Table of Contents
241 relations: A-372159, Acetylcholine, Adrenaline, Adrenergic receptor, Adrenocorticotropic hormone, Agomelatine, Agonist, AL-38022A, Almotriptan, Alosetron, Alprenolol, Amitriptyline, Analgesic, Anorectic, Antidepressant, Antiemetic, Antihypertensive drug, Antimigraine drug, Antipsychotic, Anxiety, Anxiolytic, Appetite stimulant, AR-A000002, Aripiprazole, AS-19 (drug), Asenapine, Atypical antipsychotic, Autoreceptor, Benzylpiperazine, BIMU8, Blood vessel, BMY-7378, BRL-15,572, BRL-54443, Bryan Roth, Bufotenin, Buspirone, BW-723C86, Caenorhabditis elegans, Cell membrane, Central nervous system, CGS-12066A, Cinitapride, Cisapride, Clomipramine, Cloning, Clozapine, Cognition, Cortisol, CP-135807, ... Expand index (191 more) »
- Serotonin receptors
A-372159
A-372159 is a drug which acts as a potent and selective partial agonist for the 5HT2C receptor, with more than 100x selectivity over the closely related 5-HT2B receptor and a Ki of 3nM.
See 5-HT receptor and A-372159
Acetylcholine
Acetylcholine (ACh) is an organic compound that functions in the brain and body of many types of animals (including humans) as a neurotransmitter.
See 5-HT receptor and Acetylcholine
Adrenaline
Adrenaline, also known as epinephrine, is a hormone and medication which is involved in regulating visceral functions (e.g., respiration).
See 5-HT receptor and Adrenaline
Adrenergic receptor
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β2) agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example.
See 5-HT receptor and Adrenergic receptor
Adrenocorticotropic hormone
Adrenocorticotropic hormone (ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland.
See 5-HT receptor and Adrenocorticotropic hormone
Agomelatine
Agomelatine, sold under the brand names Valdoxan and Thymanax, among others, is an atypical antidepressant most commonly used to treat major depressive disorder and generalized anxiety disorder.
See 5-HT receptor and Agomelatine
Agonist
An agonist is a chemical that activates a receptor to produce a biological response.
AL-38022A
AL-38022A is an indazole derivative drug which is one of a range of similar drugs developed for scientific research and with some possible clinical applications.
See 5-HT receptor and AL-38022A
Almotriptan
Almotriptan (trade name Axert and others) is a triptan medication discovered and developed by Almirall for the treatment of heavy migraine headache.
See 5-HT receptor and Almotriptan
Alosetron
Alosetron, sold under the brand name Lotronex among others, is a 5-HT3 antagonist used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in females only.
See 5-HT receptor and Alosetron
Alprenolol
Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as a 5-HT1A and 5-HT1B receptor antagonist, used in the treatment of angina pectoris.
See 5-HT receptor and Alprenolol
Amitriptyline
Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches.
See 5-HT receptor and Amitriptyline
Analgesic
An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.
See 5-HT receptor and Analgesic
Anorectic
An anorectic or anorexic is a drug which reduces appetite, resulting in lower food consumption, leading to weight loss.
See 5-HT receptor and Anorectic
Antidepressant
Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction.
See 5-HT receptor and Antidepressant
Antiemetic
An antiemetic is a drug that is effective against vomiting and nausea.
See 5-HT receptor and Antiemetic
Antihypertensive drug
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure).
See 5-HT receptor and Antihypertensive drug
Antimigraine drug
Antimigraine drugs are medications intended to reduce the effects or intensity of migraine headache.
See 5-HT receptor and Antimigraine drug
Antipsychotic
Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders.
See 5-HT receptor and Antipsychotic
Anxiety
Anxiety is an emotion which is characterised by an unpleasant state of inner turmoil and includes feelings of dread over anticipated events.
Anxiolytic
An anxiolytic (also antipanic or anti-anxiety agent) is a medication or other intervention that reduces anxiety.
See 5-HT receptor and Anxiolytic
Appetite stimulant
An orexigenic, or appetite stimulant, is a drug, hormone, or compound that increases appetite and may induce hyperphagia.
See 5-HT receptor and Appetite stimulant
AR-A000002
AR-A000002 is a drug which is one of the first compounds developed to act as a selective antagonist for the serotonin receptor 5-HT1B, with approximately 10x selectivity for 5-HT1B over the closely related 5-HT1D receptor.
