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Ketamine

Index Ketamine

Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. [1]

Table of Contents

  1. 266 relations: Acute kidney injury, Adam Parfrey, Advisory Council on the Misuse of Drugs, Albendazole, Allosteric regulation, Alpha-3 beta-2 nicotinic receptor, Alpha-3 beta-4 nicotinic receptor, Alpha-4 beta-2 nicotinic receptor, Alpha-7 nicotinic receptor, Amnesia, Analgesic, Anesthesia, Anterograde amnesia, Anthelmintic, Anticholinergic, Antidepressant, Arketamine, Arylcyclohexylamine, Asthma, Australia, Benzodiazepine, Biliary colic, Bioavailability, Biotransformation, Bipolar disorder, Blood pressure, Botulinum toxin, Brain-derived neurotrophic factor, Bromine, Bromocriptine, Bronchodilator, Bronchospasm, Cachexia, Calvin L. Stevens, Canada, Canada Gazette, Cardiovascular disease, Case report, Cell signaling, Centre for Addiction and Mental Health, Cerebrospinal fluid, Chirality (chemistry), Chronic obstructive pulmonary disease, Chronic pain, Circulatory system, Cirrhosis, Clonidine, Clonus, Cochrane (organisation), Complex regional pain syndrome, ... Expand index (216 more) »

  2. Chemical substances for emergency medicine
  3. D2-receptor agonists
  4. Drug-facilitated sexual assault
  5. Equine medications
  6. Opioid modulators

Acute kidney injury

Acute kidney injury (AKI), previously called acute renal failure (ARF), is a sudden decrease in kidney function that develops within 7 days, as shown by an increase in serum creatinine or a decrease in urine output, or both.

See Ketamine and Acute kidney injury

Adam Parfrey

Adam Parfrey (April 12, 1957 – May 10, 2018) was an American journalist, editor, and the publisher of Feral House books, whose work in all three capacities frequently centered on unusual, extreme, or "forbidden" areas of knowledge.

See Ketamine and Adam Parfrey

Advisory Council on the Misuse of Drugs

The Advisory Council on the Misuse of Drugs (ACMD) is a British statutory advisory non-departmental public body, which was established under the Misuse of Drugs Act 1971.

See Ketamine and Advisory Council on the Misuse of Drugs

Albendazole

Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. Ketamine and Albendazole are world Health Organization essential medicines.

See Ketamine and Albendazole

Allosteric regulation

In the fields of biochemistry and pharmacology an allosteric regulator (or allosteric modulator) is a substance that binds to a site on an enzyme or receptor distinct from the active site, resulting in a conformational change that alters the protein's activity, either enhancing or inhibiting its function.

See Ketamine and Allosteric regulation

Alpha-3 beta-2 nicotinic receptor

The alpha-3 beta-2 nicotinic receptor, also known as the α3β2 receptor, is a type of nicotinic acetylcholine receptor, consisting of α3 and β2 subunits.

See Ketamine and Alpha-3 beta-2 nicotinic receptor

Alpha-3 beta-4 nicotinic receptor

The alpha-3 beta-4 nicotinic receptor, also known as the α3β4 receptor and the ganglion-type nicotinic receptor,Pharmacology, (Rang, Dale, Ritter & Moore,, 5th ed., Churchill Livingstone 2003) p. 138.

See Ketamine and Alpha-3 beta-4 nicotinic receptor

Alpha-4 beta-2 nicotinic receptor

The alpha-4 beta-2 nicotinic receptor, also known as the α4β2 receptor, is a type of nicotinic acetylcholine receptor implicated in learning, consisting of α4 and β2 subunits.

See Ketamine and Alpha-4 beta-2 nicotinic receptor

Alpha-7 nicotinic receptor

The alpha-7 nicotinic receptor, also known as the α7 receptor, is a type of nicotinic acetylcholine receptor implicated in long-term memory, consisting entirely of α7 subunits.

See Ketamine and Alpha-7 nicotinic receptor

Amnesia

Amnesia is a deficit in memory caused by brain damage or brain diseases,Gazzaniga, M., Ivry, R., & Mangun, G. (2009) Cognitive Neuroscience: The biology of the mind.

See Ketamine and Amnesia

Analgesic

An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management. Ketamine and analgesic are analgesics.

See Ketamine and Analgesic

Anesthesia

Anesthesia or anaesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes.

See Ketamine and Anesthesia

Anterograde amnesia

In neurology, anterograde amnesia is the inability to create new memories after an event that caused amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact.

See Ketamine and Anterograde amnesia

Anthelmintic

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host.

See Ketamine and Anthelmintic

Anticholinergic

Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system.

See Ketamine and Anticholinergic

Antidepressant

Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction. Ketamine and Antidepressant are antidepressants.

See Ketamine and Antidepressant

Arketamine

Arketamine (developmental code names PCN-101, HR-071603), also known as (R)-ketamine or (R)-(&minus)-ketamine, is the (R)-(&minus) enantiomer of ketamine. Ketamine and Arketamine are Arylcyclohexylamines, Chloroarenes, dissociative drugs, general anesthetics, ketones, muscarinic antagonists, NMDA receptor antagonists, nicotinic antagonists, sedatives and sigma agonists.

See Ketamine and Arketamine

Arylcyclohexylamine

Arylcyclohexylamines, also known as arylcyclohexamines or arylcyclohexanamines, are a chemical class of pharmaceutical, designer, and experimental drugs. Ketamine and Arylcyclohexylamine are Arylcyclohexylamines, general anesthetics and NMDA receptor antagonists.

See Ketamine and Arylcyclohexylamine

Asthma

Asthma is a long-term inflammatory disease of the airways of the lungs.

See Ketamine and Asthma

Australia

Australia, officially the Commonwealth of Australia, is a country comprising the mainland of the Australian continent, the island of Tasmania, and numerous smaller islands.

See Ketamine and Australia

Benzodiazepine

Benzodiazepines (BZD, BDZ, BZs), colloquially called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. Ketamine and Benzodiazepine are sedatives.

See Ketamine and Benzodiazepine

Biliary colic

Biliary colic, also known as symptomatic cholelithiasis, a gallbladder attack or gallstone attack, is when a colic (sudden pain) occurs due to a gallstone temporarily blocking the cystic duct.

See Ketamine and Biliary colic

Bioavailability

In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.

See Ketamine and Bioavailability

Biotransformation

Biotransformation is the biochemical modification of one chemical compound or a mixture of chemical compounds.

See Ketamine and Biotransformation

Bipolar disorder

Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that each last from days to weeks.

See Ketamine and Bipolar disorder

Blood pressure

Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels.

See Ketamine and Blood pressure

Botulinum toxin

Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum and related species.

See Ketamine and Botulinum toxin

Brain-derived neurotrophic factor

Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein found in the and the periphery.

See Ketamine and Brain-derived neurotrophic factor

Bromine

Bromine is a chemical element; it has symbol Br and atomic number 35.

