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Ketamine and Phencyclidine

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between Ketamine and Phencyclidine

Ketamine vs. Phencyclidine

Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia. Phencyclidine (PCP), also known as angel dust among other names, is a drug used for its mind altering effects.

Similarities between Ketamine and Phencyclidine

Ketamine and Phencyclidine have 50 things in common (in Unionpedia): Allosteric regulation, Amnesia, Analgesic, Anesthesia, Anticholinergic, Arylcyclohexylamine, Benzodiazepine, Conditioned place preference, Delirium, Depersonalization, Dextromethorphan, Dissociative, Dizocilpine, Dopamine, Dopamine receptor D2, Erythema, Eticyclidine, Euphoria, Free base, Hallucination, IC50, Insufflation (medicine), Intramuscular injection, Ionotropic glutamate receptor, Ketamine, Ligand (biochemistry), Misuse of Drugs Act 1971, Monoamine reuptake inhibitor, Monoamine transporter, Neurotransmission, ..., Neurotransmitter receptor, Neurotransmitter transporter, Nicotinic acetylcholine receptor, NMDA receptor, NMDA receptor antagonist, Nystagmus, Olney's lesions, Oral administration, Parke-Davis, Partial agonist, PCP site 2, Pharmacodynamics, Phenothiazine, Recreational drug use, Sigma-1 receptor, Sigma-2 receptor, Suicidal ideation, Tenocyclidine, Tiletamine, 5-HT2A receptor. Expand index (20 more) »

Allosteric regulation

In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule at a site other than the enzyme's active site.

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Amnesia

Amnesia is a deficit in memory caused by brain damage, disease, or psychological trauma.

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Analgesic

An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.

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Anesthesia

In the practice of medicine (especially surgery and dentistry), anesthesia or anaesthesia (from Greek "without sensation") is a state of temporary induced loss of sensation or awareness.

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Anticholinergic

An anticholinergic agent is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system.

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Arylcyclohexylamine

Arylcyclohexylamines, also known as arylcyclohexamines or arylcyclohexanamines, are a chemical class of pharmaceutical, designer, and experimental drugs.

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Benzodiazepine

Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

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Conditioned place preference

Conditioned place preference (CPP) is a form of Pavlovian conditioning used to measure the motivational effects of objects or experiences.

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Delirium

Delirium, also known as acute confusional state, is an organically caused decline from a previously baseline level of mental function.

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Depersonalization

Depersonalization can consist of a detachment within the self, regarding one's mind or body, or being a detached observer of oneself.

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Dextromethorphan

Dextromethorphan (DXM or DM) is a drug of the morphinan class with sedative, dissociative, and stimulant properties (at higher doses).

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Dissociative

Dissociatives are a class of hallucinogen, which distort perceptions of sight and sound and produce feelings of detachment – dissociation – from the environment and self.

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Dizocilpine

Dizocilpine (INN), also known as MK-801, is a noncompetitive antagonist of the ''N''-Methyl-D-aspartate (NMDA) receptor, a glutamate receptor, discovered by a team at Merck in 1982.

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Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

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Dopamine receptor D2

Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.

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Erythema

Erythema (from the Greek erythros, meaning red) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries.

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Eticyclidine

Eticyclidine (PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects.

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Euphoria

Euphoria is an affective state in which a person experiences pleasure or excitement and intense feelings of well-being and happiness.

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Free base

Free base (freebase, free-base) is the conjugate base (deprotonated) form of an amine, as opposed to its conjugate acid (protonated) form.

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Hallucination

A hallucination is a perception in the absence of external stimulus that has qualities of real perception.

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IC50

The half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.

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Insufflation (medicine)

Insufflation (lit) is the act of blowing something (such as a gas, powder, or vapor) into a body cavity.

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Intramuscular injection

Intramuscular (also IM or im) injection is the injection of a substance directly into muscle.

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Ionotropic glutamate receptor

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.

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Ketamine

Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Misuse of Drugs Act 1971

The Misuse of Drugs Act 1971 is an Act of the Parliament of the United Kingdom.

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Monoamine reuptake inhibitor

A monoamine reuptake inhibitor (MRI) is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin, norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).

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Monoamine transporter

Monoamine transporters (MATs) are protein structures that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters.

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Neurotransmission

Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through"), also called synaptic transmission, is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and activate the receptors on the dendrites of another neuron (the postsynaptic neuron).

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Neurotransmitter receptor

A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter.

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Neurotransmitter transporter

Neurotransmitter transporters are a class of membrane transport proteins that span the cellular membranes of neurons.

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Nicotinic acetylcholine receptor

Nicotinic acetylcholine receptors, or nAChRs, are receptor proteins that respond to the neurotransmitter acetylcholine.

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NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and ion channel protein found in nerve cells.

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NMDA receptor antagonist

NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the ''N''-Methyl-D-aspartate receptor (NMDAR).

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Nystagmus

Nystagmus is a condition of involuntary (or voluntary, in rare cases) eye movement, acquired in infancy or later in life, that may result in reduced or limited vision.

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Olney's lesions

Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAN), are a potential form of brain damage due to drugs that have been studied experimentally and have produced neuronal damage, yet are administered by doctors to humans in the settings of pharmacotherapy and of anesthesia.

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Oral administration

| name.

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Parke-Davis

Parke-Davis is a subsidiary of the pharmaceutical company Pfizer.

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Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

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PCP site 2

PCP site 2 is a binding site that was identified as a high-affinity target for phencyclidine (PCP), an anesthetic and dissociative hallucinogen that acts primarily as an NMDA receptor antagonist.

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Pharmacodynamics

Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).

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Phenothiazine

Phenothiazine, abbreviated PTZ, is an organic compound that has the formula S(C6H4)2NH and is related to the thiazine-class of heterocyclic compounds.

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Recreational drug use

Recreational drug use is the use of a psychoactive drug to induce an altered state of consciousness for pleasure, by modifying the perceptions, feelings, and emotions of the user.

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Sigma-1 receptor

The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor.

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Sigma-2 receptor

The sigma-2 receptor (σ2R) is a sigma receptor subtype that has been found highly expressed in malignant cancer cells, and is currently under investigation for its potential diagnostic and therapeutic uses.

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Suicidal ideation

Suicidal ideation, also known as suicidal thoughts, is thinking about or having an unusual preoccupation with suicide.

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Tenocyclidine

Tenocyclidine (TCP) was discovered by a team at Parke-Davis in the late 1950s.

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Tiletamine

Tiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist.

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5-HT2A receptor

The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).

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The list above answers the following questions

Ketamine and Phencyclidine Comparison

Ketamine has 386 relations, while Phencyclidine has 144. As they have in common 50, the Jaccard index is 9.43% = 50 / (386 + 144).

References

This article shows the relationship between Ketamine and Phencyclidine. To access each article from which the information was extracted, please visit:

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