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Glycan

Index Glycan

The terms glycan and polysaccharide are defined by IUPAC as synonyms meaning "compounds consisting of a large number of monosaccharides linked glycosidically". [1]

90 relations: ABO blood group system, Affinity chromatography, Affinity electrophoresis, Asparagine, Azide, Calnexin, Calreticulin, Capillary electrophoresis, Carbohydrate, Cell membrane, Chaperone (protein), Chondroitin, Chromatography, Consortium for Functional Glycomics, Cysteine, Cytoplasm, Dental plaque, Dermatan sulfate, Dolichol monophosphate, Electrophoresis, Electrospray ionization, Endoplasmic reticulum, Enzyme, Eukaryote, Extravasation, Factor IX, Factor VII, Fucose, Galactose, Glucan, Glycan, Glycoconjugate, Glycolipid, Glycophorin, Glycoprotein, Glycosaminoglycan, Glycoside, Glycoside hydrolase, Glycosidic bond, Glycosylation, Glycosylphosphatidylinositol, Glycosyltransferase, Golgi apparatus, Heparan sulfate, Heparin, High-performance liquid chromatography, International Union of Pure and Applied Chemistry, Keratan sulfate, Lectin, Lysosome, ..., Mannose, Mannose 6-phosphate, Mannose 6-phosphate receptor, Mass spectrometry, Matrix-assisted laser desorption/ionization, Monoclonal antibody, Monosaccharide, Mucin, N-Acetylgalactosamine, N-Acetylglucosamine, National Academies of Sciences, Engineering, and Medicine, Natural killer cell, Nature Publishing Group, Neuraminic acid, Notch signaling pathway, Nuclear magnetic resonance spectroscopy of proteins, Oligosaccharide, Oligosaccharyltransferase, Peptidoglycan, Plasminogen activator, Polyacrylamide gel electrophoresis, Polysaccharide, Prokaryote, Proline, Proteoglycan, Red blood cell, Saliva, Selectin, Sequon, Serine, Sialic acid, Sialyl-Lewis X, Staudinger reaction, Sugar, Swiss Institute of Bioinformatics, Threonine, Thrombospondin, Uronic acid, Weibel–Palade body, X-ray crystallography. Expand index (40 more) »

ABO blood group system

The ABO blood group system is used to denote the presence of one, both, or neither of the A and B antigens on erythrocytes.

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Affinity chromatography

Affinity chromatography is a method of separating biochemical mixtures based on a highly specific interaction between antigen and antibody, enzyme and substrate, receptor and ligand, or protein and nucleic acid.

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Affinity electrophoresis

Affinity electrophoresis is a general name for many analytical methods used in biochemistry and biotechnology.

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Asparagine

Asparagine (symbol Asn or N), is an α-amino acid that is used in the biosynthesis of proteins.

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Azide

Azide is the anion with the formula N. It is the conjugate base of hydrazoic acid (HN3).

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Calnexin

Calnexin (CNX) is a integral protein (that appears variously as a 90kDa, 80kDa, or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER).

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Calreticulin

Calreticulin also known as calregulin, CRP55, CaBP3, calsequestrin-like protein, and endoplasmic reticulum resident protein 60 (ERp60) is a protein that in humans is encoded by the CALR gene.

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Capillary electrophoresis

Capillary electrophoresis (CE) is a family of electrokinetic separation methods performed in submillimeter diameter capillaries and in micro- and nanofluidic channels.

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Carbohydrate

A carbohydrate is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water); in other words, with the empirical formula (where m may be different from n).

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Chaperone (protein)

In molecular biology, molecular chaperones are proteins that assist the covalent folding or unfolding and the assembly or disassembly of other macromolecular structures.

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Chondroitin

Chondroitin is a chondrin derivative.

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Chromatography

Chromatography is a laboratory technique for the separation of a mixture.

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Consortium for Functional Glycomics

The Consortium for Functional Glycomics (CFG) is a large research initiative funded in 2001 by a glue grant from the National Institute of General Medical Sciences (NIGMS) to “define paradigms by which protein-carbohydrate interactions mediate cell communication”.

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Cysteine

Cysteine (symbol Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.

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Cytoplasm

In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.

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Dental plaque

Dental plaque is a biofilm or mass of bacteria that grows on surfaces within the mouth.

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Dermatan sulfate

Dermatan sulfate is a glycosaminoglycan (formerly called a mucopolysaccharide) found mostly in skin, but also in blood vessels, heart valves, tendons, and lungs.

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Dolichol monophosphate

Dolichol monophosphate is a fatty alcohol.

