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170 relations: ABC News, Adverse drug reaction, Alcoholic drink, Alice in Chains, Alprazolam, Alternative medicine, American Broadcasting Company, Amphetamine, Anabolic steroid, Anissa Jones, Anna Nicole Smith, Antidepressant, Associated Press, Automation, Avenged Sevenfold, Barbiturate, Benzodiazepine, Board certification, Brain damage, Brain death, Brent Mydland, Bridgette Andersen, Buprenorphine, California Pacific Medical Center, California v. Murray, Cannabis (drug), Carisoprodol, Chloral hydrate, Chris Farley, Chris Penn, Ciprofloxacin, Citalopram, Clonazepam, CNN, Cocaine, Codeine, Cory Monteith, Cyclobenzaprine, Dana Plato, Daniel Wayne Smith, Deep Purple, Def Leppard, Derek Boogaard, Dextropropoxyphene, Diazepam, Diphenhydramine, Doxylamine, Drug interaction, Edie Sedgwick, Eight Is Enough, ..., Elisa Bridges, Elvis Presley, EMF (band), Eric Douglas, Escitalopram, Fentanyl, Fluoxetine, Freddy Soto, Gannett Company, George C. Nichopoulos, Geraldo Rivera, Gin and tonic, Grateful Dead, Hawthorne Heights, Heath Ledger, Heroin, Hydrocodone, Hydrocodone/paracetamol, Hypochondriasis, Janis Joplin, Jerry Garcia Band, Jimi Hendrix, John Belushi, John Kahn, Johnny O'Keefe, Ken Caminiti, Kennedy family, Kris Kross, Lani O'Grady, Layne Staley, Lester Bangs, License, List of deaths from drug overdose and intoxication, LiveDaily, Lorazepam, Louie Spicolli, Medical prescription, Medical ventilator, Medscape, Methadone, Methamphetamine, Methaqualone, Methocarbamol, Methylenedioxyamphetamine, Michael Jackson, Miss Elizabeth, Mitch Hedberg, Morphine, MSNBC, MTV, New York Rangers, Nick Adams (actor, born 1931), Nordazepam, Ol' Dirty Bastard, Opioid, Oseltamivir, Osteopathic medicine, Over-the-counter drug, Oxazepam, Oxycodone, Oxycodone/paracetamol, Oxygen, Oxymorphone, Paracetamol, Paraldehyde, Paul Gray (American musician), Persistent vegetative state, Pethidine, Pharmacology, Pharmacovigilance, Phencyclidine, Philip Seymour Hoffman, Physician, Pneumonia, Poly drug use, Polypharmacy, Prescription drug, Promazine, Propofol, Recreational drug use, Respiratory failure, Right to die, River Phoenix, Robert F. Kennedy, Rodney King, Scott Weiland, Secobarbital, Sedative, Sertraline, Slipknot (band), SoHo, Manhattan, Speedball (drug), Steve Clark, Stone Temple Pilots, Substance abuse, Substituted amphetamine, Supreme Court of New Jersey, Temazepam, The Age, The New York Times, The Rev, Theraflu, Thioridazine, Ticketmaster, Tommy Bolin, Topiramate, Toxicity, Toxicology, Tramadol, Trevor Goddard, Truman Capote, University of California, San Diego, Unnatural death, USA Today, Velvet Revolver, Vicks, Whitney Houston, World Wide Web, Wu-Tang Clan, 20/20 (U.S. TV series). Expand index (120 more) »
ABC News
ABC News is the news division of the American Broadcasting Company (ABC), owned by the Disney Media Networks division of The Walt Disney Company.
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Adverse drug reaction
An adverse drug reaction (ADR) is an injury caused by taking a medication.
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Alcoholic drink
An alcoholic drink (or alcoholic beverage) is a drink that contains ethanol, a type of alcohol produced by fermentation of grains, fruits, or other sources of sugar.
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Alice in Chains
Alice in Chains is an American rock band from Seattle, Washington, formed in 1987 by guitarist/vocalist Jerry Cantrell and drummer Sean Kinney, who then recruited bassist Mike Starr and lead vocalist Layne Staley.
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Alprazolam
Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer.
