2-Methoxyestradiol

2-Methoxyestradiol (2-ME2, 2-MeO-E2) is a natural metabolite of estradiol and 2-hydroxyestradiol (2-OHE2). ^[1]

39 relations: Agonist, Angiogenesis, Angiogenesis inhibitor, Apoptosis, Bioavailability, Blood vessel, Breast cancer, Cancer, Clinical trial, Drug development, Ester, Estradiol, Estrogen receptor, Ether, GPER, Immortalised cell line, Inflammation, Metabolism, Metabolite, Methyl group, Mitotic inhibitor, MP-2001, Natural product, Neoplasm, Oral administration, Ovarian cancer, Prostate cancer, Rheumatoid arthritis, Sex hormone-binding globulin, Structural analog, Sulfamic acid, Testosterone, Vasodilation, 2-Hydroxyestradiol, 2-Methoxyestradiol disulfamate, 2-Methoxyestriol, 2-Methoxyestrone, 4-Methoxyestradiol, 4-Methoxyestrone.
Angiogenesis inhibitors
GPER agonists
Hypolipidemic agents
Microtubule inhibitors
Mitotic inhibitors

Agonist

An agonist is a chemical that activates a receptor to produce a biological response.

Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, formed in the earlier stage of vasculogenesis.

See 2-Methoxyestradiol and Angiogenesis

Angiogenesis inhibitor

An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis). 2-Methoxyestradiol and angiogenesis inhibitor are angiogenesis inhibitors.

See 2-Methoxyestradiol and Angiogenesis inhibitor

Apoptosis

Apoptosis (from falling off) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast.

See 2-Methoxyestradiol and Apoptosis

Bioavailability

In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.

See 2-Methoxyestradiol and Bioavailability

Blood vessel

Blood vessels are the structures of the circulatory system that transport blood throughout the human body.

See 2-Methoxyestradiol and Blood vessel

Breast cancer

Breast cancer is a cancer that develops from breast tissue.

See 2-Methoxyestradiol and Breast cancer

Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

See 2-Methoxyestradiol and Cancer

Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison.

See 2-Methoxyestradiol and Clinical trial

Drug development

Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.

See 2-Methoxyestradiol and Drug development

Ester

In chemistry, an ester is a functional group derived from an acid (organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group of that acid is replaced by an organyl group.

See 2-Methoxyestradiol and Ester

Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. 2-Methoxyestradiol and Estradiol are Estranes, GPER agonists and Phenols.

See 2-Methoxyestradiol and Estradiol

Estrogen receptor

Estrogen receptors (ERs) are a group of proteins found inside cells.

See 2-Methoxyestradiol and Estrogen receptor

Ether

In organic chemistry, ethers are a class of compounds that contain an ether group—an oxygen atom bonded to two organyl groups (e.g., alkyl or aryl). 2-Methoxyestradiol and ether are ethers.

See 2-Methoxyestradiol and Ether

GPER

G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the GPER gene.

See 2-Methoxyestradiol and GPER

Immortalised cell line

An immortalised cell line is a population of cells from a multicellular organism that would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division.

See 2-Methoxyestradiol and Immortalised cell line

Inflammation

Inflammation (from inflammatio) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.

See 2-Methoxyestradiol and Inflammation

Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms.

See 2-Methoxyestradiol and Metabolism

Metabolite

In biochemistry, a metabolite is an intermediate or end product of metabolism.

See 2-Methoxyestradiol and Metabolite

Methyl group

In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula (whereas normal methane has the formula). In formulas, the group is often abbreviated as Me.

See 2-Methoxyestradiol and Methyl group

Mitotic inhibitor

A mitotic inhibitor, microtubule inhibitor, or tubulin inhibitor, is a drug that inhibits mitosis, or cell division, and is used in treating cancer, gout, and nail fungus. 2-Methoxyestradiol and mitotic inhibitor are mitotic inhibitors.

See 2-Methoxyestradiol and Mitotic inhibitor

MP-2001

MP-2001, also known as 2,3,4-trimethoxyestra-1,3,5(10)-trien-17β-ol or 2,4-dimethoxyestradiol 3-methyl ether, is a steroid and derivative of estradiol that was described in 1966 and is devoid of estrogenic activity but produces potent analgesic effects in animals. 2-Methoxyestradiol and MP-2001 are Estranes and ethers.

See 2-Methoxyestradiol and MP-2001

Natural product

A natural product is a natural compound or substance produced by a living organism—that is, found in nature.

See 2-Methoxyestradiol and Natural product

Neoplasm

A neoplasm is a type of abnormal and excessive growth of tissue.

See 2-Methoxyestradiol and Neoplasm

Oral administration

| name.

See 2-Methoxyestradiol and Oral administration

Ovarian cancer

Ovarian cancer is a cancerous tumor of an ovary.

See 2-Methoxyestradiol and Ovarian cancer

Prostate cancer

Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder.

See 2-Methoxyestradiol and Prostate cancer

Rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.

See 2-Methoxyestradiol and Rheumatoid arthritis

Sex hormone-binding globulin

Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to androgens and estrogens.

