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Merkel-cell carcinoma

Index Merkel-cell carcinoma

Merkel-cell carcinoma (MCC) is a rare and highly aggressive skin cancer, which, in most cases, is caused by the Merkel cell polyomavirus (MCV) discovered by scientists at the University of Pittsburgh in 2008. [1]

77 relations: Al Copeland, Al Davis, Antibody, Apudoma, Avelumab, Avigdor Arikha, Basal-cell carcinoma, Blood, Bone, Brain, Cancer immunotherapy, Carcinogenesis, Carl Epting Mundy Jr., Cell (biology), Chronic lymphocytic leukemia, Cyst, David Brudnoy, Ed Derwinski, Fascia, Finland, Geoffrey Parsons (pianist), H&E stain, Histology, HIV, HIV/AIDS, Illinois, Immune system, Immunosuppression, Incidence (epidemiology), Infection, Joe Zawinul, John Fitch (racing driver), Lindsay Thompson, Liver, Lung, Lymph node, Lymphoma, Malignancy, Maria Bueno, Max Perutz, Medical research, Melanoma, Merkel cell, Merkel cell polyomavirus, Metastasis, Micrograph, Monoclonal, Muscle, National Cancer Institute, National Football League, ..., National Institutes of Health, Neoplasm, Nodule (medicine), Oakland Raiders, Oncology, Organ transplantation, PD-L1, Polyomaviridae, Prognosis, Programmed cell death protein 1, Protein, Radiation therapy, Research, Skin cancer, Small-cell carcinoma, Squamous cell carcinoma, Subcutaneous tissue, Sunlight, Surgeon, The International League of Dermatological Societies, Ultraviolet, United States, United States House of Representatives, United States Secretary of Veterans Affairs, University of Pittsburgh, White people, William Morris Agency. Expand index (27 more) »

Al Copeland

Alvin Charles "Al" Copeland (February 2, 1944 – March 23, 2008) was an American entrepreneur who created the Popeyes Chicken & Biscuits fast food chain.

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Al Davis

Allen Davis (July 4, 1929 – October 8, 2011) was an American football coach and executive.

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Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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Apudoma

In pathology, an apudoma is an endocrine tumour that arises from an APUD cell from structures such as the ampulla of Vater.

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Avelumab

Avelumab (trade name Bavencio) is a fully human monoclonal antibody developed by Merck KGaA and Pfizer and Eli Lilly and Company in Canada as a pharmaceutical drug for use in immunotherapy, originally for the treatment of non-small-cell lung carcinoma (NSCLC).

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Avigdor Arikha

Avigdor Arikha (April 28, 1929 – April 29, 2010) was a Romanian-born French–Israeli painter, draughtsman, printmaker, and art historian.

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Basal-cell carcinoma

Basal-cell carcinoma (BCC), also known as basal-cell cancer, is the most common type of skin cancer.

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Blood

Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.

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Bone

A bone is a rigid organ that constitutes part of the vertebrate skeleton.

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Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

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Cancer immunotherapy

Cancer immunotherapy (sometimes called immuno-oncology, abbreviated IO) is the use of the immune system to treat cancer.

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Carcinogenesis

Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.

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Carl Epting Mundy Jr.

Carl Epting Mundy Jr. (July 16, 1935 – April 2, 2014) was a United States Marine Corps General who was the 30th Commandant of the United States Marine Corps and member of the Joint Chiefs of Staff from July 1, 1991 until his retirement on June 30, 1995, after over 41 years of service.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell).

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Cyst

A cyst is a closed sac, having a distinct membrane and division compared with the nearby tissue.

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David Brudnoy

David Barry Brudnoy (June 5, 1940 – December 9, 2004) was an American talk radio host in Boston from 1976 to 2004.

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Ed Derwinski

Edward Joseph Derwinski (September 15, 1926 – January 15, 2012) was an American politician who served as the first Cabinet-level United States Secretary of Veterans Affairs, serving under President George H. W. Bush from March 15, 1989 to September 26, 1992.