See 5-HT receptor and AR-A000002
Aripiprazole
Aripiprazole, sold under the brand names Abilify and Aristada, among others, is an atypical antipsychotic. It is primarily used in the treatment of schizophrenia and bipolar disorder; other uses include as an add-on treatment in major depressive disorder and obsessive compulsive disorder (OCD), tic disorders, and irritability associated with autism.
See 5-HT receptor and Aripiprazole
AS-19 (drug)
AS-19 is a substance which acts as a potent agonist at the 5-HT7 receptor, with an IC50 of 0.83 nM.
See 5-HT receptor and AS-19 (drug)
Asenapine
Asenapine, sold under the brand name Saphris among others, is an atypical antipsychotic medication used to treat schizophrenia and acute mania associated with bipolar disorder as well as the medium to long-term management of bipolar disorder.
See 5-HT receptor and Asenapine
Atypical antipsychotic
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric conditions.
See 5-HT receptor and Atypical antipsychotic
Autoreceptor
An autoreceptor is a type of receptor located in the membranes of nerve cells.
See 5-HT receptor and Autoreceptor
Benzylpiperazine
Benzylpiperazine (BZP) is a substance often used as a recreational drug and is known to have euphoriant and stimulant properties.
See 5-HT receptor and Benzylpiperazine
BIMU8
BIMU-8 is a drug which acts as a 5-HT4 receptor selective agonist.
Blood vessel
Blood vessels are the structures of the circulatory system that transport blood throughout the human body.
See 5-HT receptor and Blood vessel
BMY-7378
BMY-7,378 is a 5-HT1A receptor weak partial agonist/antagonist and α1D-adrenergic receptor antagonist.
See 5-HT receptor and BMY-7378
BRL-15,572
BRL-15,572 is a drug which acts as a selective antagonist for the serotonin receptor subtype 5-HT1D, with around 60x selectivity over other related receptors.
See 5-HT receptor and BRL-15,572
BRL-54443
BRL-54443 is a drug which acts as a selective agonist for the 5-HT1E and 5-HT1F serotonin receptor subtypes.
See 5-HT receptor and BRL-54443
Bryan Roth
Bryan L. Roth is the Michael Hooker Distinguished Professor of Protein Therapeutics and Translational Proteomics, UNC School of Medicine.
See 5-HT receptor and Bryan Roth
Bufotenin
Bufotenin (5-HO-DMT, bufotenine, dimethylserotonin) is a tryptamine derivative, more specifically, a DMT analog, related to the neurotransmitter serotonin.
See 5-HT receptor and Bufotenin
Buspirone
Buspirone, sold under the brand name Buspar, among others, is an anxiolytic, a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder.
See 5-HT receptor and Buspirone
BW-723C86
BW-723C86 is a tryptamine derivative drug which acts as a 5-HT2B receptor agonist.
See 5-HT receptor and BW-723C86
Caenorhabditis elegans
Caenorhabditis elegans is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments.
See 5-HT receptor and Caenorhabditis elegans
Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space).
See 5-HT receptor and Cell membrane
Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord.
See 5-HT receptor and Central nervous system
CGS-12066A
CGS-12066A is a drug which acts as a potent and selective agonist for the 5-HT1B receptor with lower affinity for the three 5-HT2 receptor subtypes.
See 5-HT receptor and CGS-12066A
Cinitapride
Cinitapride (trade names Cintapro, Pemix) is a gastroprokinetic agent and antiemetic agent of the benzamide class which is marketed in India, Mexico, Pakistan and Spain.
See 5-HT receptor and Cinitapride
Cisapride
Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract.
See 5-HT receptor and Cisapride
Clomipramine
Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA).
See 5-HT receptor and Clomipramine
Cloning
Cloning is the process of producing individual organisms with identical genomes, either by natural or artificial means.
Clozapine
Clozapine is a psychiatric medication and was the first atypical antipsychotic (also called second-generation antipsychotic) to be discovered.
See 5-HT receptor and Clozapine
Cognition
Cognition is the "mental action or process of acquiring knowledge and understanding through thought, experience, and the senses".
See 5-HT receptor and Cognition
Cortisol
Cortisol is a steroid hormone in the glucocorticoid class of hormones and a stress hormone.
See 5-HT receptor and Cortisol
CP-135807
CP-135807 is a drug which acts as a potent and selective agonist for the 5-HT1D serotonin receptor, and is used to study the function of this receptor subtype.
See 5-HT receptor and CP-135807
CP-93129
CP-93129 is a drug which acts as a potent and selective serotonin 5-HT1B receptor agonist, with approximately 150x and 200x selectivity over the closely related 5-HT1D and 5-HT1A receptors.
