34 relations: Alexander Shulgin, Appetite, CYP2D6, CYP3A4, Disseminated intravascular coagulation, Dopamine, Drug possession, Empathogen–entactogen, Federal Analogue Act, Fenfluramine, Hyperthermia, Hypertonia, Hypotension, Injection (medicine), Insufflation (medicine), Kidney, Lacing (drugs), Liver, MDMA, Monoamine releasing agent, Mouth, Mydriasis, Norepinephrine, Para-Methoxy-N-ethylamphetamine, PiHKAL, Psychoactive drug, Rectal administration, Reuptake inhibitor, Rhabdomyolysis, Serotonin, Substituted amphetamine, Substituted methylenedioxyphenethylamine, Tachycardia, 3-Fluoroethamphetamine.
Alexander Theodore "Sasha" Shulgin (June 17, 1925 June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author.
Appetite is the desire to eat food, sometimes due to hunger.
Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.
Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.
Disseminated intravascular coagulation (DIC) is a condition in which blood clots form throughout the body, blocking small blood vessels.
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
Drug possession is the crime of having one or more illegal drugs in one's possession, either for personal use, distribution, sale or otherwise.
Empathogens or entactogens are a class of psychoactive drugs that produce experiences of emotional communion, oneness, relatedness, emotional openness—that is, empathy or sympathy—as particularly observed and reported for experiences with 3,4- Methylenedioxymethamphetamine (MDMA).
The Federal Analogue Act,, is a section of the United States Controlled Substances Act passed in 1986 which allowed any chemical "substantially similar" to a controlled substance listed in Schedule I or II to be treated as if it were also listed in those schedules, but only if intended for human consumption.
Fenfluramine, formerly sold under the brand name Pondimin among others, is an appetite suppressant which was used to treat obesity and is now no longer marketed.
Hyperthermia is elevated body temperature due to failed thermoregulation that occurs when a body produces or absorbs more heat than it dissipates.
Hypertonia is a term sometimes used synonymously with spasticity and rigidity in the literature surrounding damage to the central nervous system, namely upper motor neuron lesions.
Hypotension is low blood pressure, especially in the arteries of the systemic circulation.
Injection (often referred to as a "shot" in US English, or a "jab" in UK English) is the act of putting a liquid, especially a drug, into a person's body using a needle (usually a hypodermic needle) and a syringe.
Insufflation (lit) is the act of blowing something (such as a gas, powder, or vapor) into a body cavity.
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
Lacing is the act of adding one or more substances to another.
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E), is a psychoactive drug used primarily as a recreational drug.
A monoamine releasing agent (MRA), or simply monoamine releaser, is a drug that induces the release of a monoamine neurotransmitter from the presynaptic neuron into the synapse, leading to an increase in the extracellular concentrations of the neurotransmitter.
In animal anatomy, the mouth, also known as the oral cavity, buccal cavity, or in Latin cavum oris, is the opening through which many animals take in food and issue vocal sounds.
Mydriasis is the dilation of the pupil, usually having a non-physiological cause, or sometimes a physiological pupillary response.
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
para-Methoxyethylamphetamine (PMEA), is a stimulant drug related to PMA.
PiHKAL: A Chemical Love Story is a book by Dr.
A psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.
Rectal administration uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels,The rectum has numerous blood vessels available to absorb drugs.
A reuptake inhibitor (RI) is a type of drug known as a reuptake modulator that inhibits the plasmalemmal transporter-mediated reuptake of a neurotransmitter from the synapse into the pre-synaptic neuron.
Rhabdomyolysis is a condition in which damaged skeletal muscle breaks down rapidly.
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
Substituted amphetamines are a class of compounds based upon the amphetamine structure; it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents.
Substituted methylenedioxy- phenethylamines (MDxx) are a large chemical class of derivatives of the phenethylamines, which includes many psychoactive drugs that act as entactogens, psychedelics, and/or stimulants, as well as entheogens.
Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.
3-Fluoroethamphetamine (3-FEA) is a stimulant drug of the amphetamine class which acts as a releasing agent of the monoamine neurotransmitters norepinephrine, dopamine and serotonin.
3,4-Methylendioxy-n-Ethylamphetamine, 3,4-Methylenedioxyethylamphetamine, 3,4-methylenedioxy-N-ethylamphetamine, 3,4-methylenedioxyethylamphetamine, Methylenedioxy-N-ethylamphetamine, Methylenedioxyethamphetamine, Methylenedioxyethylamphetamine.