54 relations: Adrenal gland, Aldosterone, Androgen, Androstadienol, Androstadienone, Androstenediol, Androstenedione, Azastene, Biosynthesis, Catalysis, Chemical reaction, Congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency, Corticosteroid, Cortisol, Cyanoketone, Cytochrome P450, Dehydroepiandrosterone, Enzyme, Epostane, Estrogen, Gene, Glucocorticoid, HELLP syndrome, Hormone, HSD3B1, HSD3B2, Hydrogen ion, Hydroxysteroid, Infant respiratory distress syndrome, Isozyme, List of enzymes, Lung, Medrogestone, Medroxyprogesterone acetate, Mineralocorticoid, Nicotinamide adenine dinucleotide, Oxidoreductase, Placental abruption, Pre-eclampsia, Pregnenolone, Preterm birth, Product (chemistry), Progesterone, Pulmonary alveolus, Pulmonary surfactant, Steroid, Steroidogenic enzyme, Substrate (chemistry), Surface tension, Testosterone, ..., Trilostane, 17α-Hydroxypregnenolone, 17α-Hydroxyprogesterone, 3α-Hydroxysteroid dehydrogenase. Expand index (4 more) » « Shrink index
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.
Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
Androstadienol, or androsta-5,16-dien-3β-ol, is an endogenous steroid, pheromone, and chemical intermediate to several other pheromones that is found in the sweat of both men and women.
Androstadienone, also known as androsta-4,16-dien-3-one, is an endogenous steroid that has been described as having potent pheromone-like activities in humans.
Androstenediol, or 5-androstenediol (abbreviated as A5 or Δ5-diol), also known as androst-5-ene-3β,17β-diol, is an endogenous weak androgen and estrogen steroid hormone and intermediate in the biosynthesis of testosterone from dehydroepiandrosterone (DHEA).
Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).
Azastene (INN, USAN) (developmental code name WIN-17625) is a steroidogenesis inhibitor described as a contraceptive and abortifacient which was never marketed.
Biosynthesis (also called anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.
Catalysis is the increase in the rate of a chemical reaction due to the participation of an additional substance called a catalysthttp://goldbook.iupac.org/C00876.html, which is not consumed in the catalyzed reaction and can continue to act repeatedly.
A chemical reaction is a process that leads to the transformation of one set of chemical substances to another.
Congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency is an uncommon form of congenital adrenal hyperplasia (CAH) resulting from a mutation in the gene for one of the key enzymes in cortisol synthesis by the adrenal gland, 3β-hydroxysteroid dehydrogenase (3β-HSD) type II (HSD3B2).
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.
Cortisol is a steroid hormone, in the glucocorticoid class of hormones.
Cyanoketone, also known as 2α-cyano-4,4',17α-trimethylandrost-5-en-17β-ol-3-one, is a synthetic androstane steroid and a steroidogenesis inhibitor which is used in scientific research.
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone.
Enzymes are macromolecular biological catalysts.
Epostane (INN, USAN, BAN) (developmental code name WIN-32729) is an inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD) that was developed as an contraceptive, abortifacient, and oxytocic drug but was never marketed.
Estrogen, or oestrogen, is the primary female sex hormone.
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.
HELLP syndrome is a well-known variant of pre-eclampsia pregnancy complication.
A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.
HSD3B1 is a human gene that encodes for a 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type I or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1.
HSD3B2 is a human gene that encodes for 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type II or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2.
A hydrogen ion is created when a hydrogen atom loses or gains an electron.
A hydroxysteroid is a molecule derived from a steroid with a hydrogen replaced with a hydroxy group.
Infant respiratory distress syndrome (IRDS), also called neonatal respiratory distress syndrome (NRDS), respiratory distress syndrome of newborn, or increasingly surfactant deficiency disorder (SDD), and previously called hyaline membrane disease (HMD), is a syndrome in premature infants caused by developmental insufficiency of pulmonary surfactant production and structural immaturity in the lungs.
Isozymes (also known as isoenzymes or more generally as multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction.
This page lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission numbering system.
The lungs are the primary organs of the respiratory system in humans and many other animals including a few fish and some snails.
Medrogestone, sold under the brand name Colprone among others, is a progestin medication which has been used in menopausal hormone therapy and in the treatment of gynecological disorders.
Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type.
Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones.
Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells.
In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule, the reductant, also called the electron donor, to another, the oxidant, also called the electron acceptor.
Placental abruption is when the placenta separates early from the uterus, in other words separates before childbirth.
Pre-eclampsia (PE) is a disorder of pregnancy characterized by the onset of high blood pressure and often a significant amount of protein in the urine.
Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids.
Preterm birth, also known as premature birth, is the birth of a baby at fewer than 37 weeks gestational age.
Products are the species formed from chemical reactions.
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.
A pulmonary alveolus (plural: alveoli, from Latin alveolus, "little cavity") is a hollow cavity found in the lung parenchyma, and is the basic unit of ventilation.
Pulmonary surfactant is a surface-active lipoprotein complex (phospholipoprotein) formed by type II alveolar cells.
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
Steroidogenic enzymes, or steroid-metabolizing enzymes, are enzymes that are involved in steroidogenesis and steroid metabolism.
In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.
Surface tension is the elastic tendency of a fluid surface which makes it acquire the least surface area possible.
Testosterone is the primary male sex hormone and an anabolic steroid.
Trilostane is a steroidogenesis inhibitor which is used in the treatment of Cushing's syndrome.
17α-Hydroxypregnenolone is a pregnane (C21) steroid that is obtained by hydroxylation of pregnenolone at the C17α position.
17α-Hydroxyprogesterone (17α-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone related to progesterone.
3α-hydroxysteroid dehydrogenase (3α-HSD), also known as aldo-keto reductase family 1 member C4, is an enzyme that in humans is encoded by the AKR1C4 gene.
3 beta-hydroxysteroid dehydrogenase, 3-beta HSD, 3-beta-HSD, 3-beta-hydroxysteroid dehydrogenase, 3-β-Hydroxysteroid dehydrogenase, 3-β-hydroxysteroid dehydrogenase, 3Beta Hydroxysteroid dehydrogenase, 3b-HSD, 3b-hydroxy-D5-steroid dehydrogenase, 3beta-Hydroxysteroid dehydrogenase, 3beta-hydroxy-Delta5-steroid dehydrogenase, 3beta-hydroxy-Delta5-steroid:NAD+ 3-oxidoreductase, 3beta-hydroxysteroid dehydrogenase, 3β-HSD, 3β-Hydroxysteroid dehydrogenases, 3β-hydroxysteroid dehydrogenase, 3β-hydroxysteroid dehydrogenase/Δ-5-4 isomerase, 3βHSD II, Delta 4-5 isomerase, Delta 5-4 isomerase, EC 126.96.36.199, Progesterone reductase.