See 2-Methoxyestradiol and Sex hormone-binding globulin

Structural analog

A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.

See 2-Methoxyestradiol and Structural analog

Sulfamic acid

Sulfamic acid, also known as amidosulfonic acid, amidosulfuric acid, aminosulfonic acid, sulphamic acid and sulfamidic acid, is a molecular compound with the formula H3NSO3.

See 2-Methoxyestradiol and Sulfamic acid

Testosterone

Testosterone is the primary male sex hormone and androgen in males.

See 2-Methoxyestradiol and Testosterone

Vasodilation

Vasodilation, also known as vasorelaxation, is the widening of blood vessels.

See 2-Methoxyestradiol and Vasodilation

2-Hydroxyestradiol

2-Hydroxyestradiol (2-OHE2), also known as estra-1,3,5(10)-triene-2,3,17β-triol, is an endogenous steroid, catechol estrogen, and metabolite of estradiol, as well as a positional isomer of estriol. 2-Methoxyestradiol and 2-Hydroxyestradiol are Estranes and human metabolites.

See 2-Methoxyestradiol and 2-Hydroxyestradiol

2-Methoxyestradiol disulfamate

2-Methoxyestradiol disulfamate (developmental code STX-140; also known as 2-methoxyestradiol 3,17β-O,O-bis(sulfamate)) is a synthetic, oral active anti-cancer medication which was previously under development for potential clinical use. 2-Methoxyestradiol and 2-Methoxyestradiol disulfamate are Abandoned drugs, angiogenesis inhibitors, Antineoplastic drugs, Estranes, ethers, human metabolites and microtubule inhibitors.

See 2-Methoxyestradiol and 2-Methoxyestradiol disulfamate

2-Methoxyestriol

2-Methoxyestriol (2-MeO-E3) is an endogenous estrogen metabolite. 2-Methoxyestradiol and 2-Methoxyestriol are Estranes, ethers, human metabolites, Hypolipidemic agents and Phenols.

See 2-Methoxyestradiol and 2-Methoxyestriol

2-Methoxyestrone

2-Methoxyestrone (2-ME1) is an endogenous, naturally occurring methoxylated catechol estrogen and metabolite of estrone that is formed by catechol O-methyltransferase via the intermediate 2-hydroxyestrone. 2-Methoxyestradiol and 2-Methoxyestrone are Estranes, ethers, human metabolites and Phenols.

See 2-Methoxyestradiol and 2-Methoxyestrone

4-Methoxyestradiol

4-Methoxyestradiol (4-ME2) is an endogenous, naturally occurring methoxylated catechol estrogen and metabolite of estradiol that is formed by catechol O-methyltransferase via the intermediate 4-hydroxyestradiol. 2-Methoxyestradiol and 4-Methoxyestradiol are Estranes, ethers and human metabolites.

See 2-Methoxyestradiol and 4-Methoxyestradiol

4-Methoxyestrone

4-Methoxyestrone (4-ME1) is an endogenous, naturally occurring methoxylated catechol estrogen and metabolite of estrone that is formed by catechol O-methyltransferase via the intermediate 4-hydroxyestrone. 2-Methoxyestradiol and 4-Methoxyestrone are Estranes, ethers, human metabolites and Phenols.

See 2-Methoxyestradiol and 4-Methoxyestrone

References

[1] https://en.wikipedia.org/wiki/2-Methoxyestradiol

Also known as 2ME2, Panzem.

Unionpedia is a concept map or semantic network organized like an encyclopedia – dictionary. It gives a brief definition of each concept and its relationships.

This is a giant online mental map that serves as a basis for concept diagrams. It's free to use and each article or document can be downloaded. It's a tool, resource or reference for study, research, education, learning or teaching, that can be used by teachers, educators, pupils or students; for the academic world: for school, primary, secondary, high school, middle, technical degree, college, university, undergraduate, master's or doctoral degrees; for papers, reports, projects, ideas, documentation, surveys, summaries, or thesis. Here is the definition, explanation, description, or the meaning of each significant on which you need information, and a list of their associated concepts as a glossary. Available in English, Spanish, Portuguese, Japanese, Chinese, French, German, Italian, Polish, Dutch, Russian, Arabic, Hindi, Swedish, Ukrainian, Hungarian, Catalan, Czech, Hebrew, Danish, Finnish, Indonesian, Norwegian, Romanian, Turkish, Vietnamese, Korean, Thai, Greek, Bulgarian, Croatian, Slovak, Lithuanian, Filipino, Latvian, Estonian and Slovenian. More languages soon.

The information is based on Wikipedia articles and other Wikimedia projects, and it's available under the Creative Commons Attribution-ShareAlike License.

Unionpedia is not endorsed by or affiliated with the Wikimedia Foundation.

Google Play, Android and the Google Play logo are trademarks of Google Inc.

2-Methoxyestradiol

Table of Contents

See also

Angiogenesis inhibitors

GPER agonists

Hypolipidemic agents

Microtubule inhibitors

Mitotic inhibitors

References