See Ketamine and Bromine

Bromocriptine

Bromocriptine, originally marketed as Parlodel and subsequently under many brand names, is an ergoline derivative and dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease, hyperprolactinaemia, neuroleptic malignant syndrome, and, as an adjunct, type 2 diabetes.

See Ketamine and Bromocriptine

Bronchodilator

A bronchodilator or broncholytic (although the latter occasionally includes secretory inhibition as well) is a substance that dilates the bronchi and bronchioles, decreasing resistance in the respiratory airway and increasing airflow to the lungs.

See Ketamine and Bronchodilator

Bronchospasm

Bronchospasm or a bronchial spasm is a sudden constriction of the muscles in the walls of the bronchioles.

See Ketamine and Bronchospasm

Cachexia

Cachexia is a complex syndrome associated with an underlying illness, causing ongoing muscle loss that is not entirely reversed with nutritional supplementation.

See Ketamine and Cachexia

Calvin L. Stevens

Calvin Lee Stevens (November 3, 1923 – November 26, 2014) was an American chemist.

See Ketamine and Calvin L. Stevens

Canada

Canada is a country in North America.

See Ketamine and Canada

Canada Gazette

The Canada Gazette (Gazette du Canada) is the official government gazette of the Government of Canada.

See Ketamine and Canada Gazette

Cardiovascular disease

Cardiovascular disease (CVD) is any disease involving the heart or blood vessels.

See Ketamine and Cardiovascular disease

Case report

In medicine, a case report is a detailed report of the symptoms, signs, diagnosis, treatment, and follow-up of an individual patient.

See Ketamine and Case report

Cell signaling

In biology, cell signaling (cell signalling in British English) is the process by which a cell interacts with itself, other cells, and the environment.

See Ketamine and Cell signaling

Centre for Addiction and Mental Health

The Centre for Addiction and Mental Health (CAMH, pronounced, Centre de toxicomanie et de santé mentale) is a psychiatric teaching hospital located in Toronto and ten community locations throughout the province of Ontario, Canada.

See Ketamine and Centre for Addiction and Mental Health

Cerebrospinal fluid

Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates.

See Ketamine and Cerebrospinal fluid

Chirality (chemistry)

In chemistry, a molecule or ion is called chiral if it cannot be superposed on its mirror image by any combination of rotations, translations, and some conformational changes.

See Ketamine and Chirality (chemistry)

Chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by long-term respiratory symptoms and airflow limitation.

See Ketamine and Chronic obstructive pulmonary disease

Chronic pain

Chronic pain or chronic pain syndrome is a type of pain that is also known by other titles such as gradual burning pain, electrical pain, throbbing pain, and nauseating pain.

See Ketamine and Chronic pain

Circulatory system

The circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate.

See Ketamine and Circulatory system

Cirrhosis

Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is a condition of the liver in which the normal functioning tissue, or parenchyma, is replaced with scar tissue (fibrosis) and regenerative nodules as a result of chronic liver disease.

See Ketamine and Cirrhosis

Clonidine

Clonidine, sold under the brand name Catapres among others, is an α2A-adrenergic agonist medication used to treat high blood pressure, ADHD, drug withdrawal (alcohol, opioids, or nicotine), menopausal flushing, diarrhea, spasticity, and certain pain conditions.

See Ketamine and Clonidine

Clonus

Clonus is a set of involuntary and rhythmic muscular contractions and relaxations.

See Ketamine and Clonus

Cochrane (organisation)

Cochrane is a British international charitable organisation formed to synthesize medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers.

See Ketamine and Cochrane (organisation)

Complex regional pain syndrome

Complex regional pain syndrome (CRPS Type 1 and Type 2) is a severe form of chronic pain, in which pain from a physical trauma outlasts the expected recovery time.

See Ketamine and Complex regional pain syndrome

Compounding

In the field of pharmacy, compounding (performed in compounding pharmacies) is preparation of custom medications to fit unique needs of patients that cannot be met with mass-produced products.

See Ketamine and Compounding

Contraindication

In medicine, a contraindication is a condition (a situation or factor) that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient.

See Ketamine and Contraindication

Controlled substance

A controlled substance is generally a drug or chemical whose manufacture, possession and use is regulated by a government, such as illicitly used drugs or prescription medications that are designated by law.

See Ketamine and Controlled substance

Controlled Substances Act

The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated.

See Ketamine and Controlled Substances Act

Cyanotic heart defect

A cyanotic heart defect is any congenital heart defect (CHD) that occurs due to deoxygenated blood bypassing the lungs and entering the systemic circulation, or a mixture of oxygenated and unoxygenated blood entering the systemic circulation.

See Ketamine and Cyanotic heart defect

CYP2A6

Cytochrome P450 2A6 (abbreviated CYP2A6) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body.

See Ketamine and CYP2A6

CYP2B6

Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene.

See Ketamine and CYP2B6

CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine, which in humans is encoded by CYP3A4 gene.

See Ketamine and CYP3A4

D. M. Turner

D.M. Turner (born Joseph Vivian; 5 October 1962 – 31 December 1996) was an author, psychedelic researcher and psychonaut who wrote two books on psychoactive drugs and entheogens.

See Ketamine and D. M. Turner

Date rape

Date rape is a form of acquaintance rape and dating violence.

See Ketamine and Date rape

David Woodard

David James Woodard (born April 6, 1964) is an American conductor and writer.

See Ketamine and David Woodard

Decalin

Decalin (decahydronaphthalene, also known as bicyclodecane and sometimes decaline), a bicyclic organic compound, is an industrial solvent.

See Ketamine and Decalin

Dehydronorketamine

Dehydronorketamine (DHNK), or 5,6-dehydronorketamine, is a minor metabolite of ketamine which is formed by dehydrogenation of its metabolite norketamine. Ketamine and Dehydronorketamine are Chloroarenes and nicotinic antagonists.

See Ketamine and Dehydronorketamine

Depersonalization

Depersonalization is a dissociative phenomenon characterized by a subjective feeling of detachment from oneself, manifesting as a sense of disconnection from one's thoughts, emotions, sensations, or actions, and often accompanied by a feeling of observing oneself from an external perspective.

See Ketamine and Depersonalization

Depression (mood)

Depression is a mental state of low mood and aversion to activity.

See Ketamine and Depression (mood)

Derealization

Derealization is an alteration in the perception of the external world, causing those with the condition to perceive it as unreal, distant, distorted or in other words falsified.

See Ketamine and Derealization

Detomidine

Detomidine is an imidazole derivative and α2-adrenergic agonist, used as a large animal sedative, primarily used in horses. Ketamine and Detomidine are Equine medications and sedatives.

See Ketamine and Detomidine

Dissociation (psychology)

Dissociation is a concept that has been developed over time and which concerns a wide array of experiences, ranging from a mild emotional detachment from the immediate surroundings, to a more severe disconnection from physical and emotional experiences.