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Alternative medicine
Alternative medicine, fringe medicine, pseudomedicine or simply questionable medicine is the use and promotion of practices which are unproven, disproven, impossible to prove, or excessively harmful in relation to their effect — in the attempt to achieve the healing effects of medicine.--> --> --> They differ from experimental medicine in that the latter employs responsible investigation, and accepts results that show it to be ineffective. The scientific consensus is that alternative therapies either do not, or cannot, work. In some cases laws of nature are violated by their basic claims; in some the treatment is so much worse that its use is unethical. Alternative practices, products, and therapies range from only ineffective to having known harmful and toxic effects.--> Alternative therapies may be credited for perceived improvement through placebo effects, decreased use or effect of medical treatment (and therefore either decreased side effects; or nocebo effects towards standard treatment),--> or the natural course of the condition or disease. Alternative treatment is not the same as experimental treatment or traditional medicine, although both can be misused in ways that are alternative. Alternative or complementary medicine is dangerous because it may discourage people from getting the best possible treatment, and may lead to a false understanding of the body and of science.-->---> Alternative medicine is used by a significant number of people, though its popularity is often overstated.--> Large amounts of funding go to testing alternative medicine, with more than US$2.5 billion spent by the United States government alone.--> Almost none show any effect beyond that of false treatment,--> and most studies showing any effect have been statistical flukes. Alternative medicine is a highly profitable industry, with a strong lobby. This fact is often overlooked by media or intentionally kept hidden, with alternative practice being portrayed positively when compared to "big pharma". --> The lobby has successfully pushed for alternative therapies to be subject to far less regulation than conventional medicine.--> Alternative therapies may even be allowed to promote use when there is demonstrably no effect, only a tradition of use. Regulation and licensing of alternative medicine and health care providers varies between and within countries. Despite laws making it illegal to market or promote alternative therapies for use in cancer treatment, many practitioners promote them.--> Alternative medicine is criticized for taking advantage of the weakest members of society.--! Terminology has shifted over time, reflecting the preferred branding of practitioners.. Science Based Medicine--> For example, the United States National Institutes of Health department studying alternative medicine, currently named National Center for Complementary and Integrative Health, was established as the Office of Alternative Medicine and was renamed the National Center for Complementary and Alternative Medicine before obtaining its current name. Therapies are often framed as "natural" or "holistic", in apparent opposition to conventional medicine which is "artificial" and "narrow in scope", statements which are intentionally misleading. --> When used together with functional medical treatment, alternative therapies do not "complement" (improve the effect of, or mitigate the side effects of) treatment.--> Significant drug interactions caused by alternative therapies may instead negatively impact functional treatment, making it less effective, notably in cancer.--> Alternative diagnoses and treatments are not part of medicine, or of science-based curricula in medical schools, nor are they used in any practice based on scientific knowledge or experience.--> Alternative therapies are often based on religious belief, tradition, superstition, belief in supernatural energies, pseudoscience, errors in reasoning, propaganda, fraud, or lies.--> Alternative medicine is based on misleading statements, quackery, pseudoscience, antiscience, fraud, and poor scientific methodology. Promoting alternative medicine has been called dangerous and unethical.--> Testing alternative medicine that has no scientific basis has been called a waste of scarce research resources.--> Critics state that "there is really no such thing as alternative medicine, just medicine that works and medicine that doesn't",--> that the very idea of "alternative" treatments is paradoxical, as any treatment proven to work is by definition "medicine".-->.
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American Broadcasting Company
The American Broadcasting Company (ABC) is an American commercial broadcast television network that is a flagship property of Disney–ABC Television Group, a subsidiary of the Disney Media Networks division of The Walt Disney Company.
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Amphetamine
Amphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.
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Anabolic steroid
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.
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Anissa Jones
Mary Anissa Jones (March 11, 1958 – August 28, 1976) was an American child actress known for her role as Buffy on the CBS sitcom Family Affair, which ran from 1966 to 1971.
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Anna Nicole Smith
Anna Nicole Smith (born Vickie Lynn Hogan; November 28, 1967 – February 8, 2007) was an American model, actress and television personality.
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Antidepressant
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
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Associated Press
The Associated Press (AP) is a U.S.-based not-for-profit news agency headquartered in New York City.
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Automation
Automation is the technology by which a process or procedure is performed without human assistance.
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Avenged Sevenfold
Avenged Sevenfold (sometimes abbreviated as A7X) is an American heavy metal band from Huntington Beach, California, formed in 1999.
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Barbiturate
A barbiturate is a drug that acts as a central nervous system depressant, and can therefore produce a wide spectrum of effects, from mild sedation to death.
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Benzodiazepine
Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.
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Board certification
Board certification is the process by which a physician or other professional demonstrates a mastery of basic knowledge and skills through written, practical, or simulator-based testing.
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Brain damage
Brain damage or brain injury (BI) is the destruction or degeneration of brain cells.
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Brain death
Brain death is the complete loss of brain function (including involuntary activity necessary to sustain life).
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Brent Mydland
Brent Mydland (October 21, 1952 – July 26, 1990) was an American keyboardist, vocalist and songwriter.
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Bridgette Andersen
Marriah Bridget Andersen (July 11, 1975 – May 18, 1997), professionally known as Bridgette Andersen, was an American television and film actress who began her career as a child model at the age of 2.