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Fascia

A fascia (plural fasciae; adjective fascial; from Latin: "band") is a band or sheet of connective tissue, primarily collagen, beneath the skin that attaches, stabilizes, encloses, and separates muscles and other internal organs.

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Finland

Finland (Suomi; Finland), officially the Republic of Finland is a country in Northern Europe bordering the Baltic Sea, Gulf of Bothnia, and Gulf of Finland, between Norway to the north, Sweden to the northwest, and Russia to the east.

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Geoffrey Parsons (pianist)

Geoffrey Penwill Parsons AO OBE (15 June 192926 January 1995) was an Australian pianist, most particularly notable as an accompanist to singers and instrumentalists.

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H&E stain

Hematoxylin and eosin stain or haematoxylin and eosin stain (H&E stain or HE stain) is one of the principal stains in histology.

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Histology

Histology, also microanatomy, is the study of the anatomy of cells and tissues of plants and animals using microscopy.

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HIV

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).

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HIV/AIDS

Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV).

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Illinois

Illinois is a state in the Midwestern region of the United States.

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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Immunosuppression

Immunosuppression is a reduction of the activation or efficacy of the immune system.

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Incidence (epidemiology)

Incidence in epidemiology is a measure of the probability of occurrence of a given medical condition in a population within a specified period of time.

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Infection

Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.

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Joe Zawinul

Josef Erich "Joe" Zawinul (7 July 1932 – 11 September 2007) was an Austrian jazz keyboardist and composer.

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John Fitch (racing driver)

John Cooper Fitch (August 4, 1917 in Indianapolis, Indiana – October 31, 2012) was an American racing driver and inventor.

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Lindsay Thompson

Lindsay Hamilton Simpson Thompson AO, CMG (15 October 1923 – 16 July 2008), Australian Liberal Party politician, was the 40th Premier of Victoria from June 1981 to April 1982 and was notable for his actions in the Faraday School kidnapping.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Lung

The lungs are the primary organs of the respiratory system in humans and many other animals including a few fish and some snails.

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Lymph node

A lymph node or lymph gland is an ovoid or kidney-shaped organ of the lymphatic system, and of the adaptive immune system, that is widely present throughout the body.

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Lymphoma

Lymphoma is a group of blood cancers that develop from lymphocytes (a type of white blood cell).

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Malignancy

Malignancy is the tendency of a medical condition to become progressively worse.

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Maria Bueno

Maria Esther Andion Bueno (11 October 1939 – 8 June 2018) was a Brazilian professional tennis player.

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Max Perutz

Max Ferdinand Perutz (19 May 1914 – 6 February 2002) was an Austrian-born British molecular biologist, who shared the 1962 Nobel Prize for Chemistry with John Kendrew, for their studies of the structures of haemoglobin and myoglobin.

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Medical research

Biomedical research (or experimental medicine) encompasses a wide array of research, extending from "basic research" (also called bench science or bench research), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials.

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Melanoma

Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.

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Merkel cell

Merkel cells, also known as Merkel-Ranvier cells or tactile epithelial cells, are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of vertebrates.

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Merkel cell polyomavirus

Merkel cell polyomavirus (MCV or MCPyV) was first described in January 2008 in Pittsburgh, Pennsylvania.

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Metastasis

Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.

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Micrograph

A micrograph or photomicrograph is a photograph or digital image taken through a microscope or similar device to show a magnified image of an item.

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Monoclonal

Monoclonal cells are a group of cells produced from a single ancestral cell by repeated cellular replication.

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Muscle

Muscle is a soft tissue found in most animals.

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National Cancer Institute

The National Cancer Institute (NCI) is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services.

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National Football League

The National Football League (NFL) is a professional American football league consisting of 32 teams, divided equally between the National Football Conference (NFC) and the American Football Conference (AFC).