See Ketamine and Dissociation (psychology)

Dissociative

Dissociatives, colloquially dissos, are a subclass of hallucinogens that distort perception of sight and sound and produce feelings of detachment – dissociation – from the environment and/or self. Ketamine and Dissociative are dissociative drugs.

See Ketamine and Dissociative

Distribution (pharmacology)

Distribution in pharmacology is a branch of pharmacokinetics which describes the reversible transfer of a drug from one location to another within the body.

See Ketamine and Distribution (pharmacology)

Dopamine receptor D2

Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.

See Ketamine and Dopamine receptor D2

Dopaminergic pathways

Dopaminergic pathways (dopamine pathways, dopaminergic projections) in the human brain are involved in both physiological and behavioral processes including movement, cognition, executive functions, reward, motivation, and neuroendocrine control.

See Ketamine and Dopaminergic pathways

Downregulation and upregulation

In biochemistry, in the biological context of organisms' regulation of gene expression and production of gene products, downregulation is the process by which a cell decreases the production and quantities of its cellular components, such as RNA and proteins, in response to an external stimulus.

See Ketamine and Downregulation and upregulation

Drug tolerance

Drug tolerance or drug insensitivity is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use.

See Ketamine and Drug tolerance

Drug withdrawal

Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome, is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs.

See Ketamine and Drug withdrawal

Drugs and Cosmetics Rules, 1945

The Drugs and Cosmetics Rules, 1945 are the rules which the government of India established for the implementation of the Drugs and Cosmetics Act, 1940.

See Ketamine and Drugs and Cosmetics Rules, 1945

Drugs.com

Drugs.com is an online pharmaceutical encyclopedia that provides drug information for consumers and healthcare professionals, primarily in the United States.

See Ketamine and Drugs.com

Dysphoria

Dysphoria is a profound state of unease or dissatisfaction.

See Ketamine and Dysphoria

Dysuria

Dysuria refers to painful or uncomfortable urination.

See Ketamine and Dysuria

EEF2

Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene.

See Ketamine and EEF2

Emergence delirium

Emergence delirium is a condition in which emergence from general anesthesia is accompanied by psychomotor agitation.

See Ketamine and Emergence delirium

Emergency medicine

Emergency medicine is the medical speciality concerned with the care of illnesses or injuries requiring immediate medical attention.

See Ketamine and Emergency medicine

Enantiomer

In chemistry, an enantiomer (/ɪˈnænti.əmər, ɛ-, -oʊ-/ ''ih-NAN-tee-ə-mər''; from Ancient Greek ἐναντίος (enantíos) 'opposite', and μέρος (méros) 'part') – also called optical isomer, antipode, or optical antipode – is one of two stereoisomers that are nonsuperposable onto their own mirror image.

See Ketamine and Enantiomer

Enantiopure drug

An enantiopure drug is a pharmaceutical that is available in one specific enantiomeric form.

See Ketamine and Enantiopure drug

Entheogen

Entheogens are psychoactive substances, including psychedelic drugs, such as magic mushrooms and magic plants used in sacred contexts in religion for inducing spiritual development throughout history.

See Ketamine and Entheogen

Eosinophilic cystitis

Eosinophilic cystitis is a rare type of interstitial cystitis first reported in 1960 by Edwin Brown.

See Ketamine and Eosinophilic cystitis

Epidural administration

Epidural administration (from Ancient Greek ἐπί, "upon" + dura mater) is a method of medication administration in which a medicine is injected into the epidural space around the spinal cord.

See Ketamine and Epidural administration

Epithelium

Epithelium or epithelial tissue is a thin, continuous, protective layer of compactly packed cells with little extracellular matrix.

See Ketamine and Epithelium

Esketamine

Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, is the S(+) enantiomer of ketamine. Ketamine and Esketamine are antidepressants, Arylcyclohexylamines, Chloroarenes, dissociative drugs, general anesthetics, ketones, NMDA receptor antagonists, nicotinic antagonists and sedatives.

See Ketamine and Esketamine

European Medicines Agency

The European Medicines Agency (EMA) is an agency of the European Union (EU) in charge of the evaluation and supervision of pharmaceutical products.

See Ketamine and European Medicines Agency

Experimentation on prisoners

Throughout history, prisoners have been frequent participants in scientific, medical and social human subject research.

See Ketamine and Experimentation on prisoners

Feces

Feces (or faeces;: faex) are the solid or semi-solid remains of food that was not digested in the small intestine, and has been broken down by bacteria in the large intestine.

See Ketamine and Feces

Federal Register

The Federal Register (FR or sometimes Fed. Reg.) is the official journal of the federal government of the United States that contains government agency rules, proposed rules, and public notices.

See Ketamine and Federal Register

Feral House

Feral House is an American book publisher founded in 1989 by Adam Parfrey and based in Port Townsend, Washington.

See Ketamine and Feral House

First pass effect

The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.

See Ketamine and First pass effect

Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

See Ketamine and Food and Drug Administration

Free base

Free base (freebase, free-base) is a descriptor for the neutral form of an amine commonly used in reference to illicit drugs.

See Ketamine and Free base

Frequent urination

Frequent urination, or urinary frequency (sometimes called pollakiuria), is the need to urinate more often than usual.

See Ketamine and Frequent urination

Gastrointestinal disease

Gastrointestinal diseases (abbrev. GI diseases or GI illnesses) refer to diseases involving the gastrointestinal tract, namely the esophagus, stomach, small intestine, large intestine and rectum; and the accessory organs of digestion, the liver, gallbladder, and pancreas.

See Ketamine and Gastrointestinal disease

Gastrointestinal tract

The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines.

See Ketamine and Gastrointestinal tract

General anaesthesia

General anaesthesia (UK) or general anesthesia (US) is a method of medically inducing loss of consciousness that renders a patient unarousable even with painful stimuli.

See Ketamine and General anaesthesia

General anaesthetic

General anaesthetics (or anesthetics) are often defined as compounds that induce a loss of consciousness in humans or loss of righting reflex in animals. Ketamine and General anaesthetic are drugs with unknown mechanisms of action.

See Ketamine and General anaesthetic

Glutamate (neurotransmitter)

In neuroscience, glutamate is the anion of glutamic acid in its role as a neurotransmitter (a chemical that nerve cells use to send signals to other cells).

See Ketamine and Glutamate (neurotransmitter)

Government of Canada

The Government of Canada (Gouvernement du Canada) is the body responsible for the federal administration of Canada.

See Ketamine and Government of Canada

Government of India

The Government of India (IAST: Bhārat Sarkār, legally the Union Government or Union of India and colloquially known as the Central Government) is the central executive authority of the Republic of India, a federal republic located in South Asia, consisting of 28 states and eight union territories.

See Ketamine and Government of India

Grignard reagent

Grignard reagents or Grignard compounds are chemical compounds with the general formula, where X is a halogen and R is an organic group, normally an alkyl or aryl.