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Buprenorphine
Buprenorphine, sold under the brand name Subutex, among others, is an opioid used to treat opioid addiction, acute pain, and chronic pain.
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California Pacific Medical Center
California Pacific Medical Center (CPMC) is the largest medical center of the Northern California-based Sutter Health health system and is the result of the merger of several of the longest established hospitals in San Francisco.
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California v. Murray
The trial of Conrad Murray (People of the State of California v. Conrad Robert Murray) was the American criminal trial of Michael Jackson's personal physician, Conrad Murray, who was charged with involuntary manslaughter for the pop singer's death on June 25, 2009, from a massive overdose of the general anesthetic propofol.
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Cannabis (drug)
Cannabis, also known as marijuana among other names, is a psychoactive drug from the ''Cannabis'' plant intended for medical or recreational use.
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Carisoprodol
Carisoprodol, marketed under the brand name Soma among others, is a prescription drug marketed since 1959.
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Chloral hydrate
Chloral hydrate is a geminal diol with the formula C2H3Cl3O2.
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Chris Farley
Christopher Crosby Farley (February 15, 1964 – December 18, 1997) was an American actor and comedian.
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Chris Penn
Christopher Shannon Penn (October 10, 1965 – January 24, 2006) was an American film and television actor.
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Ciprofloxacin
Ciprofloxacin is an antibiotic used to treat a number of bacterial infections.
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Citalopram
Citalopram (brand names: Celexa, Cipramil and others) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class.
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Clonazepam
Clonazepam, sold under the brand name Klonopin among others, is a medication used to prevent and treat seizures, panic disorder, and for the movement disorder known as akathisia.
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CNN
Cable News Network (CNN) is an American basic cable and satellite television news channel and an independent subsidiary of AT&T's WarnerMedia.
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Cocaine
Cocaine, also known as coke, is a strong stimulant mostly used as a recreational drug.
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Codeine
Codeine is an opiate used to treat pain, as a cough medicine, and for diarrhea. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen. Evidence does not support its use for acute cough suppression in children or adults. In Europe it is not recommended as a cough medicine in those under twelve years of age. It is generally taken by mouth. It typically starts working after half an hour with maximum effect at two hours. The total duration of its effects last for about four to six hours. Common side effects include vomiting, constipation, itchiness, lightheadedness, and drowsiness. Serious side effects may include breathing difficulties and addiction. It is unclear if its use in pregnancy is safe. Care should be used during breastfeeding as it may result in opiate toxicity in the baby. Its use as of 2016 is not recommended in children. Codeine works following being broken down by the liver into morphine. How quickly this occurs depends on a person's genetics. Codeine was discovered in 1832 by Pierre Jean Robiquet. In 2013 about 361,000 kilograms of codeine were produced while 249,000 kilograms were used. This makes it the most commonly taken opiate. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is between 0.04 and 0.29 USD per dose as of 2014. In the United States it costs about one dollar a dose. Codeine occurs naturally and makes up about 2% of opium.
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Cory Monteith
Cory Allan Michael Monteith (May 11, 1982 July 13, 2013) was a Canadian actor and musician, known for his role as Finn Hudson on the Fox television series Glee.
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Cyclobenzaprine
Cyclobenzaprine, sold under the brand name Flexeril among others, is a muscle relaxer medication used to relieve skeletal muscle spasms and associated pain in acute musculoskeletal conditions.
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Dana Plato
Dana Michelle Plato (born Dana Michelle Strain; November 7, 1964 – May 8, 1999) was an American actress who was notable for having played the role of Kimberly Drummond on the U.S. television sitcom Diff'rent Strokes, from 1978 to 1986.
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Daniel Wayne Smith
Daniel Wayne Smith (January 22, 1986 – September 10, 2006) was the son of the American model and actress Anna Nicole and Billy Wayne Smith.
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Deep Purple
Deep Purple are an English rock band formed in Hertford in 1968.
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Def Leppard
Def Leppard are an English rock band formed in 1977 in Sheffield as part of the new wave of British heavy metal movement.
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Derek Boogaard
Derek Leendert Boogaard (later; June 23, 1982 – May 13, 2011) was a Canadian professional ice hockey left winger who played for the Minnesota Wild and the New York Rangers of the National Hockey League (NHL).
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Dextropropoxyphene
Dextropropoxyphene is an analgesic in the opioid category, patented in 1955 and manufactured by Eli Lilly and Company.
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Diazepam
Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that typically produces a calming effect.
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Diphenhydramine
Diphenhydramine is an antihistamine mainly used to treat allergies.
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Doxylamine
Doxylamine is a first-generation antihistamine.
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Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together.
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Edie Sedgwick
Edith Minturn Sedgwick (April 20, 1943 – November 16, 1971) was an American actress and fashion model.
