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19 relations: Acetyl-CoA, Apicomplexa, Bacteria, Dimethylallyl pyrophosphate, Dimethylallyltranstransferase, Geranyl pyrophosphate, Isomer, Isopentenyl-diphosphate delta isomerase, Malaria, Mevalonate pathway, Non-mevalonate pathway, Plant, Plastid, Protozoa, Squalene, Terpene, Terpenoid, (E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate, 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase.
Acetyl-CoA
Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism.
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Apicomplexa
The Apicomplexa (also called Apicomplexia) are a large phylum of parasitic alveolates.
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Bacteria
Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.
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Dimethylallyl pyrophosphate
Dimethylallyl pyrophosphate (DMAPP; or alternatively, dimethylallyl diphosphate (DMADP); also isoprenyl pyrophosphate) is an isoprenoid precursor.
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Dimethylallyltranstransferase
Dimethylallyltranstransferase (DMATT), also known as farnesylpyrophosphate synthase (FPPS) or as farnesyldiphosphate synthase (FDPS), is an enzyme that catalyzes the transformation of dimethylallylpyrophosphate (DMAPP) and isopentenyl pyrophosphate (IPP) into farnesylpyrophosphate (FPP).
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Geranyl pyrophosphate
Geranyl pyrophosphate (GPP), also known as geranyl diphosphate (GDP), is an intermediate in the HMG-CoA reductase pathway used by organisms in the biosynthesis of farnesyl pyrophosphate, geranylgeranyl pyrophosphate.
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Isomer
An isomer (from Greek ἰσομερής, isomerès; isos.
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Isopentenyl-diphosphate delta isomerase
Isopentenyl pyrophosphate isomerase (IPP isomerase), also known as Isopentenyl-diphosphate delta isomerase, is an isomerase that catalyzes the conversion of the relatively un-reactive isopentenyl pyrophosphate (IPP) to the more-reactive electrophile dimethylallyl pyrophosphate (DMAPP).
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Malaria
Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.
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Mevalonate pathway
The mevalonate pathway, also known as the isoprenoid pathway or HMG-CoA reductase pathway is an essential metabolic pathway present in eukaryotes, archaea, and some bacteria.
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Non-mevalonate pathway
The non-mevalonate pathway—also appearing as the mevalonate-independent pathway and the 2-C-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate (MEP/DOXP) pathway—is an alternative metabolic pathway for the biosynthesis of the isoprenoid precursors isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP).
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Plant
Plants are mainly multicellular, predominantly photosynthetic eukaryotes of the kingdom Plantae.
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Plastid
The plastid (Greek: πλαστός; plastós: formed, molded – plural plastids) is a double-membrane organelle found in the cells of plants, algae, and some other eukaryotic organisms.
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Protozoa
Protozoa (also protozoan, plural protozoans) is an informal term for single-celled eukaryotes, either free-living or parasitic, which feed on organic matter such as other microorganisms or organic tissues and debris.
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Squalene
Squalene is a natural 30-carbon organic compound originally obtained for commercial purposes primarily from shark liver oil (hence its name, as Squalus is a genus of sharks), although plant sources (primarily vegetable oils) are now used as well, including amaranth seed, rice bran, wheat germ, and olives.
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Terpene
Terpenes are a large and diverse class of organic compounds, produced by a variety of plants, particularly conifers, and by some insects.
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Terpenoid
The terpenoids, sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenes.
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(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate
(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP or HMB-PP) is an intermediate of the MEP pathway (non-mevalonate pathway) of isoprenoid biosynthesis.
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4-Hydroxy-3-methylbut-2-enyl diphosphate reductase
4-Hydroxy-3-methylbut-2-enyl diphosphate reductase (isopentenyl-diphosphate:NADP+ oxidoreductase, LytB, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase, HMBPP reductase, IspH, LytB/IspH) is an enzyme in the non-mevalonate pathway.
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