See Ketamine and Grignard reagent

GSK-3

Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino acid residues.

See Ketamine and GSK-3

Guaifenesin

Guaifenesin, also known as glyceryl guaiacolate, is an expectorant medication taken by mouth and marketed as an aid to eliminate sputum from the respiratory tract. Ketamine and Guaifenesin are drugs with unknown mechanisms of action.

See Ketamine and Guaifenesin

Habenula

The habenula (diminutive of Latin meaning rein) is a small bilateral neuronal structure in the brain of vertebrates, that has also been called a microstructure since it is no bigger than a pea.

See Ketamine and Habenula

Hallucinogen

Hallucinogens are a large and diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes.

See Ketamine and Hallucinogen

Hematuria

Hematuria or haematuria is defined as the presence of blood or red blood cells in the urine.

See Ketamine and Hematuria

Hyaluronic acid

Hyaluronic acid (abbreviated HA; conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues.

See Ketamine and Hyaluronic acid

Hydrochloride

In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine).

See Ketamine and Hydrochloride

Hydronephrosis

Hydronephrosis describes hydrostatic dilation of the renal pelvis and calyces as a result of obstruction to urine flow downstream.

See Ketamine and Hydronephrosis

Hydroxynorketamine

Hydroxynorketamine (HNK), or 6-hydroxynorketamine, is a minor metabolite of the anesthetic, dissociative, and antidepressant drug ketamine. Ketamine and Hydroxynorketamine are antidepressants, Arylcyclohexylamines, Chloroarenes, drugs with unknown mechanisms of action and nicotinic antagonists.

See Ketamine and Hydroxynorketamine

Hypertension

Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

See Ketamine and Hypertension

Hypertensive crisis

Severely elevated blood pressure (equal to or greater than 180 mmHg systolic or 120 mmHg diastolic) is referred to as a hypertensive crisis (sometimes termed malignant or accelerated hypertension), due to the high risk of complications.

See Ketamine and Hypertensive crisis

Hypertonia

Hypertonia is a term sometimes used synonymously with spasticity and ''rigidity'' in the literature surrounding damage to the central nervous system, namely upper motor neuron lesions.

See Ketamine and Hypertonia

Hypotension

Hypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure.

See Ketamine and Hypotension

IC50

Half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.

See Ketamine and IC50

Inner Traditions – Bear & Company

Inner Traditions – Bear & Company, also known as Inner Traditions, is a book publisher founded by Ehud Sperling in 1975 and based in Rochester, Vermont in the United States.

See Ketamine and Inner Traditions – Bear & Company

Insufflation (medicine)

Insufflation (lit) is the act of blowing something (such as a gas, powder, or vapor) into a body cavity.

See Ketamine and Insufflation (medicine)

Interstitial cystitis

Interstitial cystitis (IC), a type of bladder pain syndrome (BPS), is chronic pain in the bladder and pelvic floor of unknown cause.

See Ketamine and Interstitial cystitis

Intramuscular injection

Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle.

See Ketamine and Intramuscular injection

Intraocular pressure

Intraocular pressure (IOP) is the fluid pressure inside the eye.

See Ketamine and Intraocular pressure

Intravenous therapy

Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.

See Ketamine and Intravenous therapy

Intravesical drug delivery

Intravesical drug delivery is the delivery of medications directly into the bladder by urinary catheter.

See Ketamine and Intravesical drug delivery

Ionotropic glutamate receptor

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.

See Ketamine and Ionotropic glutamate receptor

Isozyme

In biochemistry, isozymes (also known as isoenzymes or more generally as multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction.

See Ketamine and Isozyme

Ivermectin

Ivermectin is an antiparasitic drug. Ketamine and Ivermectin are world Health Organization essential medicines.

See Ketamine and Ivermectin

Α-Ketol rearrangement

The α-ketol rearrangement is the acid-, base-, or heat-induced 1,2-migration of an alkyl or aryl group in an α-hydroxy ketone or aldehyde to give an isomeric product.

See Ketamine and Α-Ketol rearrangement

John C. Lilly

John Cunningham Lilly (January 6, 1915 – September 30, 2001) at NNDB.

See Ketamine and John C. Lilly

K-hole

K-hole is the feeling of getting a high enough dose of ketamine to experience a state of dissociation.

See Ketamine and K-hole

Ketofol

Ketofol is a mixture of ketamine and propofol. Ketamine and Ketofol are general anesthetics and NMDA receptor antagonists.

See Ketamine and Ketofol

Kidney failure

Kidney failure, also known as end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. Kidney failure is classified as either acute kidney failure, which develops rapidly and may resolve; and chronic kidney failure, which develops slowly and can often be irreversible.

See Ketamine and Kidney failure

Kinase

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.

See Ketamine and Kinase

Lamotrigine

Lamotrigine, sold under the brand name Lamictal among others, is a medication used to treat epilepsy and stabilize mood in bipolar disorder. Ketamine and Lamotrigine are Chloroarenes, drugs with unknown mechanisms of action and world Health Organization essential medicines.

See Ketamine and Lamotrigine

Lanicemine

Lanicemine (AZD6765) is a low-trapping NMDA receptor antagonist that was under development by AstraZeneca for the management of severe and treatment-resistant depression. Ketamine and Lanicemine are NMDA receptor antagonists.

See Ketamine and Lanicemine

Laryngospasm

Laryngospasm is an uncontrolled or involuntary muscular contraction (spasm) of the vocal folds.

See Ketamine and Laryngospasm

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

See Ketamine and Ligand (biochemistry)

Limbic system

The limbic system, also known as the paleomammalian cortex, is a set of brain structures located on both sides of the thalamus, immediately beneath the medial temporal lobe of the cerebrum primarily in the forebrain.

See Ketamine and Limbic system

List of hepato-biliary diseases

Hepato-biliary diseases include liver diseases and biliary diseases.

See Ketamine and List of hepato-biliary diseases

Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

See Ketamine and Liver

Los Angeles

Los Angeles, often referred to by its initials L.A., is the most populous city in the U.S. state of California.

See Ketamine and Los Angeles

Major depressive disorder

Major depressive disorder (MDD), also known as clinical depression, is a mental disorder characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities.

See Ketamine and Major depressive disorder

Marcia Moore

Marcia Moore (May 22, 1928 – January 14, 1979) was an American writer, astrologer and yoga teacher brought to national attention in 1965 through Jess Stearn's book Yoga, Youth, and Reincarnation.

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Matthew Perry

Matthew Langford Perry (August 19, 1969 – October 28, 2023) was an American and Canadian actor.

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Medical guideline

A medical guideline (also called a clinical guideline, standard treatment guideline, or clinical practice guideline) is a document with the aim of guiding decisions and criteria regarding diagnosis, management, and treatment in specific areas of healthcare.

