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Y chromosome microdeletion

Y chromosome microdeletion (YCM) is a family of genetic disorders caused by missing gene(s) in the Y chromosome. [1]

21 relations: Azoospermia, Azoospermia factor, Base pair, DAZ1, DNA sequencing, Fertility, Gel electrophoresis, Genetic disorder, Genetic marker, Infertility, Male infertility, Mutation, Natural selection, Oligospermia, Polymerase chain reaction, Semen analysis, Sequence-tagged site, Spermatogenesis, TSPY1, White blood cell, Y chromosome.

Azoospermia

Azoospermia is the medical condition of a man not having any measurable level of sperm in his semen.

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Azoospermia factor

Azoospermia factor (AZF) refers to one of several proteins or their genes, which are coded from the AZF region on the human male Y chromosome.

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Base pair

Base pairs (unit: bp), which form between specific nucleobases (also termed nitrogenous bases), are the building blocks of the DNA double helix and contribute to the folded structure of both DNA and RNA.

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DAZ1

Deleted in azoospermia 1, also known as DAZ1, is a protein which in humans is encoded by the DAZ1 gene.

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DNA sequencing

DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule.

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Fertility

Fertility is the natural capability to produce offspring.

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Gel electrophoresis

Gel electrophoresis is a method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge.

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Genetic disorder

A genetic disorder is a genetic problem caused by one or more abnormalities in the genome, especially a condition that is present from birth (congenital).

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Genetic marker

A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species.

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Infertility

Infertility is the inability of a person, animal or plant to reproduce by natural means.

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Male infertility

Male infertility refers to a male's inability to cause pregnancy in a fertile female.

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Mutation

In biology, a mutation is a permanent change of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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Natural selection

Natural selection is the differential survival and reproduction of individuals due to differences in phenotype; it is a key mechanism of evolution.

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Oligospermia

Oligozoospermia, refers to semen with a low concentration of sperm and is a common finding in male infertility.

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Polymerase chain reaction

The polymerase chain reaction (PCR) is a technology in molecular biology used to amplify a single copy or a few copies of a piece of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.

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Semen analysis

A semen analysis (plural: semen analyses) evaluates certain characteristics of a male's semen and the sperm contained therein.

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Sequence-tagged site

A sequence-tagged site (or STS) is a short (200 to 500 base pair) DNA sequence that has a single occurrence in the genome and whose location and base sequence are known.

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Spermatogenesis

Spermatogenesis is the process in which spermatozoa are produced from male primordial germ cells by way of mitosis and meiosis.

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TSPY1

Testis-specific Y-encoded protein 1 is a protein that in humans is encoded by the TSPY1 gene.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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Y chromosome

The Y chromosome is one of two sex chromosomes (allosomes) in mammals, including humans, and many other animals.

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Redirects here:

Y Chromosome Microdeletion, Y chromosome deletion, Y chromosome deletions, YCM.

References

[1] https://en.wikipedia.org/wiki/Y_chromosome_microdeletion

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