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Electrophoresis

Electrophoresis (from the Greek "Ηλεκτροφόρηση" meaning "to bear electrons") is the motion of dispersed particles relative to a fluid under the influence of a spatially uniform electric field.

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Electrospray ionization

Electrospray ionization (ESI) is a technique used in mass spectrometry to produce ions using an electrospray in which a high voltage is applied to a liquid to create an aerosol.

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Endoplasmic reticulum

The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Eukaryote

Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

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Extravasation

Extravasation is the leakage of a fluid out of its container.

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Factor IX

Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1.

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Factor VII

Factor VII (blood-coagulation factor VIIa, activated blood coagulation factor VII, formerly known as proconvertin) is one of the proteins that causes blood to clot in the coagulation cascade.

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Fucose

Fucose is a hexose deoxy sugar with the chemical formula C6H12O5.

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Galactose

Galactose (galacto- + -ose, "milk sugar"), sometimes abbreviated Gal, is a monosaccharide sugar that is about as sweet as glucose, and about 30% as sweet as sucrose.

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Glucan

A glucan molecule is a polysaccharide of D-glucose monomers, linked by glycosidic bonds.

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Glycan

The terms glycan and polysaccharide are defined by IUPAC as synonyms meaning "compounds consisting of a large number of monosaccharides linked glycosidically".

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Glycoconjugate

Glycoconjugates is the general classification for carbohydrates covalently linked with other chemical species such as proteins, peptides, lipids and saccharides.

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Glycolipid

Glycolipids are lipids with a carbohydrate attached by a glycosidic bond or covalently bonded.

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Glycophorin

A glycophorin is a sialoglycoprotein of the membrane of a red blood cell.

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Glycoprotein

Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.

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Glycosaminoglycan

Glycosaminoglycans (GAGs) or mucopolysaccharides are long unbranched polysaccharides consisting of a repeating disaccharide unit.

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Glycoside

In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond.

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Glycoside hydrolase

Glycoside hydrolases (also called glycosidases or glycosyl hydrolases) catalyze the hydrolysis of glycosidic bonds in complex sugars.

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Glycosidic bond

In chemistry, a glycosidic bond or glycosidic linkage is a type of covalent bond that joins a carbohydrate (sugar) molecule to another group, which may or may not be another carbohydrate.

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Glycosylation

Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor).

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Glycosylphosphatidylinositol

Glycosylphosphatidylinositol, or glycophosphatidylinositol, or GPI in short, is a glycolipid that can be attached to the C-terminus of a protein during posttranslational modification.

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Glycosyltransferase

Glycosyltransferases (GTFs, Gtfs) are enzymes (EC 2.4) that establish natural glycosidic linkages.

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Golgi apparatus

The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells.

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Heparan sulfate

Heparan sulfate (HS) is a linear polysaccharide found in all animal tissues.

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Heparin

Heparin, also known as unfractionated heparin (UFH), is medication which is used as an anticoagulant (blood thinner).

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High-performance liquid chromatography

High-performance liquid chromatography (HPLC; formerly referred to as high-pressure liquid chromatography), is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture.

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International Union of Pure and Applied Chemistry

The International Union of Pure and Applied Chemistry (IUPAC) is an international federation of National Adhering Organizations that represents chemists in individual countries.

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Keratan sulfate

Keratan sulfate (KS), also called keratosulfate, is any of several sulfated glycosaminoglycans (structural carbohydrates) that have been found especially in the cornea, cartilage, and bone.

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Lectin

Lectins are carbohydrate-binding proteins, macromolecules that are highly specific for sugar moieties of other molecules.

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Lysosome

A lysosome is a membrane-bound organelle found in nearly all animal cells.

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Mannose

Mannose, packaged as the nutritional supplement "d-mannose", is a sugar monomer of the aldohexose series of carbohydrates.

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Mannose 6-phosphate

Mannose-6-phosphate (M6P) is a molecule bound by lectin in the immune system.

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Mannose 6-phosphate receptor

The mannose 6-phosphate receptors (MPRs) are transmembrane glycoproteins that target enzymes to lysosomes in vertebrates.

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Mass spectrometry

Mass spectrometry (MS) is an analytical technique that ionizes chemical species and sorts the ions based on their mass-to-charge ratio.

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Matrix-assisted laser desorption/ionization

In mass spectrometry, matrix-assisted laser desorption/ionization (MALDI) is an ionization technique that uses a laser energy absorbing matrix to create ions from large molecules with minimal fragmentation.