See Ketamine and Medical guideline

Medical imaging

Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology).

See Ketamine and Medical imaging

Medicine

Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health.

See Ketamine and Medicine

Memantine

Memantine, sold under the brand name Axura among others, is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. It is taken by mouth. Common side effects include headache, constipation, sleepiness, and dizziness. Severe side effects may include blood clots, psychosis, and heart failure. Ketamine and Memantine are dissociative drugs, NMDA receptor antagonists and sigma agonists.

See Ketamine and Memantine

Mesolimbic pathway

The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain.

See Ketamine and Mesolimbic pathway

Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms.

See Ketamine and Metabolism

Metabolite

In biochemistry, a metabolite is an intermediate or end product of metabolism.

See Ketamine and Metabolite

Methylamine

Methylamine is an organic compound with a formula of.

See Ketamine and Methylamine

Midazolam

Midazolam, sold under the brand name Versed among others, is a benzodiazepine medication used for anesthesia, premedication before surgical anesthesia, and procedural sedation, and to treat severe agitation. Ketamine and Midazolam are chemical substances for emergency medicine and world Health Organization essential medicines.

See Ketamine and Midazolam

Misuse of Drugs Act 1971

The Misuse of Drugs Act 1971 (c. 38) is an act of the Parliament of the United Kingdom.

See Ketamine and Misuse of Drugs Act 1971

Molar concentration

Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular, of a solute in a solution, in terms of amount of substance per unit volume of solution.

See Ketamine and Molar concentration

Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B). Ketamine and monoamine oxidase inhibitor are antidepressants.

See Ketamine and Monoamine oxidase inhibitor

Monoamine reuptake inhibitor

A monoamine reuptake inhibitor (MRI) is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin, norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).

See Ketamine and Monoamine reuptake inhibitor

Monoamine transporter

Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters.

See Ketamine and Monoamine transporter

Morphine

Morphine, formerly also called morphia, is an opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (Papaver somniferum). Ketamine and Morphine are chemical substances for emergency medicine, Euphoriants and world Health Organization essential medicines.

See Ketamine and Morphine

MTOR

The mammalian target of rapamycin (mTOR), also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by the MTOR gene.

See Ketamine and MTOR

Muscarinic acetylcholine receptor M1

The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by the CHRM1 gene.

See Ketamine and Muscarinic acetylcholine receptor M1

N-Methyl-D-aspartic acid

N-methyl--aspartic acid or N-methyl--aspartate (NMDA) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.

See Ketamine and N-Methyl-D-aspartic acid

Naltrexone

Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol use or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. It has also been found effective in the treatment of other addictions and may be used for them off-label. Ketamine and Naltrexone are ketones and world Health Organization essential medicines.

See Ketamine and Naltrexone

Nasal administration

Nasal administration, popularly known as snorting, is a route of administration in which drugs are insufflated through the nose.

See Ketamine and Nasal administration

Near-death experience

A near-death experience (NDE) is a profound personal experience associated with death or impending death, which researchers describe as having similar characteristics.

See Ketamine and Near-death experience

Neuromuscular disease

A neuromuscular disease is any disease affecting the peripheral nervous system (PNS), the neuromuscular junctions, or skeletal muscles, all of which are components of the motor unit.

See Ketamine and Neuromuscular disease

Neuromuscular-blocking drug

Neuromuscular-blocking drugs, or Neuromuscular blocking agents (NMBAs), block transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles.

See Ketamine and Neuromuscular-blocking drug

Neuroplasticity

Neuroplasticity, also known as neural plasticity or brain plasticity, is the ability of neural networks in the brain to change through growth and reorganization.

See Ketamine and Neuroplasticity

Neurotransmission

Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and react with the receptors on the dendrites of another neuron (the postsynaptic neuron) a short distance away.

See Ketamine and Neurotransmission

Nicotinic acetylcholine receptor

Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine.

See Ketamine and Nicotinic acetylcholine receptor

Nimodipine

Nimodipine, sold under the brand name Nimotop among others, is a calcium channel blocker used in preventing vasospasm secondary to subarachnoid hemorrhage (a form of cerebral hemorrhage).

See Ketamine and Nimodipine

Nitrous oxide

Nitrous oxide (dinitrogen oxide or dinitrogen monoxide), commonly known as laughing gas, nitrous, nitro, or nos, is a chemical compound, an oxide of nitrogen with the formula. Ketamine and nitrous oxide are dissociative drugs, Euphoriants, general anesthetics, NMDA receptor antagonists, nicotinic antagonists and world Health Organization essential medicines.

See Ketamine and Nitrous oxide

NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons. Ketamine and NMDA receptor are NMDA receptor antagonists.

See Ketamine and NMDA receptor

NMDA receptor antagonist

NMDA receptor antagonists are a class of drugs that work to antagonize, or inhibit the action of, the ''N''-Methyl-D-aspartate receptor (NMDAR). Ketamine and NMDA receptor antagonist are general anesthetics and NMDA receptor antagonists.

See Ketamine and NMDA receptor antagonist

Nociplastic pain

Nociplastic pain, also known as central sensitisation, is the consensus semantic term used by medical researchers to describe a third category of pain that is mechanistically distinct from nociceptive pain, due to inflammation and tissue damage, and neuropathic pain, due to nerve damage.

See Ketamine and Nociplastic pain

Nonsteroidal anti-inflammatory drug

Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots.

See Ketamine and Nonsteroidal anti-inflammatory drug

Norketamine

Norketamine, or N-desmethylketamine, is the major active metabolite of ketamine, which is formed mainly by CYP3A4. Ketamine and Norketamine are antidepressants, Arylcyclohexylamines, Chloroarenes, dissociative drugs, general anesthetics, ketones, NMDA receptor antagonists, nicotinic antagonists and sedatives.

See Ketamine and Norketamine

Open Government Licence

The Open Government Licence (OGL) is a copyright licence for Crown copyright works published by the UK government.

See Ketamine and Open Government Licence

Opioid-induced hyperalgesia

Opioid-induced hyperalgesia (OIH) or opioid-induced abnormal pain sensitivity, also called paradoxical hyperalgesia, is an uncommon condition of generalized pain caused by the long-term use of high dosages of opioids such as morphine, oxycodone, and methadone.

See Ketamine and Opioid-induced hyperalgesia

Optical rotation

Optical rotation, also known as polarization rotation or circular birefringence, is the rotation of the orientation of the plane of polarization about the optical axis of linearly polarized light as it travels through certain materials.

See Ketamine and Optical rotation

Oral administration

| name.

See Ketamine and Oral administration

Pain management

Pain management is an aspect of medicine and health care involving relief of pain (pain relief, analgesia, pain control) in various dimensions, from acute and simple to chronic and challenging.

See Ketamine and Pain management

Pain wind-up

Pain wind-up is the increase in pain intensity over time when a given stimulus is delivered repeatedly above a critical rate.

