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Index 5-Ethyl-DMT

5-Ethyl-N,N-dimethyltryptamine is a tryptamine derivative which acts as an agonist at the 5-HT1A and 5-HT1D serotonin receptors, with around 3x selectivity for 5-HT1D. [1]

12 relations: Agonist, Derivative (chemistry), Receptor (biochemistry), Serotonin, Sumatriptan, Tryptamine, 5,N,N-TMT, 5-Benzyloxytryptamine, 5-Carboxamidotryptamine, 5-Ethoxy-DMT, 5-HT1A receptor, 5-HT1D receptor.


An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Sumatriptan is a medication used for the treatment of migraine and cluster headaches.

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Tryptamine is a monoamine alkaloid.

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5,N,N-trimethyltryptamine (5,N,N-TMT; 5-TMT) is a tryptamine derivative that is a psychedelic drug.

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5-Benzyloxytryptamine (5-BT), is a tryptamine derivative which acts as an agonist at the 5-HT1D, 5-HT2 and 5-HT6 serotonin receptors.

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5-Carboxamidotryptamine (5-CT) is a tryptamine derivative closely related to the neurotransmitter serotonin.

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5-Ethoxy-DMT (5-ethoxy-N,N-dimethyltryptamine, 5-EtO-DMT, O-ethylbufotenine) is a tryptamine derivative which has been previously synthesized as a chemical intermediate, but has not been studied to determine its pharmacology.

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5-HT1A receptor

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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5-HT1D receptor

5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it.

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[1] https://en.wikipedia.org/wiki/5-Ethyl-DMT

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