Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Install
Faster access than browser!
 

4-Hydroxynonenal

Index 4-Hydroxynonenal

4-Hydroxynonenal, or 4-hydroxy-2-nonenal or 4-HNE or HNE, (9162), is an α,β-unsaturated hydroxyalkenal that is produced by lipid peroxidation in cells. [1]

45 relations: Acute respiratory distress syndrome, Acyl group, Aldehyde, Aldehyde dehydrogenase, Aldose reductase, Alzheimer's disease, Apoptosis, Arachidonic acid, Atherosclerosis, Brain, Cancer, Cardiovascular disease, Caspase, Cataract, Chain reaction, Cooking oil, Cytochrome c, Diabetes mellitus, Diet (nutrition), Epidemiology, Fatty acid, Glucic acid, Glutathione, Glutathione S-transferase, Heat shock, Hydrogen peroxide, Inflammation, Ischemia, Linoleic acid, Lipid, Lipid peroxidation, Malondialdehyde, Michaelis–Menten kinetics, Molar concentration, Molecular Aspects of Medicine, Necrosis, Neurodegeneration, Omega-6 fatty acid, Oxidative stress, Polyunsaturated fat, Signal transduction, Trans-4,5-Epoxy-(E)-2-decenal, Ultraviolet, 13-Hydroxyoctadecadienoic acid, 15-Hydroxyeicosatetraenoic acid.

Acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is a medical condition occurring in critically ill or critically wounded patients characterized by widespread inflammation in the lungs.

New!!: 4-Hydroxynonenal and Acute respiratory distress syndrome · See more »

Acyl group

An acyl group is a moiety derived by the removal of one or more hydroxyl groups from an oxoacid, including inorganic acids.

New!!: 4-Hydroxynonenal and Acyl group · See more »

Aldehyde

An aldehyde or alkanal is an organic compound containing a functional group with the structure −CHO, consisting of a carbonyl center (a carbon double-bonded to oxygen) with the carbon atom also bonded to hydrogen and to an R group, which is any generic alkyl or side chain.

New!!: 4-Hydroxynonenal and Aldehyde · See more »

Aldehyde dehydrogenase

Aldehyde dehydrogenases are a group of enzymes that catalyse the oxidation of aldehydes.

New!!: 4-Hydroxynonenal and Aldehyde dehydrogenase · See more »

Aldose reductase

In enzymology, aldose reductase (or aldehyde reductase) is a cytosolic NADPH-dependent oxidoreductase that catalyzes the reduction of a variety of aldehydes and carbonyls, including monosaccharides.

New!!: 4-Hydroxynonenal and Aldose reductase · See more »

Alzheimer's disease

Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.

New!!: 4-Hydroxynonenal and Alzheimer's disease · See more »

Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

New!!: 4-Hydroxynonenal and Apoptosis · See more »

Arachidonic acid

Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6).

New!!: 4-Hydroxynonenal and Arachidonic acid · See more »

Atherosclerosis

Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.

New!!: 4-Hydroxynonenal and Atherosclerosis · See more »

Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

New!!: 4-Hydroxynonenal and Brain · See more »

Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

New!!: 4-Hydroxynonenal and Cancer · See more »

Cardiovascular disease

Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels.

New!!: 4-Hydroxynonenal and Cardiovascular disease · See more »

Caspase

Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing essential roles in programmed cell death (including apoptosis, pyroptosis and necroptosis) and inflammation.

New!!: 4-Hydroxynonenal and Caspase · See more »

Cataract

A cataract is a clouding of the lens in the eye which leads to a decrease in vision.

New!!: 4-Hydroxynonenal and Cataract · See more »

Chain reaction

A chain reaction is a sequence of reactions where a reactive product or by-product causes additional reactions to take place.

New!!: 4-Hydroxynonenal and Chain reaction · See more »

Cooking oil

Cooking oil is plant, animal, or synthetic fat used in frying, baking, and other types of cooking.

New!!: 4-Hydroxynonenal and Cooking oil · See more »

Cytochrome c

The cytochrome complex, or cyt c is a small hemeprotein found loosely associated with the inner membrane of the mitochondrion.

New!!: 4-Hydroxynonenal and Cytochrome c · See more »

Diabetes mellitus

Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.

New!!: 4-Hydroxynonenal and Diabetes mellitus · See more »

Diet (nutrition)

In nutrition, diet is the sum of food consumed by a person or other organism.

New!!: 4-Hydroxynonenal and Diet (nutrition) · See more »

Epidemiology

Epidemiology is the study and analysis of the distribution (who, when, and where) and determinants of health and disease conditions in defined populations.

New!!: 4-Hydroxynonenal and Epidemiology · See more »

Fatty acid

In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with a long aliphatic chain, which is either saturated or unsaturated.

New!!: 4-Hydroxynonenal and Fatty acid · See more »

Glucic acid

Glucic acid is an acid produced by the action of acids on cane-sugar or of alkalis on glucose.

New!!: 4-Hydroxynonenal and Glucic acid · See more »

Glutathione

Glutathione (GSH) is an important antioxidant in plants, animals, fungi, and some bacteria and archaea.