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Monoclonal antibody

Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.

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Monosaccharide

Monosaccharides (from Greek monos: single, sacchar: sugar), also called simple sugars, are the most basic units of carbohydrates.

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Mucin

Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most animals.

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N-Acetylgalactosamine

N-Acetylgalactosamine (GalNAc), is an amino sugar derivative of galactose.

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N-Acetylglucosamine

N-Acetylglucosamine (N-acetyl-D-glucosamine, or GlcNAc, or NAG) is a monosaccharide and a derivative of glucose.

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National Academies of Sciences, Engineering, and Medicine

The National Academies of Sciences, Engineering, and Medicine (also known as "NASEM" or "the National Academies") is the collective scientific national academy of the United States.

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Natural killer cell

Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.

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Nature Publishing Group

Nature Publishing Group is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in science and medicine.

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Neuraminic acid

Neuraminic acid (5-amino-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid) is a 9-carbon monosaccharide (a nonose), a derivative of a ketononose.

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Notch signaling pathway

The Notch signaling pathway is a highly conserved cell signaling system present in most multicellular organisms.

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Nuclear magnetic resonance spectroscopy of proteins

Nuclear magnetic resonance spectroscopy of proteins (usually abbreviated protein NMR) is a field of structural biology in which NMR spectroscopy is used to obtain information about the structure and dynamics of proteins, and also nucleic acids, and their complexes.

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Oligosaccharide

An oligosaccharide (from the Greek ὀλίγος olígos, "a few", and σάκχαρ sácchar, "sugar") is a saccharide polymer containing a small number (typically three to ten) of monosaccharides (simple sugars).

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Oligosaccharyltransferase

Oligosaccharyltransferase or OST is a membrane protein complex that transfers a 14-sugar oligosaccharide from dolichol to nascent protein.

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Peptidoglycan

Peptidoglycan, also known as murein, is a polymer consisting of sugars and amino acids that forms a mesh-like layer outside the plasma membrane of most bacteria, forming the cell wall.

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Plasminogen activator

Plasminogen activators are serine proteases that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen.

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Polyacrylamide gel electrophoresis

Polyacrylamide gel electrophoresis (PAGE) is a technique widely used in biochemistry, forensic chemistry, genetics, molecular biology and biotechnology to separate biological macromolecules, usually proteins or nucleic acids, according to their electrophoretic mobility.

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Polysaccharide

Polysaccharides are polymeric carbohydrate molecules composed of long chains of monosaccharide units bound together by glycosidic linkages, and on hydrolysis give the constituent monosaccharides or oligosaccharides.

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Prokaryote

A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.

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Proline

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins.

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Proteoglycan

Proteoglycans are proteins that are heavily glycosylated.

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Red blood cell

Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.

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Saliva

Saliva is a watery substance formed in the mouths of animals, secreted by the salivary glands.

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Selectin

The selectins (cluster of differentiation 62 or CD62) are a family of cell adhesion molecules (or CAMs).

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Sequon

A sequon is a sequence of consecutive amino acids in a protein that can serve as the attachment site to a polysaccharide, frequently an N-linked-Glycan.

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Serine

Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins.

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Sialic acid

Sialic acid is a generic term for the N- or O-substituted derivatives of neuraminic acid, a monosaccharide with a nine-carbon backbone.

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Sialyl-Lewis X

Sialyl LewisX, also known as sialyl LeX or SLeX, is a tetrasaccharide carbohydrate with the sequence Neu5Acα2-3Galβ1-4GlcNAcβ- that is usually attached to O-glycans on the surface of cells.

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Staudinger reaction

The Staudinger reaction is a chemical reaction of an azide with a phosphine or phosphite produces an iminophosphorane.

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Sugar

Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food.

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Swiss Institute of Bioinformatics

The SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation which federates bioinformatics activities throughout Switzerland.

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Threonine

Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.

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Thrombospondin

Thrombospondins are a family of secreted glycoproteins with antiangiogenic functions.

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Uronic acid

The Fischer projections of glucose and glucuronic acid. Glucose's terminal carbon's primary alcohol group has been oxidized to a carboxylic acid. Uronic acids are a class of sugar acids with both carbonyl and carboxylic acid functional groups.

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Weibel–Palade body

Weibel–Palade bodies are the storage granules of endothelial cells, the cells that form the inner lining of the blood vessels and heart.

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X-ray crystallography

X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.

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Redirects here:

Glycans, N-linked Glycan, N-linked glycan, N-linked-Glycan.

References

[1] https://en.wikipedia.org/wiki/Glycan

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