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Androstenediol

Index Androstenediol

Androstenediol, or 5-androstenediol (abbreviated as A5 or Δ5-diol), also known as androst-5-ene-3β,17β-diol, is an endogenous weak androgen and estrogen steroid hormone and intermediate in the biosynthesis of testosterone from dehydroepiandrosterone (DHEA). [1]

35 relations: Acute radiation syndrome, Adrenal cortex, Anabolic steroid, Androgen, Androstane, Androstenedione, Armed Forces Radiobiology Research Institute, Biological activity, Biosynthesis, Clinical trial, Dehydroepiandrosterone, Endogeny (biology), Estradiol, Estrogen, Estrogen receptor alpha, Estrogen receptor beta, Immune system, In vivo, Ionizing radiation, Ligand (biochemistry), Metabolite, Natural product, Oral administration, Placebo, Platelet, Rat, Reaction intermediate, Rhesus macaque, Steroid, Steroid hormone, Testosterone, United States Department of Health and Human Services, White blood cell, 3β-Androstanediol, 4-Androstenediol.

Acute radiation syndrome

Acute radiation syndrome (ARS) is a collection of health effects that are present within 24 hours of exposure to high doses of ionizing radiation.

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Adrenal cortex

Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, such as aldosterone and cortisol, respectively.

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Anabolic steroid

Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.

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Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

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Androstane

Androstane is a C19 steroid with a gonane core.

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Androstenedione

Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).

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Armed Forces Radiobiology Research Institute

The Armed Forces Radiobiology Research Institute (AFRRI) is a triservice laboratory in Bethesda, Maryland, USA, and was chartered by the U.S. Congress in 1961.

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Biological activity

In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter.

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Biosynthesis

Biosynthesis (also called anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Dehydroepiandrosterone

Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone.

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Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

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Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.

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Estrogen

Estrogen, or oestrogen, is the primary female sex hormone.

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Estrogen receptor alpha

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.

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Estrogen receptor beta

Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen.

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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In vivo

Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

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Ionizing radiation

Ionizing radiation (ionising radiation) is radiation that carries enough energy to liberate electrons from atoms or molecules, thereby ionizing them.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Natural product

A natural product is a chemical compound or substance produced by a living organism—that is, found in nature.

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Oral administration

| name.

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Placebo

A placebo is a substance or treatment of no intended therapeutic value.

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Platelet

Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.

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Rat

Rats are various medium-sized, long-tailed rodents in the superfamily Muroidea.

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Reaction intermediate

A reaction intermediate or an intermediate is a molecular entity that is formed from the reactants (or preceding intermediates) and reacts further to give the directly observed products of a chemical reaction.

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Rhesus macaque

The rhesus macaque (Macaca mulatta) is one of the best-known species of Old World monkeys.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Steroid hormone

A steroid hormone is a steroid that acts as a hormone.

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Testosterone

Testosterone is the primary male sex hormone and an anabolic steroid.

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United States Department of Health and Human Services

The United States Department of Health and Human Services (HHS), also known as the Health Department, is a cabinet-level department of the U.S. federal government with the goal of protecting the health of all Americans and providing essential human services.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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3β-Androstanediol

3β-Androstanediol, also known as 5α-androstane-3β,17β-diol, and often shortened to 3β-diol, is an endogenous steroid hormone.

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4-Androstenediol

4-Androstenediol, also known as androst-4-ene-3β,17β-diol, is an androstenediol that is converted to testosterone.

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Redirects here:

5-AED, 5-Androstene-3,17-diol, 5-Androstenediol, 5-androstenediol, HE 2100, HE-2100, HE2100, Hermaphrodiol, Neumune, Δ5-Androstenediol, Δ5-androstenediol.

References

[1] https://en.wikipedia.org/wiki/Androstenediol

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