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11-Deoxycortisol

Index 11-Deoxycortisol

11-Deoxycortisol, also known as cortodoxone (INN), cortexolone as well as 17α,21-dihydroxyprogesterone or 17α,21-dihydroxypregn-4-ene-3,20-dione, is an endogenous glucocorticoid steroid hormone, and a metabolic intermediate toward cortisol. [1]

Table of Contents

  1. 44 relations: Adrenal gland, Androstenedione, Biochemist, Biological activity, Chemical & Engineering News, Chicago Tribune, Clascoterone, Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency, Congenital adrenal hyperplasia due to 21-hydroxylase deficiency, Corticosterone, Cortisol, Cortisone, Cushing's syndrome, Electrolyte, Endogeny (biology), Enoxolone, Glucocorticoid, Hypertension, Hypotension, Industrial fermentation, International nonproprietary name, Journal of the American Chemical Society, Liquorice, Metabolic intermediate, Metamorphosis, Microbiologist, Mineralocorticoid, Mold, Mucorales, Percy Lavon Julian, Pregnenolone, Progesterone, Sea lamprey, Seawater, Steroid 11β-hydroxylase, Steroid hormone, Stigmasterol, Switzerland, Tadeusz Reichstein, Upjohn, Vascular resistance, 11-Deoxycorticosterone, 17α-Hydroxyprogesterone, 21-Hydroxylase.

  2. Metabolic intermediates
  3. Mineralocorticoids
  4. Steroid hormones

Adrenal gland

The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.

See 11-Deoxycortisol and Adrenal gland

Androstenedione

Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).

See 11-Deoxycortisol and Androstenedione

Biochemist

Biochemists are scientists who are trained in biochemistry.

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Biological activity

In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter.

See 11-Deoxycortisol and Biological activity

Chemical & Engineering News

Chemical & Engineering News (C&EN) is a weekly news magazine published by the American Chemical Society (ACS), providing professional and technical news and analysis in the fields of chemistry and chemical engineering.

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Chicago Tribune

The Chicago Tribune is an American daily newspaper based in Chicago, Illinois, owned by Tribune Publishing.

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Clascoterone

Clascoterone, sold under the brand name Winlevi, is an antiandrogen medication which is used topically in the treatment of acne. 11-Deoxycortisol and Clascoterone are Pregnanes.

See 11-Deoxycortisol and Clascoterone

Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency

Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency is a form of congenital adrenal hyperplasia (CAH) which produces a higher than normal amount of androgen, resulting from a defect in the gene encoding the enzyme steroid 11β-hydroxylase (11β-OH) which mediates the final step of cortisol synthesis in the adrenal.

See 11-Deoxycortisol and Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency (CAH) is a genetic disorder characterized by impaired production of cortisol in the adrenal glands.

See 11-Deoxycortisol and Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Corticosterone

Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroxyprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. 11-Deoxycortisol and Corticosterone are corticosteroids and Pregnanes.

See 11-Deoxycortisol and Corticosterone

Cortisol

Cortisol is a steroid hormone in the glucocorticoid class of hormones and a stress hormone. 11-Deoxycortisol and Cortisol are corticosteroids, glucocorticoids, Pregnanes, steroid hormones and steroids.

See 11-Deoxycortisol and Cortisol

Cortisone

Cortisone is a pregnene (21-carbon) steroid hormone. 11-Deoxycortisol and Cortisone are corticosteroids and Pregnanes.

See 11-Deoxycortisol and Cortisone

Cushing's syndrome

Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol.

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Electrolyte

An electrolyte is a medium containing ions that are electrically conductive through the movement of those ions, but not conducting electrons.

See 11-Deoxycortisol and Electrolyte

Endogeny (biology)

Endogenous substances and processes are those that originate from within a living system such as an organism, tissue, or cell.

See 11-Deoxycortisol and Endogeny (biology)

Enoxolone

Enoxolone (INN, BAN; also known as glycyrrhetinic acid or glycyrrhetic acid) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.

See 11-Deoxycortisol and Enoxolone

Glucocorticoid

Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. 11-Deoxycortisol and Glucocorticoid are corticosteroids and glucocorticoids.

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Hypertension

Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

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Hypotension

Hypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure.

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Industrial fermentation

Industrial fermentation is the intentional use of fermentation in manufacturing processes.

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International nonproprietary name

An international nonproprietary name (INN) is an official generic and nonproprietary name given to a pharmaceutical drug or an active ingredient.

See 11-Deoxycortisol and International nonproprietary name

Journal of the American Chemical Society

The Journal of the American Chemical Society (also known as JACS) is a weekly peer-reviewed scientific journal that was established in 1879 by the American Chemical Society.