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Eight Is Enough
Eight Is Enough is an American television comedy-drama series that ran on ABC from March 15, 1977 until May 23, 1981.
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Elisa Bridges
Elisa Rebeca Bridges (May 24, 1973 – February 7, 2002) was an American actress and model.
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Elvis Presley
Elvis Aaron Presley (January 8, 1935 – August 16, 1977) was an American singer and actor.
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EMF (band)
EMF are a British alternative rock band from Cinderford, Gloucestershire, who came to prominence at the beginning of the 1990s.
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Eric Douglas
Eric Anthony Douglas (June 21, 1958 – July 6, 2004) was an American actor and stand-up comedian.
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Escitalopram
Escitalopram, sold under the brand names Cipralex and Lexapro among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
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Fentanyl
Fentanyl, also spelled fentanil, is an opioid which is used as a pain medication and together with other medications for anesthesia. Fentanyl is also made illegally and used as a recreational drug, often mixed with heroin or cocaine. It has a rapid onset and effects generally last less than an hour or two. Medically, fentanyl is used by injection, as a patch on the skin, as a nasal spray, or in the mouth. Common side effects include vomiting, constipation, sedation, confusion, hallucinations, and injuries related to poor coordination. Serious side effects may include decreased breathing (respiratory depression), serotonin syndrome, low blood pressure, addiction, or coma. In 2016, more than 20,000 deaths occurred in the United States due to overdoses of fentanyl and fentanyl analogues, half of all reported opioid related deaths. Fentanyl works primarily by activating μ-opioid receptors. It is around 100 times stronger than morphine, and some analogues such as carfentanil are around 10,000 times stronger. Fentanyl was first made by Paul Janssen in 1960 and approved for medical use in the United States in 1968.In 2015, were used in healthcare globally., fentanyl was the most widely used synthetic opioid in medicine. Fentanyl patches are on the WHO List of Essential Medicines, the most effective and safe medicines needed in a health system. For a 100 microgram vial, the average wholesale cost in the developing world is 0.66 (2015). and in the USA it costs 0.49 (2017).
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Fluoxetine
Fluoxetine, also known by trade names Prozac and Sarafem, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
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Freddy Soto
Alfredo "Freddy" Soto, Jr. (June 22, 1970 – July 10, 2005) was an American comedian, writer and actor.
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Gannett Company
Gannett Company, Inc. is a publicly traded American media holding company headquartered in Tysons Corner, Virginia, near McLean in Greater Washington DC.
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George C. Nichopoulos
George Constantine Nichopoulos (October 29, 1927 – February 24, 2016), also known as Dr.
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Geraldo Rivera
Geraldo Rivera (born Gerald Michael Rivera; July 4, 1943) is an American attorney, reporter, author, and talk show host.
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Gin and tonic
A gin and tonic is a highball cocktail made with gin and tonic water poured over ice.
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Grateful Dead
The Grateful Dead was an American rock band formed in 1965 in Palo Alto, California.
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Hawthorne Heights
Hawthorne Heights is an American rock band from Dayton, Ohio, formed in 2001.
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Heath Ledger
Heath Andrew Ledger (4 April 197922 January 2008) was an Australian actor and director.
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Heroin
Heroin, also known as diamorphine among other names, is an opioid most commonly used as a recreational drug for its euphoric effects.
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Hydrocodone
Hydrocodone, sold under brand names such as Vicodin and Norco among many others, is a semisynthetic opioid derived from codeine, one of the opioid alkaloids found in the opium poppy.
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Hydrocodone/paracetamol
Hydrocodone/paracetamol, also known as hydrocodone/acetaminophen or hydrocodone/APAP and marketed under the trade name Vicodin and Norco among others, is the combination of an opioid pain medication, hydrocodone, with paracetamol (acetaminophen).
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Hypochondriasis
Hypochondriasis or hypochondria is a condition in which a person is excessively and unduly worried about having a serious illness.
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Janis Joplin
Janis Lyn Joplin (January 19, 1943 – October 4, 1970) nicknamed The Pearl, was an American rock, soul and blues singer and songwriter, and one of the most successful and widely-known female rock stars of her era.
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Jerry Garcia Band
The Jerry Garcia Band was a San Francisco Bay Area rock band led by Jerry Garcia of the Grateful Dead.
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Jimi Hendrix
James Marshall "Jimi" Hendrix (born Johnny Allen Hendrix; November 27, 1942 – September 18, 1970) was an American rock guitarist, singer, and songwriter.
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John Belushi
John Adam Belushi (January 24, 1949 – March 5, 1982) was an American comedian, actor, and singer.
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John Kahn
John Kahn (June 13, 1947 – May 30, 1996) was an American electric and acoustic bassist.
