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Ultra-conserved element

Index Ultra-conserved element

An ultra-conserved element (UCE) is a region of DNA that is identical in at least two different species. [1]

22 relations: Carcinoma, Conserved sequence, DNA, Enhancer (genetics), Evolution, Hepatocellular carcinoma, Hippocampus, Human accelerated regions, Human genome, Knockout, Leukemia, Negative selection (natural selection), Neutral theory of molecular evolution, Non-coding DNA, Non-coding RNA, Nucleic acid sequence, Nucleotide, RNA splicing, Synteny, Takifugu rubripes, TUC338, UCbase.

Carcinoma

Carcinoma is a type of cancer that develops from epithelial cells.

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Conserved sequence

In evolutionary biology, conserved sequences are similar or identical sequences in nucleic acids (DNA and RNA) or proteins across species (orthologous sequences) or within a genome (paralogous sequences).

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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Enhancer (genetics)

In genetics, an enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins (activators) to increase the likelihood that transcription of a particular gene will occur.

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Evolution

Evolution is change in the heritable characteristics of biological populations over successive generations.

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Hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and is the most common cause of death in people with cirrhosis.

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Hippocampus

The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.

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Human accelerated regions

Human accelerated regions (HARs), first described in August 2006, are a set of 49 segments of the human genome that are conserved throughout vertebrate evolution but are strikingly different in humans.

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Human genome

The human genome is the complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria.

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Knockout

A knockout (abbreviated to KO or K.O.) is a fight-ending, winning criterion in several full-contact combat sports, such as boxing, kickboxing, muay thai, mixed martial arts, karate, some forms of taekwondo, and other sports involving striking, as well as fighting-based video games.

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Leukemia

Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.

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Negative selection (natural selection)

In natural selection, negative selection or purifying selection is the selective removal of alleles that are deleterious.

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Neutral theory of molecular evolution

The neutral theory of molecular evolution holds that at the molecular level most evolutionary changes and most of the variation within and between species is not caused by natural selection but by genetic drift of mutant alleles that are neutral.

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Non-coding DNA

In genomics and related disciplines, noncoding DNA sequences are components of an organism's DNA that do not encode protein sequences.

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Non-coding RNA

A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein.

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Nucleic acid sequence

A nucleic acid sequence is a succession of letters that indicate the order of nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule.

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Nucleotide

Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.

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RNA splicing

In molecular biology, splicing is the editing of the nascent precursor messenger RNA (pre-mRNA) transcript into a mature messenger RNA (mRNA).

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Synteny

In classical genetics, synteny describes the physical co-localization of genetic loci on the same chromosome within an individual or species.

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Takifugu rubripes

Takifugu rubripes, commonly known as the Japanese puffer, Tiger puffer, or torafugu (虎河豚), is a pufferfish in the genus Takifugu. It is distinguished by a very small genome that has been fully sequenced because of its use as a model species and is in widespread use as a reference in genomics.

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TUC338

TUC338 (transcribed ultra-conserved region 338) is an ultra-conserved element which is transcribed to give a non-coding RNA.

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UCbase

UCbase is a database of ultraconserved sequences (UCRs or UCEs) that were first described by Bejerano, G. et al.

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Redirects here:

UcRNA, Ultra-conserved region, Ultraconserved area, Ultraconserved element.

References

[1] https://en.wikipedia.org/wiki/Ultra-conserved_element

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