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Sunepitron

Index Sunepitron

Sunepitron (CP-93,393) is a combined 5-HT1A receptor agonist and α2-adrenergic receptor antagonist. [1]

15 relations: Agonist, Alpha-2 adrenergic receptor, Anxiety, Clinical trial, Hydrogenation, Lactam, Lesopitron, Major depressive disorder, Mandelic acid, Pfizer, Raney nickel, Receptor antagonist, Sodium azide, Succinic anhydride, 5-HT1A receptor.

Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Alpha-2 adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.

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Anxiety

Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behaviour such as pacing back and forth, somatic complaints, and rumination.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Hydrogenation

Hydrogenation – to treat with hydrogen – is a chemical reaction between molecular hydrogen (H2) and another compound or element, usually in the presence of a catalyst such as nickel, palladium or platinum.

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Lactam

A lactam is a cyclic amide.

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Lesopitron

Lesopitron (E-4424) is a selective full agonist of the 5-HT1A receptor which is structurally related to the azapirones.

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Major depressive disorder

Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.

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Mandelic acid

Mandelic acid is an aromatic alpha hydroxy acid with the molecular formula C6H5CH(OH)CO2H.

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Pfizer

Pfizer Inc. is an American pharmaceutical conglomerate headquartered in New York City, with its research headquarters in Groton, Connecticut.

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Raney nickel

Raney nickel, also called spongy nickel, is a fine-grained solid composed mostly of nickel derived from a nickel-aluminium alloy.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Sodium azide

Sodium azide is the inorganic compound with the formula NaN3.

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Succinic anhydride

Succinic anhydride, is an organic compound with the molecular formula (CH2CO)2O.

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5-HT1A receptor

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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References

[1] https://en.wikipedia.org/wiki/Sunepitron

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