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Johnny O'Keefe
John Michael O'Keefe (19 January 1935 – 6 October 1978) was an Australian rock and roll singer whose career began in the 1950s.
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Ken Caminiti
Kenneth Gene Caminiti (April 21, 1963 – October 10, 2004) was an American third baseman who spent fifteen seasons in Major League Baseball (MLB) with the Houston Astros (1987–1994, 1999–2000), San Diego Padres (1995–1998), Texas Rangers (2001) and Atlanta Braves (2001).
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Kennedy family
The Kennedy family is an American political family that has long been prominent in American politics, public service, and business.
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Kris Kross
Kris Kross was an American hip hop duo formed in the early 1990s that consisted of Chris "Mac Daddy" Kelly and Chris "Daddy Mac" Smith.
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Lani O'Grady
Lani O'Grady (October 2, 1954 – September 25, 2001) was an American actress and talent agent.
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Layne Staley
Layne Staley (born Layne Rutherford Staley, August 22, 1967 – April 5, 2002) was an American musician known for being the lead vocalist, occasional rhythm guitarist and co-songwriter of the rock band Alice in Chains from 1987 until 1998.
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Lester Bangs
Leslie Conway "Lester" Bangs (December 14, 1948 – April 30, 1982) was an American music journalist, critic, author, and musician.
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License
A license (American English) or licence (British English) is an official permission or permit to do, use, or own something (as well as the document of that permission or permit).
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List of deaths from drug overdose and intoxication
Drug overdose and intoxication are significant causes of accidental death, and can also be used as a form of suicide.
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LiveDaily
LiveDaily was a music and entertainment site owned by Ticketmaster, created in 1998 and seen in the United States, Canada, and United Kingdom.
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Lorazepam
Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication.
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Louie Spicolli
Louis Mucciolo Jr. (February 10, 1971 – February 15, 1998) was an American professional wrestler.
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Medical prescription
A prescription is a health-care program implemented by a physician or other qualified health care practitioner in the form of instructions that govern the plan of care for an individual patient.
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Medical ventilator
A medical ventilator (or simply ventilator in context) is a mechanical ventilator, a machine designed to move breathable air into and out of the lungs, to provide breathing for a patient who is physically unable to breathe, or breathing insufficiently.
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Medscape
Medscape is a website providing access to medical information for clinicians; the organization also provides continuing education for physicians and health professionals.
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Methadone
Methadone, sold under the brand name Dolophine among others, is an opioid used to treat pain and as maintenance therapy or to help with tapering in people with opioid dependence.
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Methamphetamine
Methamphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity.
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Methaqualone
Methaqualone, sold under the brand name Quaalude (pronounced) and sometimes stylized "Quāālude" in the United States and Mandrax in the United Kingdom and South Africa, is a sedative and hypnotic medication.
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Methocarbamol
Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.
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Methylenedioxyamphetamine
Methylenedioxyamphetamine may refer to.
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Michael Jackson
Michael Joseph Jackson (August 29, 1958 – June 25, 2009) was an American singer, songwriter, and dancer.
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Miss Elizabeth
Elizabeth Ann Hulette (November 19, 1960 – May 1, 2003), best known in professional wrestling circles as Miss Elizabeth, was an American professional wrestling manager and occasional professional wrestler.
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Mitch Hedberg
Mitchell Lee "Mitch" Hedberg (February 24, 1968 – March 30, 2005) was an American stand-up comedian known for his surreal humor and unconventional, often deadpan comedic delivery.
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Morphine
Morphine is a pain medication of the opiate variety which is found naturally in a number of plants and animals.
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MSNBC
MSNBC is an American news cable and satellite television network that provides news coverage and political commentary from NBC News on current events.
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MTV
MTV (originally an initialism of Music Television) is an American cable and satellite television channel owned by Viacom Media Networks (a division of Viacom) and headquartered in New York City.
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New York Rangers
The New York Rangers are a professional ice hockey team based in New York City.
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Nick Adams (actor, born 1931)
Nick Adams (born Nicholas Aloysius Adamshock, July 10, 1931 – February 7, 1968) was an American film and television actor and screenwriter.
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Nordazepam
Nordazepam (INN; marketed under brand names Nordaz, Stilny, Madar, Vegesan, and Calmday; also known as nordiazepam, desoxydemoxepam, and desmethyldiazepam) is a 1,4-benzodiazepine derivative.
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Ol' Dirty Bastard
Russell Tyrone Jones (November 15, 1968 – November 13, 2004), better known under his stage name Ol' Dirty Bastard (or ODB), was an American rapper and producer.
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Opioid
Opioids are substances that act on opioid receptors to produce morphine-like effects.
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Oseltamivir
Oseltamivir, sold under the brand name Tamiflu, is an antiviral medication used to treat and prevent influenza A and influenza B (flu).