New!!: 4-Hydroxynonenal and Glutathione · See more »

Glutathione S-transferase

Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification.

New!!: 4-Hydroxynonenal and Glutathione S-transferase · See more »

Heat shock

In biochemistry, heat shock is the effect of subjecting a cell to a temperature that is greater than the optimal temperature range of function of the cell.

New!!: 4-Hydroxynonenal and Heat shock · See more »

Hydrogen peroxide

Hydrogen peroxide is a chemical compound with the formula.

New!!: 4-Hydroxynonenal and Hydrogen peroxide · See more »

Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

New!!: 4-Hydroxynonenal and Inflammation · See more »

Ischemia

Ischemia or ischaemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).

New!!: 4-Hydroxynonenal and Ischemia · See more »

Linoleic acid

Linoleic acid (LA), a carboxylic acid, is a polyunsaturated omega-6 fatty acid, an 18-carbon chain with two double bonds in cis configuration.

New!!: 4-Hydroxynonenal and Linoleic acid · See more »

Lipid

In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.

New!!: 4-Hydroxynonenal and Lipid · See more »

Lipid peroxidation

Lipid peroxidation is the oxidative degradation of lipids.

New!!: 4-Hydroxynonenal and Lipid peroxidation · See more »

Malondialdehyde

Malondialdehyde (MDA) is the organic compound with the nominal formula CH2(CHO)2.

New!!: 4-Hydroxynonenal and Malondialdehyde · See more »

Michaelis–Menten kinetics

Michaelis–Menten saturation curve for an enzyme reaction showing the relation between the substrate concentration and reaction rate. In biochemistry, Michaelis–Menten kinetics is one of the best-known models of enzyme kinetics.

New!!: 4-Hydroxynonenal and Michaelis–Menten kinetics · See more »

Molar concentration

Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.

New!!: 4-Hydroxynonenal and Molar concentration · See more »

Molecular Aspects of Medicine

Molecular Aspects of Medicine is a peer-reviewed medical journal for clinicians of all relevant specialities and biomedical scientists working in areas from biochemistry and molecular and cell biology to physiology, pharmacology and pathology.

New!!: 4-Hydroxynonenal and Molecular Aspects of Medicine · See more »

Necrosis

Necrosis (from the Greek νέκρωσις "death, the stage of dying, the act of killing" from νεκρός "dead") is a form of cell injury which results in the premature death of cells in living tissue by autolysis.

New!!: 4-Hydroxynonenal and Necrosis · See more »

Neurodegeneration

Neurodegeneration is the progressive loss of structure or function of neurons, including death of neurons.

New!!: 4-Hydroxynonenal and Neurodegeneration · See more »

Omega-6 fatty acid

Omega-6 fatty acids (also referred to as ω-6 fatty acids or n-6 fatty acids) are a family of polyunsaturated fatty acids that have in common a final carbon-carbon double bond in the ''n''-6 position, that is, the sixth bond, counting from the methyl end.

New!!: 4-Hydroxynonenal and Omega-6 fatty acid · See more »

Oxidative stress

Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage.

New!!: 4-Hydroxynonenal and Oxidative stress · See more »

Polyunsaturated fat

Polyunsaturated fats are fats in which the constituent hydrocarbon chain possesses two or more carbon–carbon double bonds.

New!!: 4-Hydroxynonenal and Polyunsaturated fat · See more »

Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.

New!!: 4-Hydroxynonenal and Signal transduction · See more »

Trans-4,5-Epoxy-(E)-2-decenal

trans-4,5-Epoxy-(E)-2-decenal is an oxygenated α,β-unsaturated aldehyde found in mammalian blood that gives blood its characteristic metallic odor.

New!!: 4-Hydroxynonenal and Trans-4,5-Epoxy-(E)-2-decenal · See more »

Ultraviolet

Ultraviolet (UV) is electromagnetic radiation with a wavelength from 10 nm to 400 nm, shorter than that of visible light but longer than X-rays.

New!!: 4-Hydroxynonenal and Ultraviolet · See more »

13-Hydroxyoctadecadienoic acid

13-Hydroxyoctadecadienoic acid (13-HODE) is the commonly used term for 13(S)-hydroxy-9Z,11E-octadecadienoic acid (13(S)-HODE).

New!!: 4-Hydroxynonenal and 13-Hydroxyoctadecadienoic acid · See more »

15-Hydroxyeicosatetraenoic acid

15-Hydroxyeicosatetraenoic acid (also termed 15-HETE, 15(S)-HETE, and 15S-HETE) is an eicosanoid, i.e. a metabolite of arachidonic acid.

New!!: 4-Hydroxynonenal and 15-Hydroxyeicosatetraenoic acid · See more »

Redirects here:

4-HNE, 4-Hydroxy-2-nonenal, 4-hydroxy-2-nonenal, 4-hydroxynonenal, Trans-2-noneal.

References

[1] https://en.wikipedia.org/wiki/4-Hydroxynonenal

OutgoingIncoming
Hey! We are on Facebook now! »