See 11-Deoxycortisol and Journal of the American Chemical Society

Liquorice

Liquorice (British English) or licorice (American English) is the common name of Glycyrrhiza glabra, a flowering plant of the bean family Fabaceae, from the root of which a sweet, aromatic flavouring is extracted. The liquorice plant is an herbaceous perennial legume native to West Asia, North Africa, and Southern Europe.

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Metabolic intermediate

Metabolic intermediates are molecules that are the precursors or metabolites of biologically significant molecules.

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Metamorphosis

Metamorphosis is a biological process by which an animal physically develops including birth transformation or hatching, involving a conspicuous and relatively abrupt change in the animal's body structure through cell growth and differentiation.

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Microbiologist

A microbiologist (from Greek μῑκρος) is a scientist who studies microscopic life forms and processes.

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Mineralocorticoid

Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones. 11-Deoxycortisol and Mineralocorticoid are mineralocorticoids.

See 11-Deoxycortisol and Mineralocorticoid

Mold

A mold or mould is one of the structures that certain fungi can form.

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Mucorales

The Mucorales is the largest and best-studied order of zygomycete fungi.

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Percy Lavon Julian

Percy Lavon Julian (April 11, 1899 – April 19, 1975) was an American research chemist and a pioneer in the chemical synthesis of medicinal drugs from plants.

See 11-Deoxycortisol and Percy Lavon Julian

Pregnenolone

Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids. 11-Deoxycortisol and Pregnenolone are Pregnanes and steroid hormones.

See 11-Deoxycortisol and Pregnenolone

Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. 11-Deoxycortisol and Progesterone are glucocorticoids, Pregnanes and steroid hormones.

See 11-Deoxycortisol and Progesterone

Sea lamprey

The sea lamprey (Petromyzon marinus) is a parasitic lamprey native to the Northern Hemisphere.

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Seawater

Seawater, or sea water, is water from a sea or ocean.

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Steroid 11β-hydroxylase

Steroid 11β-hydroxylase, also known as steroid 11β-monooxygenase, is a steroid hydroxylase found in the zona glomerulosa and zona fasciculata of the adrenal cortex.

See 11-Deoxycortisol and Steroid 11β-hydroxylase

Steroid hormone

A steroid hormone is a steroid that acts as a hormone. 11-Deoxycortisol and steroid hormone are steroid hormones and steroids.

See 11-Deoxycortisol and Steroid hormone

Stigmasterol

Stigmasterol – a plant sterol (phytosterol) – is among the most abundant of plant sterols, having a major function to maintain the structure and physiology of cell membranes.

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Switzerland

Switzerland, officially the Swiss Confederation, is a landlocked country located in west-central Europe.

See 11-Deoxycortisol and Switzerland

Tadeusz Reichstein

Tadeusz Reichstein (20 July 1897 – 1 August 1996), also known as Tadeus Reichstein, was a Polish-Swiss chemist and the Nobel Prize in Physiology or Medicine laureate (1950), which was awarded for his work on the isolation of cortisone.

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Upjohn

The Upjohn Company was an American pharmaceutical manufacturing firm founded in 1886 in Hastings, Michigan, by Dr.

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Vascular resistance

Vascular resistance is the resistance that must be overcome for blood to flow through the circulatory system.

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11-Deoxycorticosterone

11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone, and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. 11-Deoxycortisol and 11-Deoxycorticosterone are mineralocorticoids, Pregnanes and steroid hormones.

See 11-Deoxycortisol and 11-Deoxycorticosterone

17α-Hydroxyprogesterone

17α-Hydroxyprogesterone (17α-OHP), also known as 17-OH progesterone (17-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone related to progesterone. 11-Deoxycortisol and 17α-Hydroxyprogesterone are glucocorticoids, metabolic intermediates and Pregnanes.

See 11-Deoxycortisol and 17α-Hydroxyprogesterone

21-Hydroxylase

Steroid 21-hydroxylase is a protein that in humans is encoded by the CYP21A2 gene.

See 11-Deoxycortisol and 21-Hydroxylase

See also

Metabolic intermediates

Mineralocorticoids

Steroid hormones

References

[1] https://en.wikipedia.org/wiki/11-Deoxycortisol

Also known as 11 deoxycortisol, 11-Deoxycortisone, 11-Desoxycortisol, 11-Desoxycortisone, 17,21-Dihydroxyprogesterone, 17α,21-Dihydroprogesterone, 17α,21-Dihydroxyprogesterone, Cortexolone, Cortodoxone, Reichsteins Substance S, Substance S.