See Ketamine and Pain wind-up

Parke-Davis

Parke-Davis is a subsidiary of the pharmaceutical company Pfizer.

See Ketamine and Parke-Davis

Pentosan polysulfate

Pentosan polysulfate, sold under the brand name Elmiron among others, is a medication used for the treatment of interstitial cystitis.

See Ketamine and Pentosan polysulfate

Pharmacodynamics

Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).

See Ketamine and Pharmacodynamics

Phencyclidine

Phencyclidine or phenylcyclohexyl piperidine (PCP), also known in its use as a street drug as angel dust among other names, is a dissociative anesthetic mainly used recreationally for its significant mind-altering effects. Ketamine and Phencyclidine are Arylcyclohexylamines, d2-receptor agonists, dissociative drugs, Euphoriants, general anesthetics, NMDA receptor antagonists, nicotinic antagonists and sigma agonists.

See Ketamine and Phencyclidine

Philip Seeman

Philip Seeman, (8 February 1934 – 9 January 2021) was a Canadian schizophrenia researcher and neuropharmacologist, known for his research on dopamine receptors.

See Ketamine and Philip Seeman

Phosphorylation

In biochemistry, phosphorylation is the attachment of a phosphate group to a molecule or an ion.

See Ketamine and Phosphorylation

Plasma protein binding

Plasma protein binding refers to the degree to which medications attach to blood proteins within the blood plasma.

See Ketamine and Plasma protein binding

Postanesthetic shivering

Postanesthetic shivering (PAS) is shivering after anesthesia.

See Ketamine and Postanesthetic shivering

Posterior grey column

The posterior grey column (posterior cornu, dorsal horn, spinal dorsal horn, posterior horn, sensory horn) is one of the three grey columns of the spinal cord.

See Ketamine and Posterior grey column

Potency (pharmacology)

In pharmacology, potency or biological potency is a measure of a drug's biological activity expressed in terms of the dose required to produce a pharmacological effect of given intensity.

See Ketamine and Potency (pharmacology)

Potentiator

In clinical terms, a potentiator is a reagent that enhances sensitization of an antigen.

See Ketamine and Potentiator

Preclinical development

In drug development, preclinical development (also termed preclinical studies or nonclinical studies) is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals.

See Ketamine and Preclinical development

Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

See Ketamine and Pregnancy

Prolactin

Prolactin (PRL), also known as lactotropin and mammotropin, is a protein best known for its role in enabling mammals to produce milk.

See Ketamine and Prolactin

Propofol

Propofol is the active component of an intravenous anesthetic formulation used for induction and maintenance of general anesthesia. Ketamine and Propofol are chemical substances for emergency medicine, general anesthetics and world Health Organization essential medicines.

See Ketamine and Propofol

Psychonautics

Psychonautics (from the Ancient Greek ψυχή psychē 'soul, spirit, mind' and ναύτης naútēs 'sailor, navigator') refers both to a methodology for describing and explaining the subjective effects of altered states of consciousness, including those induced by meditation or mind-altering substances, and to a research cabal in which the researcher voluntarily immerses themselves into an altered mental state in order to explore the accompanying experiences.

See Ketamine and Psychonautics

Psychoplastogen

Psychoplastogens are a group of small molecule drugs that produce rapid and sustained effects on neuronal structure and function, intended to manifest therapeutic benefit after a single administration.

See Ketamine and Psychoplastogen

Psychosis

Psychosis is a condition of the mind or psyche that results in difficulties determining what is real and what is not real.

See Ketamine and Psychosis

Psychotomimetism

A drug with psychotomimetic (also known as psychotogenic) actions mimics the symptoms of psychosis, including delusions and/or delirium, as opposed to only hallucinations.

See Ketamine and Psychotomimetism

Rabbit

Rabbits are small mammals in the family Leporidae (which also includes the hares), which is in the order Lagomorpha (which also includes pikas).

See Ketamine and Rabbit

Racemic mixture

In chemistry, a racemic mixture or racemate is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule or salt.

See Ketamine and Racemic mixture

Raclopride

Raclopride is a typical antipsychotic. Ketamine and Raclopride are Chloroarenes.

See Ketamine and Raclopride

Randomized controlled trial

A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control.

See Ketamine and Randomized controlled trial

Rapastinel

Rapastinel (former developmental code name GLYX-13) is a novel antidepressant that was under development by Allergan (previously Naurex) as an adjunctive therapy for the treatment of treatment-resistant depression. Ketamine and Rapastinel are antidepressants.

See Ketamine and Rapastinel

Rat

Rats are various medium-sized, long-tailed rodents.

See Ketamine and Rat

Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

See Ketamine and Receptor antagonist

Recreational drug use

Recreational drug use is the use of one or more psychoactive drugs to induce an altered state of consciousness, either for pleasure or for some other casual purpose or pastime.

See Ketamine and Recreational drug use

Rectal administration

Rectal administration (colloquially known as boofing or plugging) uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels,The rectum has numerous blood vessels available to absorb drugs: upwards 2/3rds of the dose bypasses first-pass metabolism through systemic distribution and the rest is taken through the liver and metabolized via the hepatic portal system.

See Ketamine and Rectal administration

Respiratory system

The respiratory system (also respiratory apparatus, ventilatory system) is a biological system consisting of specific organs and structures used for gas exchange in animals and plants.

See Ketamine and Respiratory system

Rislenemdaz

Rislenemdaz (developmental code names CERC-301, MK-0657) is an orally active, selective NMDA receptor subunit 2B (NR2B) antagonist which is under development by Cerecor in the United States as an adjunctive therapy for treatment-resistant depression (TRD). Ketamine and Rislenemdaz are NMDA receptor antagonists.

See Ketamine and Rislenemdaz

Rodent

Rodents (from Latin rodere, 'to gnaw') are mammals of the order Rodentia, which are characterized by a single pair of continuously growing incisors in each of the upper and lower jaws.

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Rodent cocktail

Rodent cocktail is an anesthetic mixture used for rodents in research. Ketamine and rodent cocktail are general anesthetics.

See Ketamine and Rodent cocktail

Ronin Publishing

Ronin Publishing, Inc. is a small press in Berkeley, California, founded in 1983 and incorporated in 1985, which publishes books as tools for personal development, visionary alternatives, and expanded consciousness.

See Ketamine and Ronin Publishing

Salt (chemistry)

In chemistry, a salt or ionic compound is a chemical compound consisting of an assembly of positively charged ions (cations) and negatively charged ions (anions), which results in a compound with no net electric charge (electrically neutral).

See Ketamine and Salt (chemistry)

Schedule X

Schedule X is a class of prescription drugs in India appearing as an appendix to the Drugs and Cosmetics Rules introduced in 1945.

See Ketamine and Schedule X

Secretion

Secretion is the movement of material from one point to another, such as a secreted chemical substance from a cell or gland.

See Ketamine and Secretion

Sedation

Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.

