44 relations: Alpha helix, Amide, Amine, Amino acid, Atom, Beta bend ribbon, Beta sheet, Beta turn, Biomolecular structure, Carbonyl group, Cold Spring Harbor Laboratory Press, Collagen, Condensation reaction, CRC Press, Dihedral angle, Francis Crick, Gibbs free energy, Globular protein, Helix, Hemoglobin, Hydrogen bond, James Watson, John Kendrew, Journal of Molecular Biology, Laboratory of Molecular Biology, Lawrence Bragg, Linus Pauling, Max Perutz, Medical Research Council (United Kingdom), Myoglobin, Nature (journal), Nucleic acid double helix, Pi helix, Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the Royal Society, Protein, Protein Science, Scientific American, The Journal of General Physiology, Transmembrane domain, Trends (journals), University of Cambridge, Voltage-gated potassium channel, World Scientific.
The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.
An amide (or or), also known as an acid amide, is a compound with the functional group RnE(O)xNR′2 (R and R′ refer to H or organic groups).
In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
An atom is the smallest constituent unit of ordinary matter that has the properties of a chemical element.
The beta bend ribbon, or beta-bend ribbon, is a structural feature in polypeptides and proteins.
The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.
A β turn is a type of non-regular secondary structure in proteins that causes a change in direction of the polypeptide chain.
Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to its function.
In organic chemistry, a carbonyl group is a functional group composed of a carbon atom double-bonded to an oxygen atom: C.
Cold Spring Harbor Laboratory Press was founded in 1933 to aid in Cold Spring Harbor Laboratory's purpose of furthering the advance and spread of scientific knowledge.
Collagen is the main structural protein in the extracellular space in the various connective tissues in animal bodies.
A condensation reaction is a class of an organic addition reaction that proceeds in a step-wise fashion to produce the addition product, usually in equilibrium, and a water molecule (hence named condensation).
The CRC Press, LLC is a publishing group based in the United States that specializes in producing technical books.
A dihedral angle is the angle between two intersecting planes.
Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was a British molecular biologist, biophysicist, and neuroscientist, most noted for being a co-discoverer of the structure of the DNA molecule in 1953 with James Watson, work which was based partly on fundamental studies done by Rosalind Franklin, Raymond Gosling and Maurice Wilkins.
In thermodynamics, the Gibbs free energy (IUPAC recommended name: Gibbs energy or Gibbs function; also known as free enthalpy to distinguish it from Helmholtz free energy) is a thermodynamic potential that can be used to calculate the maximum of reversible work that may be performed by a thermodynamic system at a constant temperature and pressure (isothermal, isobaric).
Globular proteins or spheroproteins are spherical ("globe-like") proteins and are one of the common protein types (the others being fibrous, disordered and membrane proteins).
A helix, plural helixes or helices, is a type of smooth space curve, i.e. a curve in three-dimensional space.
Hemoglobin (American) or haemoglobin (British); abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates (with the exception of the fish family Channichthyidae) as well as the tissues of some invertebrates.
A hydrogen bond is a partially electrostatic attraction between a hydrogen (H) which is bound to a more electronegative atom such as nitrogen (N), oxygen (O), or fluorine (F), and another adjacent atom bearing a lone pair of electrons.
James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist and zoologist, best known as one of the co-discoverers of the structure of DNA in 1953 with Francis Crick and Rosalind Franklin.
Sir John Cowdery Kendrew, (24 March 1917 – 23 August 1997) was an English biochemist and crystallographer who shared the 1962 Nobel Prize in Chemistry with Max Perutz; their group in the Cavendish Laboratory investigated the structure of heme-containing proteins.
The Journal of Molecular Biology is a peer-reviewed scientific journal published weekly by Elsevier.
The Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) is a research institute in Cambridge, England, involved in the revolution in molecular biology which occurred in the 1950–60s, since then it remains a major medical research laboratory with a much broader focus.
Sir William Lawrence Bragg, (31 March 1890 – 1 July 1971) was an Australian-born British physicist and X-ray crystallographer, discoverer (1912) of Bragg's law of X-ray diffraction, which is basic for the determination of crystal structure.
Linus Carl Pauling (February 28, 1901 – August 19, 1994) was an American chemist, biochemist, peace activist, author, educator, and husband of American human rights activist Ava Helen Pauling.
Max Ferdinand Perutz (19 May 1914 – 6 February 2002) was an Austrian-born British molecular biologist, who shared the 1962 Nobel Prize for Chemistry with John Kendrew, for their studies of the structures of haemoglobin and myoglobin.
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom.
Myoglobin (symbol Mb or MB) is an iron- and oxygen-binding protein found in the muscle tissue of vertebrates in general and in almost all mammals.
Nature is a British multidisciplinary scientific journal, first published on 4 November 1869.
In molecular biology, the term double helix refers to the structure formed by double-stranded molecules of nucleic acids such as DNA.
A pi helix (or π-helix) is a type of secondary structure found in proteins.
Proceedings of the National Academy of Sciences of the United States of America (PNAS) is the official scientific journal of the National Academy of Sciences, published since 1915.
Proceedings of the Royal Society is the parent title of two scientific journals published by the Royal Society.
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
Protein Science is a peer-reviewed scientific journal covering research on the structure, function, and biochemical significance of proteins, their role in molecular and cell biology, genetics, and evolution, and their regulation and mechanisms of action.
Scientific American (informally abbreviated SciAm) is an American popular science magazine.
Journal of General Physiology is a peer-reviewed scientific journal published by Rockefeller University Press.
Transmembrane domain usually denotes a transmembrane segment of single alpha helix of a transmembrane protein.
Trends is a series of scientific journals owned by Elsevier that publish review articles in a range of areas of biology.
The University of Cambridge (informally Cambridge University)The corporate title of the university is The Chancellor, Masters, and Scholars of the University of Cambridge.
Voltage-gated potassium channels (VGKCs) are transmembrane channels specific for potassium and sensitive to voltage changes in the cell's membrane potential.
World Scientific Publishing is an academic publisher of scientific, technical, and medical books and journals headquartered in Singapore.