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51 relations: Acute myeloid leukemia, Adenocarcinoma, Alternative splicing, C-terminus, Cancer immunotherapy, Cell growth, Clinical trial, Cytidine, Cytoplasm, Denys–Drash syndrome, DNA-binding domain, EGR1, EGR2, Epithelium, Fallopian tube, Gene, Genitourinary system, Glutamine, HtrA serine peptidase 2, IDH1, IDH2, Immunohistochemistry, Innate immune system, Kidney disease, Malignancy, Mammal, Mesothelioma, Mesothelium, Messenger RNA, Mutual exclusivity, N-terminus, National Cancer Institute, Neoplasm, P53, PAWR, Product (chemistry), Proline, Protein, Protein–protein interaction, RNA editing, Steroidogenic factor 1, Tet methylcytosine dioxygenase 2, Transcription factor, Tumor suppressor, U2AF2, UBE2I, Uridine, Vaccine, Wilms' tumor, WTAP (gene), ..., Zinc finger. Expand index (1 more) »
Acute myeloid leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells.
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Adenocarcinoma
Adenocarcinoma (plural adenocarcinomas or adenocarcinomata) is a type of cancerous tumor that can occur in several parts of the body.
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Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
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C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
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Cancer immunotherapy
Cancer immunotherapy (sometimes called immuno-oncology, abbreviated IO) is the use of the immune system to treat cancer.
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Cell growth
The term cell growth is used in the contexts of biological cell development and cell division (reproduction).
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Clinical trial
Clinical trials are experiments or observations done in clinical research.
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Cytidine
Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a β-N1-glycosidic bond.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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Denys–Drash syndrome
Denys–Drash syndrome (DDS) or Drash syndrome is a rare disorder or syndrome characterized by gonadal dysgenesis, nephropathy, and Wilms' tumor.
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DNA-binding domain
A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded DNA.
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EGR1
EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene.
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EGR2
Early growth response protein 2 is a protein that in humans is encoded by the EGR2 gene.
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Epithelium
Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.
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Fallopian tube
The Fallopian tubes, also known as uterine tubes or salpinges (singular salpinx), are two very fine tubes lined with ciliated epithelia, leading from the ovaries of female mammals into the uterus, via the uterotubal junction.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Genitourinary system
The genitourinary system or urogenital system is the organ system of the reproductive organs and the urinary system.
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Glutamine
Glutamine (symbol Gln or Q) is an α-amino acid that is used in the biosynthesis of proteins.
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HtrA serine peptidase 2
Serine protease HTRA2, mitochondrial is an enzyme that in humans is encoded by the HTRA2 gene.
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IDH1
Isocitrate dehydrogenase 1 (NADP+), soluble is an enzyme that in humans is encoded by the IDH1 gene on chromosome 2.
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IDH2
Isocitrate dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the IDH2 gene.
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Immunohistochemistry
Immunohistochemistry (IHC) involves the process of selectively imaging antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues.
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Innate immune system
The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms.
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Kidney disease
Kidney disease, or renal disease, also known as nephropathy, is damage to or disease of a kidney.
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Malignancy
Malignancy is the tendency of a medical condition to become progressively worse.
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Mammal
Mammals are the vertebrates within the class Mammalia (from Latin mamma "breast"), a clade of endothermic amniotes distinguished from reptiles (including birds) by the possession of a neocortex (a region of the brain), hair, three middle ear bones, and mammary glands.
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Mesothelioma
Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs (known as the mesothelium).
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Mesothelium
The mesothelium is a membrane composed of simple squamous epithelium that forms the lining of several body cavities: the pleura (thoracic cavity), peritoneum (abdominal cavity including the mesentery), mediastinum and pericardium (heart sac).
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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Mutual exclusivity
In logic and probability theory, two events (or propositions) are mutually exclusive or disjoint if they cannot both occur (be true).
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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National Cancer Institute
The National Cancer Institute (NCI) is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services.
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Neoplasm
Neoplasia is a type of abnormal and excessive growth of tissue.
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P53
Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).
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PAWR
PRKC, apoptosis, WT1, regulator, also known as PAWR or Prostate apoptosis response-4 (Par-4), is a human gene coding for a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal cells.
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Product (chemistry)
Products are the species formed from chemical reactions.
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Proline
Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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RNA editing
RNA editing is a molecular process through which some cells can make discrete changes to specific nucleotide sequences within an RNA molecule after it has been generated by RNA polymerase.
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Steroidogenic factor 1
The steroidogenic factor 1 (SF-1) protein is a transcription factor involved in sex determination by controlling activity of genes related to the reproductive glands or gonads and adrenal glands.
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Tet methylcytosine dioxygenase 2
Tet methylcytosine dioxygenase 2 (TET2) is a human gene.
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Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
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Tumor suppressor
A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer.
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U2AF2
Splicing factor U2AF 65 kDa subunit is a protein that in humans is encoded by the U2AF2 gene.
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UBE2I
SUMO-conjugating enzyme UBC9 is an enzyme that in humans is encoded by the UBE2I gene.
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Uridine
Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, a ribofuranose) via a β-N1-glycosidic bond.
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Vaccine
A vaccine is a biological preparation that provides active acquired immunity to a particular disease.
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Wilms' tumor
Wilms tumor, also known as nephroblastoma, is a cancer of the kidneys that typically occurs in children, rarely in adults.
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WTAP (gene)
Pre-mRNA-splicing regulator WTAP is a protein that in humans is encoded by the WTAP gene.
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Zinc finger
A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) in order to stabilize the fold.
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Redirects here:
WIT-2, WT1 (gene), WT33, Wilms tumor 1, Wit-2, Wt33.
References
[1] https://en.wikipedia.org/wiki/WT1