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Osteopathic medicine
Osteopathic medicine is a branch of the medical profession practiced primarily in the United States, but has also spread into other countries, notably Canada.
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Over-the-counter drug
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a prescription from a healthcare professional, as opposed to prescription drugs, which may be sold only to consumers possessing a valid prescription.
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Oxazepam
Oxazepam is a short-to-intermediate-acting benzodiazepine.
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Oxycodone
Oxycodone, sold under brand names such as Percocet and OxyContin among many others, is an opioid medication which is used for the relief of moderate to severe pain.
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Oxycodone/paracetamol
The combination oxycodone/paracetamol (North American trade name Percocet, generic Endocet and Ratio-Oxycocet in Canada) is a combined opioid/non-opioid pain reliever used to treat moderate to severe acute (short-term) pain, marketed by Endo International plc, formerly Endo Pharmaceuticals.
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Oxygen
Oxygen is a chemical element with symbol O and atomic number 8.
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Oxymorphone
Oxymorphone, sold under the brand names Numorphan among others, is a powerful semi-synthetic opioid analgesic (painkiller) developed in Germany in 1914.
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Paracetamol
--> Acetanilide was the first aniline derivative serendipitously found to possess analgesic as well as antipyretic properties, and was quickly introduced into medical practice under the name of Antifebrin by A. Cahn and P. Hepp in 1886. But its unacceptable toxic effects, the most alarming being cyanosis due to methemoglobinemia, prompted the search for less toxic aniline derivatives. Harmon Northrop Morse had already synthesised paracetamol at Johns Hopkins University via the reduction of ''p''-nitrophenol with tin in glacial acetic acid in 1877, but it was not until 1887 that clinical pharmacologist Joseph von Mering tried paracetamol on humans. In 1893, von Mering published a paper reporting on the clinical results of paracetamol with phenacetin, another aniline derivative. Von Mering claimed that, unlike phenacetin, paracetamol had a slight tendency to produce methemoglobinemia. Paracetamol was then quickly discarded in favor of phenacetin. The sales of phenacetin established Bayer as a leading pharmaceutical company. Overshadowed in part by aspirin, introduced into medicine by Heinrich Dreser in 1899, phenacetin was popular for many decades, particularly in widely advertised over-the-counter "headache mixtures", usually containing phenacetin, an aminopyrine derivative of aspirin, caffeine, and sometimes a barbiturate. Paracetamol is the active metabolite of phenacetin and acetanilide, both once popular as analgesics and antipyretics in their own right. However, unlike phenacetin, acetanilide and their combinations, paracetamol is not considered carcinogenic at therapeutic doses. Von Mering's claims remained essentially unchallenged for half a century, until two teams of researchers from the United States analyzed the metabolism of acetanilide and paracetamol. In 1947 David Lester and Leon Greenberg found strong evidence that paracetamol was a major metabolite of acetanilide in human blood, and in a subsequent study they reported that large doses of paracetamol given to albino rats did not cause methemoglobinemia. In three papers published in the September 1948 issue of the Journal of Pharmacology and Experimental Therapeutics, Bernard Brodie, Julius Axelrod and Frederick Flinn confirmed using more specific methods that paracetamol was the major metabolite of acetanilide in human blood, and established that it was just as efficacious an analgesic as its precursor. They also suggested that methemoglobinemia is produced in humans mainly by another metabolite, phenylhydroxylamine. A follow-up paper by Brodie and Axelrod in 1949 established that phenacetin was also metabolised to paracetamol. This led to a "rediscovery" of paracetamol. It has been suggested that contamination of paracetamol with 4-aminophenol, the substance von Mering synthesised it from, may be the cause for his spurious findings. Paracetamol was first marketed in the United States in 1950 under the name Triagesic, a combination of paracetamol, aspirin, and caffeine. Reports in 1951 of three users stricken with the blood disease agranulocytosis led to its removal from the marketplace, and it took several years until it became clear that the disease was unconnected. Paracetamol was marketed in 1953 by Sterling-Winthrop Co. as Panadol, available only by prescription, and promoted as preferable to aspirin since it was safe for children and people with ulcers. In 1955, paracetamol was marketed as Children's Tylenol Elixir by McNeil Laboratories. In 1956, 500 mg tablets of paracetamol went on sale in the United Kingdom under the trade name Panadol, produced by Frederick Stearns & Co, a subsidiary of Sterling Drug Inc. In 1963, paracetamol was added to the British Pharmacopoeia, and has gained popularity since then as an analgesic agent with few side-effects and little interaction with other pharmaceutical agents. Concerns about paracetamol's safety delayed its widespread acceptance until the 1970s, but in the 1980s paracetamol sales exceeded those of aspirin in many countries, including the United Kingdom. This was accompanied by the commercial demise of phenacetin, blamed as the cause of analgesic nephropathy and hematological toxicity. In 1988 Sterling Winthrop was acquired by Eastman Kodak which sold the over the counter drug rights to SmithKline Beecham in 1994. Available without a prescription since 1959, it has since become a common household drug. Patents on paracetamol have long expired, and generic versions of the drug are widely available.
