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(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate

Index (E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate

(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP or HMB-PP) is an intermediate of the MEP pathway (non-mevalonate pathway) of isoprenoid biosynthesis. [1]

11 relations: Butyrophilin, subfamily 3, member A1, Dimethylallyl pyrophosphate, Gamma delta T cell, Isopentenyl pyrophosphate, Malaria, Mycobacterium tuberculosis, Non-mevalonate pathway, Non-peptidic antigen, 2-C-Methyl-D-erythritol-2,4-cyclopyrophosphate, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase.

Butyrophilin, subfamily 3, member A1

Butyrophilin subfamily 3 member A1 is a protein that in humans is encoded by the BTN3A1 gene.

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Dimethylallyl pyrophosphate

Dimethylallyl pyrophosphate (DMAPP; or alternatively, dimethylallyl diphosphate (DMADP); also isoprenyl pyrophosphate) is an isoprenoid precursor.

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Gamma delta T cell

Gamma delta T cells (γδ T cells) are T cells that have a distinctive T-cell receptor (TCR) on their surface.

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Isopentenyl pyrophosphate

Isopentenyl pyrophosphate (IPP, isopentenyl diphosphate, or IDP) is an isoprenoid precursor.

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Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.

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Mycobacterium tuberculosis

Mycobacterium tuberculosis is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis.

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Non-mevalonate pathway

The non-mevalonate pathway—also appearing as the mevalonate-independent pathway and the 2-C-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate (MEP/DOXP) pathway—is an alternative metabolic pathway for the biosynthesis of the isoprenoid precursors isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP).

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Non-peptidic antigen

Non-peptidic antigens are low-molecular-weight compounds that stimulate human Vγ9/Vδ2 T cells.

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2-C-Methyl-D-erythritol-2,4-cyclopyrophosphate (MEcPP) (also 2-C-Methyl-D-erythritol-2,4-cyclodiphosphate) is an intermediate in the MEP pathway (non-mevalonate) of isoprenoid precursor biosynthesis.

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4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase

In enzymology, a 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (HMB-PP synthase, IspG) is an enzyme that catalyzes the chemical reaction The substrate of this enzyme is 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEcPP) and the product is (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate (HMB-PP).

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4-Hydroxy-3-methylbut-2-enyl diphosphate reductase

4-Hydroxy-3-methylbut-2-enyl diphosphate reductase (isopentenyl-diphosphate:NADP+ oxidoreductase, LytB, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase, HMBPP reductase, IspH, LytB/IspH) is an enzyme in the non-mevalonate pathway.

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Redirects here:

(E)-4-hydroxy-3-methyl-but-2-enyl diphosphate, (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate, C5H12O8P2, GcpE, HMB-PP, Hmbpp.


[1] https://en.wikipedia.org/wiki/(E)-4-Hydroxy-3-methyl-but-2-enyl_pyrophosphate

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