39 relations: Agonist, Androgen receptor, Antidepressant, Anxiolytic, Cell (biology), Cell signaling, Concentration, Cytostasis, Dehydroepiandrosterone, Dihydrotestosterone, Endogeny (biology), Epiandrosterone, Estradiol, Estrogen, Estrogen receptor alpha, Estrogen receptor beta, Female, GABAA receptor, Human, Hypothalamic–pituitary–adrenal axis, Ligand (biochemistry), Male, Metabolite, Molar concentration, Neuron, Nootropic, Oxytocin, Paraventricular nucleus of hypothalamus, Pregnanetriol, Prostate, Prostate cancer, Psychological stress, Serum (blood), Steroid hormone, Testosterone, 17β-Hydroxysteroid dehydrogenase, 3α-Androstanediol, 3β-Hydroxysteroid dehydrogenase, 5α-Reductase.
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.
The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.
Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions.
In chemistry, concentration is the abundance of a constituent divided by the total volume of a mixture.
Cytostasis (cyto – cell; stasis – stoppage) is the inhibition of cell growth and multiplication.
Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone.
Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.
Endogenous substances and processes are those that originate from within an organism, tissue, or cell.
Epiandrosterone, or isoandrosterone, also known as 3β-androsterone, 3β-hydroxy-5α-androstan-17-one, or 5α-androstan-3β-ol-17-one, is a steroid hormone with weak androgenic activity.
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.
Estrogen, or oestrogen, is the primary female sex hormone.
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.
Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen.
Female (♀) is the sex of an organism, or a part of an organism, that produces non-mobile ova (egg cells).
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.
Humans (taxonomically Homo sapiens) are the only extant members of the subtribe Hominina.
The hypothalamic–pituitary–adrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus, the pituitary gland (a pea-shaped structure located below the thalamus), and the adrenal (also called "suprarenal") glands (small, conical organs on top of the kidneys).
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
A male (♂) organism is the physiological sex that produces sperm.
A metabolite is the intermediate end product of metabolism.
Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
Nootropics, also known as smart drugs and cognitive enhancers, are drugs, supplements, and other substances that purport to improve cognitive function, particularly executive functions, memory, creativity, or motivation, in healthy individuals.
Oxytocin (Oxt) is a peptide hormone and neuropeptide.
The paraventricular nucleus (PVN, PVA, or PVH) is a nucleus in the hypothalamus.
Pregnanetriol, or 5β-pregnane-3α,17α,20α-triol is a steroid and inactive metabolite of progesterone.
The prostate (from Ancient Greek προστάτης, prostates, literally "one who stands before", "protector", "guardian") is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals.
Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.
In psychology, stress is a feeling of strain and pressure.
In blood, the serum is the component that is neither a blood cell (serum does not contain white or red blood cells) nor a clotting factor; it is the blood plasma not including the fibrinogens.
A steroid hormone is a steroid that acts as a hormone.
Testosterone is the primary male sex hormone and an anabolic steroid.
17β-Hydroxysteroid dehydrogenases (17β-HSD, HSD17B), also 17-ketosteroid reductases (17-KSR), are a group of alcohol oxidoreductases which catalyze the reduction of 17-ketosteroids and the dehydrogenation of 17β-hydroxysteroids in steroidogenesis and steroid metabolism.
3α-Androstanediol (often abbreviated as 3α-diol), also known as 5α-androstane-3α,17β-diol, is an endogenous inhibitory androstane neurosteroid and weak androgen, and a major metabolite of dihydrotestosterone (DHT).
3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) is an enzyme that catalyzes the biosynthesis of progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.
5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.