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5-Carboxamidotryptamine

Index 5-Carboxamidotryptamine

5-Carboxamidotryptamine (5-CT) is a tryptamine derivative closely related to the neurotransmitter serotonin. [1]

24 relations: Acetryptine, Agonist, Alpha-Methylserotonin, British Journal of Pharmacology, Derivative (chemistry), Functional selectivity, Ligand (biochemistry), Neurotransmitter, Serotonin, Sumatriptan, Tryptamine, 2-Methyl-5-hydroxytryptamine, 5-Benzyloxytryptamine, 5-HT1A receptor, 5-HT1B receptor, 5-HT1D receptor, 5-HT1E receptor, 5-HT1F receptor, 5-HT2 receptor, 5-HT3 receptor, 5-HT5A receptor, 5-HT6 receptor, 5-HT7 receptor, 5-Methoxytryptamine.

Acetryptine

Acetryptine (INN) (developmental code name W-2965-A), also known as 5-acetyltryptamine (5-AT), is a drug described as an antihypertensive agent which was never marketed.

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Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Alpha-Methylserotonin

α-Methylserotonin (αMS), also known as α-methyl-5-hydroxytryptamine (α-methyl-5-HT) or 5-hydroxy-α-methyltryptamine (5-HO-αMT), is a tryptamine derivative closely related to the neurotransmitter serotonin (5-HT).

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British Journal of Pharmacology

The British Journal of Pharmacology is a biweekly peer-reviewed medical journal covering all aspects of experimental pharmacology.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Functional selectivity

Functional selectivity (or “agonist trafficking”, “biased agonism”, “biased signalling”, "ligand bias" and “differential engagement”) is the ligand-dependent selectivity for certain signal transduction pathways relative to a reference ligand (often the endogenous hormone or peptide) at the same receptor.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Sumatriptan

Sumatriptan is a medication used for the treatment of migraine and cluster headaches.

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Tryptamine

Tryptamine is a monoamine alkaloid.

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2-Methyl-5-hydroxytryptamine

2-Methyl-5-hydroxytryptamine (2-Methylserotonin, 2-Methyl-5-HT) is a tryptamine derivative closely related to the neurotransmitter serotonin which acts as a moderately selective full agonist at the 5-HT3 receptor.

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5-Benzyloxytryptamine

5-Benzyloxytryptamine (5-BT), is a tryptamine derivative which acts as an agonist at the 5-HT1D, 5-HT2 and 5-HT6 serotonin receptors.

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5-HT1A receptor

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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5-HT1B receptor

5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene.

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5-HT1D receptor

5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it.

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5-HT1E receptor

5-hydroxytryptamine (serotonin) 1E receptor (5-HT1E) is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family (Gi-coupled serotonin receptor).

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5-HT1F receptor

5-hydroxytryptamine (serotonin) receptor 1F, also known as HTR1F is a 5-HT1 receptor protein and also denotes the human gene encoding it.

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5-HT2 receptor

The 5-HT2 receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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5-HT3 receptor

The 5-HT3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin) receptors which are G protein-coupled receptors.

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5-HT5A receptor

5-Hydroxytryptamine (serotonin) receptor 5A, also known as HTR5A, is a protein that in humans is encoded by the HTR5A gene.

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5-HT6 receptor

The 5HT6 receptor is a subtype of 5HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5HT).

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5-HT7 receptor

The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) The 5-HT7 receptor is coupled to Gs (stimulates the production of the intracellular signaling molecule cAMP) and is expressed in a variety of human tissues, particularly in the brain, the gastrointestinal tract, and in various blood vessels.

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5-Methoxytryptamine

5-Methoxytryptamine (5-MT), also known as mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin.

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Redirects here:

5-CT, Carboxamidotryptamine.

References

[1] https://en.wikipedia.org/wiki/5-Carboxamidotryptamine

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