57 relations: Acid dissociation constant, Aldehyde, Aldimine, Aldol reaction, Alpha helix, Amino acid, Antimalarial medication, Arginine, Aspartate transaminase, Beta sheet, Binding site, Cation–pi interaction, Chemotherapy, Chloroplast, Cofactor (biochemistry), Cytoplasm, Dehydration reaction, Enzyme, Enzyme inhibitor, Escherichia coli, Eukaryote, Evolution, Folate, Formaldehyde, Geobacillus stearothermophilus, Glycine, Hemiaminal, Lone pair, Lysine, Malaria, Methylene bridge, Mitochondrion, N-terminus, NMDA receptor, Nucleophile, Pemetrexed, Pharmacokinetics, Plasmodium, Prokaryote, Proline, Protein domain, Protein subunit, Proton, Pyridoxal phosphate, Schiff base, Serine, Smith–Magenis syndrome, Spontaneous process, Stacking (chemistry), Substrate (chemistry), ..., Tetrahydrofolic acid, Tetramer, Threonine, Tyrosine, Vitamin B6, 10-Formyltetrahydrofolate, 5,10-Methylenetetrahydrofolate. Expand index (7 more) »
Acid dissociation constant
An acid dissociation constant, Ka, (also known as acidity constant, or acid-ionization constant) is a quantitative measure of the strength of an acid in solution.
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Aldehyde
An aldehyde or alkanal is an organic compound containing a functional group with the structure −CHO, consisting of a carbonyl center (a carbon double-bonded to oxygen) with the carbon atom also bonded to hydrogen and to an R group, which is any generic alkyl or side chain.
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Aldimine
In organic chemistry, an aldimine is an imine that is an analog of an aldehyde.
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Aldol reaction
The aldol reaction is a means of forming carbon–carbon bonds in organic chemistry.
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Alpha helix
The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.
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Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Antimalarial medication
Antimalarial medications, also known as antimalarials, are designed to prevent or cure malaria.
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Arginine
Arginine (symbol Arg or R) is an α-amino acid that is used in the biosynthesis of proteins.
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Aspartate transaminase
Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or serum glutamic oxaloacetic transaminase (SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme that was first described by Arthur Karmen and colleagues in 1954.
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Beta sheet
The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.
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Binding site
In biochemistry, a binding site is a region on a protein or piece of DNA or RNA to which ligands (specific molecules and/or ions) may form a chemical bond.
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Cation–pi interaction
Cation–π interaction is a noncovalent molecular interaction between the face of an electron-rich π system (e.g. benzene, ethylene, acetylene) and an adjacent cation (e.g. Li+, Na+).
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Chloroplast
Chloroplasts are organelles, specialized compartments, in plant and algal cells.
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Cofactor (biochemistry)
A cofactor is a non-protein chemical compound or metallic ion that is required for an enzyme's activity.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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Dehydration reaction
In chemistry and the biological sciences, a dehydration reaction, also known as Zimmer's hydrogenesis, is a chemical reaction that involves the loss of a water molecule from the reacting molecule.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Enzyme inhibitor
4QI9) An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.
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Escherichia coli
Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Evolution
Evolution is change in the heritable characteristics of biological populations over successive generations.
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Folate
Folate, distinct forms of which are known as folic acid, folacin, and vitamin B9, is one of the B vitamins.
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Formaldehyde
No description.
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Geobacillus stearothermophilus
Geobacillus stearothermophilus (basonym Bacillus stearothermophilus) is a rod-shaped, Gram-positive bacterium and a member of the division Firmicutes.
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Glycine
Glycine (symbol Gly or G) is the amino acid that has a single hydrogen atom as its side chain.
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Hemiaminal
A hemiaminal (also carbinolamine) is a functional group or type of chemical compound that has a hydroxyl group and an amine attached to the same carbon atom: -C(OH)(NR2)-.
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Lone pair
In chemistry, a lone pair refers to a pair of valence electrons that are not shared with another atomIUPAC Gold Book definition: and is sometimes called a non-bonding pair.
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Lysine
Lysine (symbol Lys or K) is an α-amino acid that is used in the biosynthesis of proteins.
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Malaria
Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.
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Methylene bridge
In organic chemistry, a methylene bridge, methylene spacer, or methanediyl group is any part of a molecule with formula --; namely, a carbon atom bound to two hydrogen atoms and connected by single bonds to two other distinct atoms in the rest of the molecule.
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Mitochondrion
The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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NMDA receptor
The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and ion channel protein found in nerve cells.
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Nucleophile
Nucleophile is a chemical species that donates an electron pair to an electrophile to form a chemical bond in relation to a reaction.
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Pemetrexed
Pemetrexed (brand name Alimta) is a chemotherapy drug manufactured and marketed by Eli Lilly and Company.
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Pharmacokinetics
Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.
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Plasmodium
Plasmodium is a genus of unicellular eukaryotes that are obligate parasites of vertebrates and insects.
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Prokaryote
A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.
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Proline
Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins.
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Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
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Protein subunit
In structural biology, a protein subunit is a single protein molecule that assembles (or "coassembles") with other protein molecules to form a protein complex.
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Proton
| magnetic_moment.
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Pyridoxal phosphate
Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic reactions.
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Schiff base
A Schiff base (named after Hugo Schiff) is a compound with the general structure R2C.
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Serine
Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins.
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Smith–Magenis syndrome
Smith–Magenis Syndrome (SMS) has features including intellectual disability, facial abnormalities, difficulty sleeping, and numerous behavioral problems such as self-harm.
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Spontaneous process
A spontaneous process is the time-evolution of a system in which it releases free energy and it moves to a lower, more thermodynamically stable energy state.
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Stacking (chemistry)
In chemistry, pi stacking (also called π–π stacking) refers to attractive, noncovalent interactions between aromatic rings, since they contain pi bonds.
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Substrate (chemistry)
In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.
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Tetrahydrofolic acid
Tetrahydrofolic acid, or tetrahydrofolate, is a folic acid derivative.
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Tetramer
A tetramer (tetra-, "four" + -mer, "parts") is an oligomer formed from four monomers or subunits.
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Threonine
Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.
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Tyrosine
Tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins.
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Vitamin B6
Vitamin B6 refers to a group of chemically similar compounds which can be interconverted in biological systems.
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10-Formyltetrahydrofolate
10-Formyltetrahydrofolate (10-CHO-THF) is a form of tetrahydrofolate that acts as a donor of formyl groups in anabolism.
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5,10-Methylenetetrahydrofolate
5,10-Methylenetetrahydrofolate (N5,N10-Methylenetetrahydrofolate; 5,10-CH2-THF) is the substrate used by the enzyme methylenetetrahydrofolate reductase (MTHFR) to generate 5-methyltetrahydrofolate (5-MTHF, or levomefolic acid).
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Redirects here:
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase, EC 2.1.2.1, Glycine hydroxymethyltransferase, SHMT, SHMT1, SHMT2.
References
[1] https://en.wikipedia.org/wiki/Serine_hydroxymethyltransferase