See Ketamine and Sedation

Sedative

A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. Ketamine and sedative are sedatives.

See Ketamine and Sedative

Sensitization

Sensitization is a non-associative learning process in which repeated administration of a stimulus results in the progressive amplification of a response.

See Ketamine and Sensitization

Serotonin syndrome

Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs.

See Ketamine and Serotonin syndrome

Shock (circulatory)

Shock is the state of insufficient blood flow to the tissues of the body as a result of problems with the circulatory system.

See Ketamine and Shock (circulatory)

Sigma-2 receptor

The sigma-2 receptor (σ2R) is a sigma receptor subtype that has attracted attention due to its involvement in diseases such as neurological diseases, neurodegenerative, neuro-ophthalmic and cancer.

See Ketamine and Sigma-2 receptor

Sodium thiopental

Sodium thiopental, also known as Sodium Pentothal (a trademark of Abbott Laboratories), thiopental, thiopentone, or Trapanal (also a trademark), is a rapid-onset short-acting barbiturate general anesthetic. Ketamine and Sodium thiopental are drugs developed by Pfizer, general anesthetics, nicotinic antagonists, sedatives and world Health Organization essential medicines.

See Ketamine and Sodium thiopental

Spinal cord

The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals.

See Ketamine and Spinal cord

Standard for the Uniform Scheduling of Medicines and Poisons

The Standard for the Uniform Scheduling of Medicines and Poisons (SUSMP), also known as the Poisons Standard for short, is an Australian legislative instrument produced by the Therapeutic Goods Administration (TGA).

See Ketamine and Standard for the Uniform Scheduling of Medicines and Poisons

Status epilepticus

Status epilepticus (SE), or status seizure, is a medical condition consisting of a single seizure lasting more than 5 minutes, or 2 or more seizures within a 5-minute period without the person returning to normal between them.

See Ketamine and Status epilepticus

Stereoisomerism

In stereochemistry, stereoisomerism, or spatial isomerism, is a form of isomerism in which molecules have the same molecular formula and sequence of bonded atoms (constitution), but differ in the three-dimensional orientations of their atoms in space.

See Ketamine and Stereoisomerism

Striatum

The striatum (striata) or corpus striatum is a cluster of interconnected nuclei that make up the largest structure of the subcortical basal ganglia.

See Ketamine and Striatum

Sublingual administration

Sublingual (abbreviated SL), from the Latin for "under the tongue", refers to the pharmacological route of administration by which substances diffuse into the blood through tissues under the tongue.

See Ketamine and Sublingual administration

Substance abuse

Substance abuse, also known as drug abuse, is the use of a drug in amounts or by methods that are harmful to the individual or others.

See Ketamine and Substance abuse

Substance use disorder

Substance use disorder (SUD) is the persistent use of drugs despite the substantial harm and adverse consequences to one's own self and others, as a result of their use.

See Ketamine and Substance use disorder

Suicidal ideation

Suicidal ideation, or suicidal thoughts, is the thought process of having ideas, or ruminations about the possibility of completing suicide.

See Ketamine and Suicidal ideation

Suicide

Suicide is the act of intentionally causing one's own death.

See Ketamine and Suicide

The Daily Telegraph

The Daily Telegraph, known online and elsewhere as The Telegraph, is a British daily broadsheet newspaper published in London by Telegraph Media Group and distributed in the United Kingdom and internationally.

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The Times of India

The Times of India, also known by its abbreviation TOI, is an Indian English-language daily newspaper and digital news media owned and managed by The Times Group.

See Ketamine and The Times of India

Tonic (physiology)

Tonic in physiology refers to a physiological response which is slow and may be graded.

See Ketamine and Tonic (physiology)

Tracheal intubation

Tracheal intubation, usually simply referred to as intubation, is the placement of a flexible plastic tube into the trachea (windpipe) to maintain an open airway or to serve as a conduit through which to administer certain drugs.

See Ketamine and Tracheal intubation

Tramadol

Tramadol, sold under the brand name Ultram among others, is an opioid pain medication and a serotonin–norepinephrine reuptake inhibitor (SNRI) used to treat moderately severe pain. Ketamine and Tramadol are analgesics, Euphoriants, muscarinic antagonists, NMDA receptor antagonists and nicotinic antagonists.

See Ketamine and Tramadol

Trance

Trance is a state of semi-consciousness in which a person is not self-aware and is either altogether unresponsive to external stimuli (but nevertheless capable of pursuing and realizing an aim) or is selectively responsive in following the directions of the person (if any) who has induced the trance.

See Ketamine and Trance

Transitional epithelium

Transitional epithelium is a type of stratified epithelium.

See Ketamine and Transitional epithelium

Tranylcypromine

Tranylcypromine, sold under the brand name Parnate among others, is a monoamine oxidase inhibitor (MAOI).

See Ketamine and Tranylcypromine

Treatment-resistant depression

Treatment-resistant depression (TRD) is a form of major depressive disorder (MDD) in which an affected person does not respond adequately to a course of appropriate antidepressant medication.

See Ketamine and Treatment-resistant depression

Tritium

Tritium or hydrogen-3 (symbol T or H) is a rare and radioactive isotope of hydrogen with half-life ~12.3 years.

See Ketamine and Tritium

Tropomyosin receptor kinase B

Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the NTRK2 gene.

See Ketamine and Tropomyosin receptor kinase B

TRPV1

The transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by the TRPV1 gene.

See Ketamine and TRPV1

United Kingdom

The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of the continental mainland.

See Ketamine and United Kingdom

University of Maryland, College Park

The University of Maryland, College Park (University of Maryland, UMD, or simply Maryland) is a public land-grant research university in College Park, Maryland.

See Ketamine and University of Maryland, College Park

Unstable angina

Unstable angina is a type of angina pectoris that is irregular or more easily provoked.

See Ketamine and Unstable angina

Upstream and downstream (transduction)

The upstream signaling pathway is triggered by the binding of a signaling molecule, a ligand, to a receiving molecule, a receptor.

See Ketamine and Upstream and downstream (transduction)

Urinary tract infection

A urinary tract infection (UTI) is an infection that affects a part of the urinary tract.

See Ketamine and Urinary tract infection

Urination

Urination is the release of urine from the bladder to the outside of the body.

See Ketamine and Urination

Urine

Urine is a liquid by-product of metabolism in humans and in many other animals.

See Ketamine and Urine

Veterinary anesthesia

Veterinary anesthesia is a specialization in the veterinary medicine field dedicated to the proper administration of anesthetic agents to non-human animals to control their consciousness during procedures. Ketamine and veterinary anesthesia are veterinary medicine.

See Ketamine and Veterinary anesthesia

Veterinary medicine

Veterinary medicine is the branch of medicine that deals with the prevention, management, diagnosis, and treatment of disease, disorder, and injury in non-human animals.