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Paraldehyde
Paraldehyde is the cyclic trimer of acetaldehyde molecules.
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Paul Gray (American musician)
Paul Dedrick Gray (April 8, 1973 – May 24, 2010), also known as The Pig or by his number #2, was an US-American musician best known as the former bassist, backing vocalist, songwriter and one of the founding members of the Grammy Award-winning metal band Slipknot.
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Persistent vegetative state
A persistent vegetative state (PVS) is a disorder of consciousness in which patients with severe brain damage are in a state of partial arousal rather than true awareness.
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Pethidine
Pethidine, also known as meperidine and sold under the brand name Demerol among others, is a synthetic opioid pain medication of the phenylpiperidine class.
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Pharmacology
Pharmacology is the branch of biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous (from within body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to encompass these endogenous and exogenous bioactive species).
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Pharmacovigilance
Pharmacovigilance (PV or PhV), also known as drug safety, is the pharmacological science relating to the collection, detection, assessment, monitoring, and prevention of adverse effects with pharmaceutical products.
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Phencyclidine
Phencyclidine (PCP), also known as angel dust among other names, is a drug used for its mind altering effects.
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Philip Seymour Hoffman
Philip Seymour Hoffman (July 23, 1967 – February 2, 2014) was an American actor, director, and producer.
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Physician
A physician, medical practitioner, medical doctor, or simply doctor is a professional who practises medicine, which is concerned with promoting, maintaining, or restoring health through the study, diagnosis, and treatment of disease, injury, and other physical and mental impairments.
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Pneumonia
Pneumonia is an inflammatory condition of the lung affecting primarily the small air sacs known as alveoli.
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Poly drug use
Poly drug use refers to the use of two or more psychoactive drugs in combination to achieve a particular effect.
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Polypharmacy
Polypharmacy is the concurrent use of multiple medications by a patient.
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Prescription drug
A prescription drug (also prescription medication or prescription medicine) is a pharmaceutical drug that legally requires a medical prescription to be dispensed.
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Promazine
Promazine (brand name Sparine) is a medication that belongs to the phenothiazine class of antipsychotics.
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Propofol
Propofol, marketed as Diprivan among others, is a short-acting medication that results in a decreased level of consciousness and lack of memory for events.
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Recreational drug use
Recreational drug use is the use of a psychoactive drug to induce an altered state of consciousness for pleasure, by modifying the perceptions, feelings, and emotions of the user.
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Respiratory failure
Respiratory failure results from inadequate gas exchange by the respiratory system, meaning that the arterial oxygen, carbon dioxide or both cannot be kept at normal levels.
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Right to die
The right to die is a concept based on the opinion that a human being is entitled to end his or her own life or to undergo voluntary euthanasia.
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River Phoenix
River Jude Phoenix (né Bottom; August 23, 1970 – October 31, 1993) was an American actor, musician, and activist.
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Robert F. Kennedy
Robert Francis "Bobby" Kennedy (November 20, 1925 – June 6, 1968) was an American politician and lawyer who served as the 64th United States Attorney General from January 1961 to September 1964, and as a U.S. Senator for New York from January 1965 until his assassination in June 1968.
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Rodney King
Rodney Glen King (April 2, 1965 – June 17, 2012) was an African-American taxi driver who became known internationally as the victim of Los Angeles Police Department brutality, after a videotape was released of several police officers beating him during his arrest on March 3, 1991.
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Scott Weiland
Scott Richard Weiland (né Kline, October 27, 1967 – December 3, 2015) was an American musician, singer and songwriter.
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Secobarbital
Secobarbital sodium (marketed by Eli Lilly and Company, and subsequently by other companies as described below, under the brand name Seconal) is a barbiturate derivative drug that was patented in 1934 in the United States.
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Sedative
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.
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Sertraline
Sertraline, sold under the trade names Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
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Slipknot (band)
Slipknot is an American heavy metal band from Des Moines, Iowa.
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SoHo, Manhattan
SoHo, sometimes written Soho, is a neighborhood in Lower Manhattan, New York City, which in recent history came to the public's attention for being the location of many artists' lofts and art galleries, but is now better known for its variety of shops ranging from trendy upscale boutiques to national and international chain store outlets.
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Speedball (drug)
Speedball (or powerball) is a mix of cocaine with heroin or morphine taken intravenously or by insufflation.
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Steve Clark
Stephen Maynard Clark (23 April 1960 – 8 January 1991) was an English musician.