See 5-HT receptor and CP-93129
CP-94253
CP-94253 is a drug which acts as a potent and selective serotonin 5-HT1B receptor agonist, with approximately 25× and 40× selectivity over the closely related 5-HT1D and 5-HT1A receptors.
See 5-HT receptor and CP-94253
Cyanopindolol
Cyanopindolol is a drug related to pindolol which acts as both a β1 adrenoceptor antagonist and a 5-HT1A receptor antagonist.
See 5-HT receptor and Cyanopindolol
Cyclic adenosine monophosphate
Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger, or cellular signal occurring within cells, that is important in many biological processes.
See 5-HT receptor and Cyclic adenosine monophosphate
Cyproheptadine
Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties.
See 5-HT receptor and Cyproheptadine
Dazopride
Dazopride (AHR-5531) is an antiemetic and gastroprokinetic agent of the benzamide class which was never marketed.
See 5-HT receptor and Dazopride
Depolarization
In biology, depolarization or hypopolarization is a change within a cell, during which the cell undergoes a shift in electric charge distribution, resulting in less negative charge inside the cell compared to the outside.
See 5-HT receptor and Depolarization
Diglyceride
A diglyceride, or diacylglycerol (DAG), is a glyceride consisting of two fatty acid chains covalently bonded to a glycerol molecule through ester linkages.
See 5-HT receptor and Diglyceride
Dihydroergotamine
Dihydroergotamine (DHE), sold under the brand names D.H.E. 45 and Migranal among others, is an ergot alkaloid used to treat migraines.
See 5-HT receptor and Dihydroergotamine
Dolasetron
Dolasetron (trade name Anzemet) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.
See 5-HT receptor and Dolasetron
Dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells.
See 5-HT receptor and Dopamine
Doxepin
Doxepin is a medication belonging to the tricyclic antidepressant (TCA) class of drugs used to treat major depressive disorder, anxiety disorders, chronic hives, and insomnia.
E-55888
E-55888 is a drug developed by Esteve, which acts as a potent and selective full agonist at the 5HT7 serotonin receptor, and is used for investigating the role of 5-HT7 receptors in the perception of pain.
E-6837
E-6837 is an orally active, 5-HT6 agonist developed in an attempt to create an anti-obesity medication.
EGIS-12,233
EGIS-12,233 is a drug with applications in scientific research, acting as a potent and selective antagonist for both the 5-HT6 and 5-HT7 serotonin receptor subtypes, with good selectivity over other receptors.
See 5-HT receptor and EGIS-12,233
Eletriptan
Eletriptan, sold under the brand name Relpax and used in the form of eletriptan hydrobromide, is a second-generation triptan medication intended for treatment of migraine headaches.
See 5-HT receptor and Eletriptan
Eltoprazine
Eltoprazine (developmental code name DU-28,853) is a serotonergic drug of the phenylpiperazine class which is described as a serenic or antiaggressive agent.
See 5-HT receptor and Eltoprazine
EMD-386088
EMD-386088 is an indole derivative which is used in scientific research.
See 5-HT receptor and EMD-386088
EMDT
2-Ethyl-5-methoxy-N,N-dimethyltryptamine (EMDT) is a tryptamine derivative which is used in scientific research.
Empathogen
Empathogens or entactogens are a class of psychoactive drugs that induce the production of experiences of emotional communion, oneness, relatedness, emotional openness—that is, empathy or sympathy—as particularly observed and reported for experiences with 3,4-methylenedioxymethamphetamine (MDMA).
See 5-HT receptor and Empathogen
Eplivanserin
Eplivanserin (SR-46,349; planned trade name Ciltyri) was an experimental drug for the treatment of insomnia which was being developed by Sanofi Aventis.
See 5-HT receptor and Eplivanserin
Ergometrine
Ergometrine, also known as ergonovine and sold under the brand names Ergotrate, Ergostat, and Syntometrine among others, is a medication used to cause contractions of the uterus to treat heavy vaginal bleeding after childbirth.
See 5-HT receptor and Ergometrine
Ergotamine
Ergotamine, sold under the brand name Ergomar among others, is an ergopeptine and part of the ergot family of alkaloids; it is structurally and biochemically closely related to ergoline.
See 5-HT receptor and Ergotamine
Etoperidone
Etoperidone, associated with several brand names, is an atypical antidepressant which was developed in the 1970s and either is no longer marketed or was never marketed.
See 5-HT receptor and Etoperidone
F-15,599
F-15,599, also known as NLX-101, is a potent and selective 5-HT1A receptor full agonist.