See Ketamine and Veterinary medicine

Vietnam War

The Vietnam War was a conflict in Vietnam, Laos, and Cambodia from 1 November 1955 to the fall of Saigon on 30 April 1975.

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Wayne State University

Wayne State University (WSU or simply Wayne) is a public research university in Detroit, Michigan.

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WHO Model List of Essential Medicines

The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. Ketamine and WHO Model List of Essential Medicines are world Health Organization essential medicines.

See Ketamine and WHO Model List of Essential Medicines

1-(2-Chloro-N-methylbenzimidoyl)cyclopentanol

1-(2-Chloro-N-methylbenzimidoyl)cyclopentanol, sometimes misleadingly referred to as hydroxylimine hydrochloride, is a chemical compound which is the final intermediate in the synthesis of ketamine, an anaesthetic drug which is also subject to recreational abuse.

See Ketamine and 1-(2-Chloro-N-methylbenzimidoyl)cyclopentanol

2-Chlorobenzonitrile

2-Chlorobenzonitrile is an organic compound with the formula ClC6H4CN.

See Ketamine and 2-Chlorobenzonitrile

4-Chlorokynurenine

L-4-Chlorokynurenine (4-Cl-KYN; developmental code name AV-101) is an orally active small molecule prodrug of 7-chlorokynurenic acid, a NMDA receptor antagonist. Ketamine and 4-Chlorokynurenine are antidepressants and NMDA receptor antagonists.

See Ketamine and 4-Chlorokynurenine

See also

Chemical substances for emergency medicine

D2-receptor agonists

Drug-facilitated sexual assault

Equine medications

Opioid modulators

References

[1] https://en.wikipedia.org/wiki/Ketamine

Also known as ATC code N01AX03, ATCvet code QN01AX03, CI 581, CI-581, CI581, CL 369, CL-369, CL369, CLSTA 20, CN 52372 2, CN 52372-2, CN-52372 2, CN-52372-2, CN52372 2, CN52372-2, Calypsol, Cat tranquilizer, Cat valium, K (drug), K-Hole, Ketaject, Ketalar, Ketalar base, Ketamin, Ketamina, Ketamine HCl, Ketamine Hydrochloride, Ketaminol, Ketaminum, Ketanest, Ketaset, Ketolar, Khole, Legal status of ketamine, Legality of ketamine, Recreational use of ketamine, Side effects of ketamine, Special K (drug), Tekam, Vetalar.

, Compounding, Contraindication, Controlled substance, Controlled Substances Act, Cyanotic heart defect, CYP2A6, CYP2B6, CYP3A4, D. M. Turner, Date rape, David Woodard, Decalin, Dehydronorketamine, Depersonalization, Depression (mood), Derealization, Detomidine, Dissociation (psychology), Dissociative, Distribution (pharmacology), Dopamine receptor D2, Dopaminergic pathways, Downregulation and upregulation, Drug tolerance, Drug withdrawal, Drugs and Cosmetics Rules, 1945, Drugs.com, Dysphoria, Dysuria, EEF2, Emergence delirium, Emergency medicine, Enantiomer, Enantiopure drug, Entheogen, Eosinophilic cystitis, Epidural administration, Epithelium, Esketamine, European Medicines Agency, Experimentation on prisoners, Feces, Federal Register, Feral House, First pass effect, Food and Drug Administration, Free base, Frequent urination, Gastrointestinal disease, Gastrointestinal tract, General anaesthesia, General anaesthetic, Glutamate (neurotransmitter), Government of Canada, Government of India, Grignard reagent, GSK-3, Guaifenesin, Habenula, Hallucinogen, Hematuria, Hyaluronic acid, Hydrochloride, Hydronephrosis, Hydroxynorketamine, Hypertension, Hypertensive crisis, Hypertonia, Hypotension, IC50, Inner Traditions – Bear & Company, Insufflation (medicine), Interstitial cystitis, Intramuscular injection, Intraocular pressure, Intravenous therapy, Intravesical drug delivery, Ionotropic glutamate receptor, Isozyme, Ivermectin, Α-Ketol rearrangement, John C. Lilly, K-hole, Ketofol, Kidney failure, Kinase, Lamotrigine, Lanicemine, Laryngospasm, Ligand (biochemistry), Limbic system, List of hepato-biliary diseases, Liver, Los Angeles, Major depressive disorder, Marcia Moore, Matthew Perry, Medical guideline, Medical imaging, Medicine, Memantine, Mesolimbic pathway, Metabolism, Metabolite, Methylamine, Midazolam, Misuse of Drugs Act 1971, Molar concentration, Monoamine oxidase inhibitor, Monoamine reuptake inhibitor, Monoamine transporter, Morphine, MTOR, Muscarinic acetylcholine receptor M1, N-Methyl-D-aspartic acid, Naltrexone, Nasal administration, Near-death experience, Neuromuscular disease, Neuromuscular-blocking drug, Neuroplasticity, Neurotransmission, Nicotinic acetylcholine receptor, Nimodipine, Nitrous oxide, NMDA receptor, NMDA receptor antagonist, Nociplastic pain, Nonsteroidal anti-inflammatory drug, Norketamine, Open Government Licence, Opioid-induced hyperalgesia, Optical rotation, Oral administration, Pain management, Pain wind-up, Parke-Davis, Pentosan polysulfate, Pharmacodynamics, Phencyclidine, Philip Seeman, Phosphorylation, Plasma protein binding, Postanesthetic shivering, Posterior grey column, Potency (pharmacology), Potentiator, Preclinical development, Pregnancy, Prolactin, Propofol, Psychonautics, Psychoplastogen, Psychosis, Psychotomimetism, Rabbit, Racemic mixture, Raclopride, Randomized controlled trial, Rapastinel, Rat, Receptor antagonist, Recreational drug use, Rectal administration, Respiratory system, Rislenemdaz, Rodent, Rodent cocktail, Ronin Publishing, Salt (chemistry), Schedule X, Secretion, Sedation, Sedative, Sensitization, Serotonin syndrome, Shock (circulatory), Sigma-2 receptor, Sodium thiopental, Spinal cord, Standard for the Uniform Scheduling of Medicines and Poisons, Status epilepticus, Stereoisomerism, Striatum, Sublingual administration, Substance abuse, Substance use disorder, Suicidal ideation, Suicide, The Daily Telegraph, The Times of India, Tonic (physiology), Tracheal intubation, Tramadol, Trance, Transitional epithelium, Tranylcypromine, Treatment-resistant depression, Tritium, Tropomyosin receptor kinase B, TRPV1, United Kingdom, University of Maryland, College Park, Unstable angina, Upstream and downstream (transduction), Urinary tract infection, Urination, Urine, Veterinary anesthesia, Veterinary medicine, Vietnam War, Wayne State University, WHO Model List of Essential Medicines, 1-(2-Chloro-N-methylbenzimidoyl)cyclopentanol, 2-Chlorobenzonitrile, 4-Chlorokynurenine.