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4-Androstadienol

Index 4-Androstadienol

4-Androstadienol (developmental code name PH94B; tentative commercial name Aloradine or Aloradine IN), also known as 4,16-androstadien-3β-ol, is a pherine or synthetic pheromone which is under development by Pherin Pharmaceuticals, Inc. [1]

26 relations: Allosteric modulator, Androstadienol, Androstadienone, Androstenol, Androstenone, Anxiolytic, Cell (biology), Clinical trial, EC50, Endogeny (biology), GABAA receptor, Generalized anxiety disorder, Ligand (biochemistry), List of investigational anxiolytics, Molar concentration, Nasal administration, Nasal spray, Organic compound, Phases of clinical research, Pherine, Pheromone, Pro re nata, Social anxiety disorder, Steroid hormone receptor, Structural isomer, Vomeronasal receptor.

Allosteric modulator

In biochemistry and pharmacology, an allosteric modulator (allo- from the Greek meaning "other") is a substance which indirectly influences (modulates) the effects of a primary ligand that directly activates or deactivates the function of a target protein.

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Androstadienol

Androstadienol, or androsta-5,16-dien-3β-ol, is an endogenous steroid, pheromone, and chemical intermediate to several other pheromones that is found in the sweat of both men and women.

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Androstadienone

Androstadienone, also known as androsta-4,16-dien-3-one, is an endogenous steroid that has been described as having potent pheromone-like activities in humans.

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Androstenol

Androstenol, also known as 5α-androst-16-en-3α-ol (shortened to 3α,5α-androstenol or 3α-androstenol), is a steroidal pheromone and neurosteroid in humans and other mammals, notably pigs.

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Androstenone

No description.

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Anxiolytic

An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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EC50

Half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time.

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Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

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GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

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Generalized anxiety disorder

Generalized anxiety disorder (GAD) is an anxiety disorder characterized by excessive, uncontrollable and often irrational worry, that is, apprehensive expectation about events or activities.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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List of investigational anxiolytics

This is a list of investigational anxiolytics, or anxiolytics that are currently under development for clinical use but are not yet approved.

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Molar concentration

Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.

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Nasal administration

Nasal administration is a route of administration in which drugs are insufflated through the nose.

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Nasal spray

Nasal sprays, or nasal drops, are used as local treatments for conditions such as nasal congestion and allergic rhinitis.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Phases of clinical research

The phases of clinical research are the steps in which scientists do experiments with a health intervention in an attempt to find enough evidence for a process which would be useful as a medical treatment.

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Pherine

Pherines, also known as vomeropherines, are odorless synthetic neuroactive steroids that engage nasal chemosensory receptors and induce dose-dependent and reversible pharmacological and behavioral effects.

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Pheromone

A pheromone (from Ancient Greek φέρω phero "to bear" and hormone, from Ancient Greek ὁρμή "impetus") is a secreted or excreted chemical factor that triggers a social response in members of the same species.

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Pro re nata

Pro re nata is a Latin phrase meaning in the circumstances or as the circumstance arises (literally "for the thing born").

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Social anxiety disorder

Social anxiety disorder (SAD), also known as social phobia, is an anxiety disorder characterized by a significant amount of fear in one or more social situations, causing considerable distress and impaired ability to function in at least some parts of daily life.

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Steroid hormone receptor

Steroid hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells.

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Structural isomer

Structural isomerism, or constitutional isomerism (per IUPAC), is a form of isomerism in which molecules with the same molecular formula have different bonding patterns and atomic organization, as opposed to stereoisomerism, in which molecular bonds are always in the same order and only spatial arrangement differs.

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Vomeronasal receptor

Vomeronasal receptors are a class of olfactory receptors that putatively function as receptors for pheromones.

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Redirects here:

(3β)-Androsta-4,16-dien-3-ol, (3β)-androsta-4,16-dien-3-ol, 3β-Androsta-4,16-dien-3-ol, 3β-androsta-4,16-dien-3-ol, 4,16-Androstadien-3β-ol, 4,16-androstadien-3β-ol, 4-androstadienol, Aloradine, Aloradine IN, Androsta-4,16-dien-3β-ol, PH 94B, PH-94B, PH94B.

References

[1] https://en.wikipedia.org/wiki/4-Androstadienol

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