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Stone Temple Pilots
Stone Temple Pilots (often abbreviated as STP) are an American rock band from San Diego, California, that originally consisted of Scott Weiland (lead vocals), brothers Robert DeLeo (bass, backing vocals) and Dean DeLeo (guitars), and Eric Kretz (drums).
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Substance abuse
Substance abuse, also known as drug abuse, is a patterned use of a drug in which the user consumes the substance in amounts or with methods which are harmful to themselves or others, and is a form of substance-related disorder.
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Substituted amphetamine
Substituted amphetamines are a class of compounds based upon the amphetamine structure; it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents.
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Supreme Court of New Jersey
The Supreme Court of New Jersey is the highest court in the U.S. state of New Jersey.
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Temazepam
Temazepam (brand names Restoril and Normison, among others) is an intermediate-acting 3-hydroxy hypnotic of the benzodiazepine class of psychoactive drugs.
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The Age
The Age is a daily newspaper that has been published in Melbourne, Australia, since 1854.
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The New York Times
The New York Times (sometimes abbreviated as The NYT or The Times) is an American newspaper based in New York City with worldwide influence and readership.
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The Rev
James Owen Sullivan (February 9, 1981 – December 28, 2009), professionally known by his stage name The Rev (shortened version of The Reverend Tholomew Plague), was an American musician, best known as the drummer, songwriter, co-lead vocalist and founding member for the American heavy metal band Avenged Sevenfold.
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Theraflu
Theraflu is a brand of over-the-counter cold and flu medicines from GSK Consumer Healthcare that contain different groupings of various cold and flu symptom medications.
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Thioridazine
Thioridazine (Mellaril or Melleril) is a piperidine typical antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis.
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Ticketmaster
Ticketmaster Entertainment, Inc. is an American ticket sales and distribution company based in Beverly Hills, California, with operations in many countries around the world.
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Tommy Bolin
Thomas Richard Bolin (August 1, 1951 – December 4, 1976) was an American guitarist and songwriter who played with Zephyr (from 1969 to 1971), James Gang (from 1973 through 1974), and Deep Purple (from 1975 to 1976), in addition to maintaining a notable career as a solo artist and session musician.
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Topiramate
Topiramate (brand name Topamax) is an anticonvulsant (antiepilepsy) drug.
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Toxicity
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.
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Toxicology
Toxicology is a discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants.
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Tramadol
Tramadol, sold under the brand name Ultram among others, is an opioid pain medication used to treat moderate to moderately severe pain.
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Trevor Goddard
Trevor Joseph Goddard (14 October 1962 – 7 June 2003) was an English actor.
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Truman Capote
Truman Garcia Capotehttp://www.biography.com/people/truman-capote-9237547#early-life (born Truman Streckfus Persons, September 30, 1924 – August 25, 1984) was an American novelist, short story writer, screenwriter, playwright, and actor.
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University of California, San Diego
The University of California, San Diego is a public research university located in the La Jolla neighborhood of San Diego, California, in the United States.
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Unnatural death
Unnatural death is a category used by coroners or medical examiners and vital statistics specialists for classifying all human deaths not properly describable as death by natural causes.
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USA Today
USA Today is an internationally distributed American daily, middle-market newspaper that serves as the flagship publication of its owner, the Gannett Company.
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Velvet Revolver
Velvet Revolver was an American hard rock supergroup consisting of Guns N' Roses members Slash (lead guitar), Duff McKagan (bass, backing vocals), and former member Matt Sorum (drums, backing vocals), alongside Dave Kushner (rhythm guitar) formerly of punk band Wasted Youth and Scott Weiland formerly of Stone Temple Pilots.
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Vicks
Vicks is an American brand of over-the-counter medications owned by the American company Procter & Gamble.
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Whitney Houston
Whitney Elizabeth Houston (August 9, 1963 – February 11, 2012) was an American singer and actress.
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World Wide Web
The World Wide Web (abbreviated WWW or the Web) is an information space where documents and other web resources are identified by Uniform Resource Locators (URLs), interlinked by hypertext links, and accessible via the Internet.
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Wu-Tang Clan
Wu-Tang Clan is an American hip hop group from Staten Island, New York City, originally composed of East Coast rappers RZA, GZA, Ol' Dirty Bastard, Method Man, Raekwon, Ghostface Killah, Inspectah Deck, U-God and Masta Killa.
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20/20 (U.S. TV series)
20/20 is an American television newsmagazine that has been broadcast on ABC since June 6, 1978.
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Redirects here:
Combined Drug Intoxication, Mixed drug intoxication, Multiple Drug Intake, Multiple drug intake.
References
[1] https://en.wikipedia.org/wiki/Combined_drug_intoxication