See 5-HT receptor and F-15,599
Fenfluramine
Fenfluramine, sold under the brand name Fintepla, is a serotonergic medication used for the treatment of seizures associated with Dravet syndrome and Lennox–Gastaut syndrome.
See 5-HT receptor and Fenfluramine
Flesinoxan
Flesinoxan (DU-29,373) is a potent and selective 5-HT1A receptor partial/near-full agonist of the phenylpiperazine class.
See 5-HT receptor and Flesinoxan
Fluoxetine
Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
See 5-HT receptor and Fluoxetine
Frovatriptan
Frovatriptan, sold under the brand name Frova, is a triptan drug developed by Vernalis for the treatment of migraine headaches and for short term prevention of menstrual migraine.
See 5-HT receptor and Frovatriptan
G protein-coupled receptor
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses.
See 5-HT receptor and G protein-coupled receptor
GABA
GABA (gamma Aminobutyric acid, γ-Aminobutyric acid) is the chief inhibitory neurotransmitter in the developmentally mature mammalian central nervous system.
Gastrointestinal tract
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines.
See 5-HT receptor and Gastrointestinal tract
Gepirone
Gepirone, sold under the brand name Exxua, is a medication used for the treatment of major depressive disorder.
See 5-HT receptor and Gepirone
Gi alpha subunit
Gi protein alpha subunit is a family of heterotrimeric G protein alpha subunits.
See 5-HT receptor and Gi alpha subunit
Glossary of biology
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.
See 5-HT receptor and Glossary of biology
Glutamic acid
Glutamic acid (symbol Glu or E; the anionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins.
See 5-HT receptor and Glutamic acid
Gq alpha subunit
Gq protein alpha subunit is a family of heterotrimeric G protein alpha subunits.
See 5-HT receptor and Gq alpha subunit
GR-127935
GR-127935 is a drug which acts as a selective antagonist at the serotonin receptors 5-HT1B and 5-HT1D.
See 5-HT receptor and GR-127935
Granisetron
Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy and radiotherapy.
See 5-HT receptor and Granisetron
Gs alpha subunit
The Gs alpha subunit (Gαs, Gsα) is a subunit of the heterotrimeric G protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase.
See 5-HT receptor and Gs alpha subunit
Hallucinogen
Hallucinogens are a large and diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes.
See 5-HT receptor and Hallucinogen
Haloperidol
Haloperidol, sold under the brand name Haldol among others, is a typical antipsychotic medication.
See 5-HT receptor and Haloperidol
Heteroreceptor
A heteroreceptor is a receptor regulating the synthesis and/or the release of mediators other than its own ligand.
See 5-HT receptor and Heteroreceptor
Hydroxyzine
Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication.
See 5-HT receptor and Hydroxyzine
Hypnotic
Hypnotic (from Greek Hypnos, sleep), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep (or surgical anesthesiaWhen used in anesthesia to produce and maintain unconsciousness, "sleep" is metaphorical as there are no regular sleep stages or cyclical natural states; patients rarely recover from anesthesia feeling refreshed and with renewed energy.
See 5-HT receptor and Hypnotic
Iloperidone
Iloperidone, commonly known as Fanapt and previously known as Zomaril, is an atypical antipsychotic for the treatment of schizophrenia.
See 5-HT receptor and Iloperidone
Imipramine
Imipramine, sold under the brand name Tofranil, among others, is a tricyclic antidepressant (TCA) mainly used in the treatment of depression.
See 5-HT receptor and Imipramine
Inositol trisphosphate
Inositol trisphosphate or inositol 1,4,5-trisphosphate abbreviated InsP3 or Ins3P or IP3 is an inositol phosphate signaling molecule.
See 5-HT receptor and Inositol trisphosphate
Iodocyanopindolol
Iodocyanopindolol (INN) is a drug related to pindolol which acts as both a β1 adrenoreceptor antagonist and a 5-HT1A receptor antagonist.
See 5-HT receptor and Iodocyanopindolol
Ion channel
Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore.
See 5-HT receptor and Ion channel
Ipsapirone
Ipsapirone is a selective 5-HT1A receptor partial agonist of the piperazine and azapirone chemical classes.
See 5-HT receptor and Ipsapirone
Isamoltane
Isamoltane (CGP-361A) is a drug used in scientific research.
See 5-HT receptor and Isamoltane
Ketanserin
Ketanserin (INN, USAN, BAN) (brand name Sufrexal; former developmental code name R41468) is a drug used clinically as an antihypertensive agent and in scientific research to study the serotonergic system; specifically, the 5-HT2 receptor family. It was discovered at Janssen Pharmaceutica in 1980. It is not available in the United States.
