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Aminopterin and Monoclonal antibody

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between Aminopterin and Monoclonal antibody

Aminopterin vs. Monoclonal antibody

Aminopterin (or 4-aminopteroic acid), the 4-amino derivative of folic acid, is an antineoplastic drug with immunosuppressive properties often used in chemotherapy. Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.

Similarities between Aminopterin and Monoclonal antibody

Aminopterin and Monoclonal antibody have 7 things in common (in Unionpedia): Cell culture, Dihydrofolate reductase, Folate, Food and Drug Administration, HAT medium, Hybridoma technology, Leukemia.

Cell culture

Cell culture is the process by which cells are grown under controlled conditions, generally outside their natural environment.

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Dihydrofolate reductase

Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.

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Folate

Folate, distinct forms of which are known as folic acid, folacin, and vitamin B9, is one of the B vitamins.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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HAT medium

HAT Medium (hypoxanthine-aminopterin-thymidine medium) is a selection medium for mammalian cell culture, which relies on the combination of aminopterin, a drug that acts as a powerful folate metabolism inhibitor by inhibiting dihydrofolate reductase, with hypoxanthine (a purine derivative) and thymidine (a deoxynucleoside) which are intermediates in DNA synthesis.

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Hybridoma technology

Hybridoma technology is a method for producing large numbers of identical antibodies (also called monoclonal antibodies).

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Leukemia

Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.

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The list above answers the following questions

Aminopterin and Monoclonal antibody Comparison

Aminopterin has 69 relations, while Monoclonal antibody has 177. As they have in common 7, the Jaccard index is 2.85% = 7 / (69 + 177).

References

This article shows the relationship between Aminopterin and Monoclonal antibody. To access each article from which the information was extracted, please visit:

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