calmodulin, Macular degeneration, Polyamine, Ranibizumab, Shark, Signal transduction, Spurdog, Steroid, Vascular endothelial growth factor.

Calmodulin

Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells.

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Macular degeneration

Macular degeneration, also known as age-related macular degeneration (AMD or ARMD), is a medical condition which may result in blurred or no vision in the center of the visual field.

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Polyamine

A polyamine is an organic compound having more than two amino groups.

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Ranibizumab

Ranibizumab (trade name Lucentis among others) is a monoclonal antibody fragment (Fab) created from the same parent mouse antibody as bevacizumab.

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Shark

Sharks are a group of elasmobranch fish characterized by a cartilaginous skeleton, five to seven gill slits on the sides of the head, and pectoral fins that are not fused to the head.

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Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.

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Spurdog

Squalus is a genus of dogfish sharks in the family Squalidae.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Vascular endothelial growth factor

Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels.

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Squalamine lactate.

References

[1] https://en.wikipedia.org/wiki/Squalamine

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