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National Institutes of Health

The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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Nodule (medicine)

In medicine, nodules are solid, elevated areas of tissue or fluid inside or under the skin with a diameter greater than 0.5 centimeters.

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Oakland Raiders

The Oakland Raiders are a professional American football franchise based in Oakland, California.

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Oncology

Oncology is a branch of medicine that deals with the prevention, diagnosis, and treatment of cancer.

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Organ transplantation

Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ.

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PD-L1

Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.

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Polyomaviridae

Polyomaviridae is a family of viruses whose natural hosts are primarily mammals and birds.

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Prognosis

Prognosis (Greek: πρόγνωσις "fore-knowing, foreseeing") is a medical term for predicting the likely or expected development of a disease, including whether the signs and symptoms will improve or worsen (and how quickly) or remain stable over time; expectations of quality of life, such as the ability to carry out daily activities; the potential for complications and associated health issues; and the likelihood of survival (including life expectancy).

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Programmed cell death protein 1

Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Radiation therapy

Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is therapy using ionizing radiation, generally as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator.

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Research

Research comprises "creative and systematic work undertaken to increase the stock of knowledge, including knowledge of humans, culture and society, and the use of this stock of knowledge to devise new applications." It is used to establish or confirm facts, reaffirm the results of previous work, solve new or existing problems, support theorems, or develop new theories.

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Skin cancer

Skin cancers are cancers that arise from the skin.

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Small-cell carcinoma

Small-cell carcinoma (also known as "small-cell lung cancer", or "oat-cell carcinoma") is a type of highly malignant cancer that most commonly arises within the lung, although it can occasionally arise in other body sites, such as the cervix, prostate, and gastrointestinal tract.

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Squamous cell carcinoma

Squamous cell carcinomas, also known as epidermoid carcinoma are a number of different types of cancer that result from squamous cells.

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Subcutaneous tissue

The subcutaneous tissue, also called the hypodermis, hypoderm, subcutis, or superficial fascia, is the lowermost layer of the integumentary system in vertebrates.

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Sunlight

Sunlight is a portion of the electromagnetic radiation given off by the Sun, in particular infrared, visible, and ultraviolet light.

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Surgeon

In medicine, a surgeon is a physician who performs surgical operations.

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The International League of Dermatological Societies

The International League of Dermatological Societies (ILDS) is a non-governmental organization that works closely with the World Health Organization.

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Ultraviolet

Ultraviolet (UV) is electromagnetic radiation with a wavelength from 10 nm to 400 nm, shorter than that of visible light but longer than X-rays.

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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United States House of Representatives

The United States House of Representatives is the lower chamber of the United States Congress, the Senate being the upper chamber.

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United States Secretary of Veterans Affairs

The United States Secretary of Veterans Affairs is the head of the United States Department of Veterans Affairs, the department concerned with veterans' benefits, health care, and national veterans' memorials and cemeteries.

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University of Pittsburgh

The University of Pittsburgh (commonly referred to as Pitt) is a state-related research university located in Pittsburgh, Pennsylvania.

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White people

White people is a racial classification specifier, used mostly for people of European descent; depending on context, nationality, and point of view, the term has at times been expanded to encompass certain persons of North African, Middle Eastern, and South Asian descent, persons who are often considered non-white in other contexts.

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William Morris Agency

The William Morris Agency (also known as WMA) was a Hollywood-based talent agency.

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Redirects here:

Carcinoma, merkel cell, Cutaneous apudoma, Merkel Cell Carcinoma, Merkel Cell carcinoma, Merkel cell cancer, Merkel cell carcinoma, Primary neuroendocrine carcinoma of the skin, Primary small cell carcinoma of the skin, Trabecular cancer, Trabecular cancer of the skin, Trabecular carcinoma, Trabecular carcinoma of the skin.

References

[1] https://en.wikipedia.org/wiki/Merkel-cell_carcinoma

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