See 5-HT receptor and Ketanserin
Lasmiditan
Lasmiditan, sold under the brand name Reyvow, is a medication used for the acute (active but short-term) treatment of migraine with or without aura (a sensory phenomenon or visual disturbance) in adults.
See 5-HT receptor and Lasmiditan
Latrepirdine
Latrepirdine (INN, also known as dimebolin and sold as Dimebon) is an antihistamine drug which has been used clinically in Russia since 1983.
See 5-HT receptor and Latrepirdine
Lecozotan
Lecozotan is an investigational drug by Wyeth tested for improvement of cognitive functions of Alzheimer's disease patients.
See 5-HT receptor and Lecozotan
Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
See 5-HT receptor and Ligand (biochemistry)
Ligand-gated ion channel
Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na+, K+, Ca2+, and/or Cl− to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.
See 5-HT receptor and Ligand-gated ion channel
Lisuride
Lisuride, sold under the brand name Dopergin among others, is a monoaminergic medication of the ergoline class which is used in the treatment of Parkinson's disease, migraine, and high prolactin levels.
See 5-HT receptor and Lisuride
Lorcaserin
Lorcaserin, marketed under the brand name Belviq, was a weight-loss drug developed by Arena Pharmaceuticals.
See 5-HT receptor and Lorcaserin
LSD
Lysergic acid diethylamide, commonly known as LSD (from German Lysergsäure-diethylamid), and known colloquially as acid or lucy, is a potent psychedelic drug.
LY-334370
LY-334370 is a selective 5-HT1F receptor agonist which was under development by Eli Lilly and Company for the treatment of migraine headaches.
See 5-HT receptor and LY-334370
Lysine
Lysine (symbol Lys or K) is an α-amino acid that is a precursor to many proteins.
MDMA
3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (tablet form), and molly or mandy (crystal form), is a potent empathogen–entactogen with stimulant and minor psychedelic properties.
Mefway (18F)
Mefway is a serotonin 5-HT1A receptor antagonist used in medical research, usually in the form of mefway (18F) as a positron emission tomography (PET) radiotracer.
See 5-HT receptor and Mefway (18F)
Memantine
Memantine, sold under the brand name Axura among others, is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. It is taken by mouth. Common side effects include headache, constipation, sleepiness, and dizziness. Severe side effects may include blood clots, psychosis, and heart failure.
See 5-HT receptor and Memantine
Mescaline
Mescaline or mescalin (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin.
See 5-HT receptor and Mescaline
Metergoline
Metergoline, also known as methergoline and sold under the brand names Contralac (veterinary) and Liserdol (clinical), is a monoaminergic medication of the ergoline group which is used as a prolactin inhibitor in the treatment of hyperprolactinemia (high prolactin levels) and to suppress lactation.
See 5-HT receptor and Metergoline
Methylergometrine
Methylergometrine, also known as methylergonovine and sold under the brand name Methergine, is a medication of the ergoline and lysergamide groups which is used as an oxytocic in obstetrics and in the treatment of migraine.
See 5-HT receptor and Methylergometrine
Methylphenidate
Methylphenidate, sold under the brand names Ritalin and Concerta among others, is a potent central nervous system (CNS) stimulant used medically to treat attention deficit hyperactivity disorder (ADHD) and, to a lesser extent, narcolepsy.
See 5-HT receptor and Methylphenidate
Methysergide
Methysergide, sold under the brand names Deseril and Sansert, is a monoaminergic medication of the ergoline and lysergamide groups which is used in the prophylaxis and treatment of migraine and cluster headaches.
See 5-HT receptor and Methysergide
Metitepine
Metitepine (developmental code names Ro 8-6837 (maleate), VUFB-6276 (mesylate)), also known as methiothepin, is a drug described as a "psychotropic agent" of the tricyclic group which was never marketed.
See 5-HT receptor and Metitepine
Metoclopramide
Metoclopramide is a medication used for stomach and esophageal problems.
See 5-HT receptor and Metoclopramide
Mianserin
Mianserin, sold under the brand name Tolvon among others, is an atypical antidepressant that is used primarily in the treatment of depression in Europe and elsewhere in the world.
See 5-HT receptor and Mianserin
Migraine
Migraine is a genetically influenced complex neurological disorder characterized by episodes of moderate-to-severe headache, most often unilateral and generally associated with nausea and light and sound sensitivity.
See 5-HT receptor and Migraine
Mirtazapine
Mirtazapine, sold under the brand name Remeron among others, is an atypical tetracyclic antidepressant, and as such is used primarily to treat depression.
See 5-HT receptor and Mirtazapine
Mood (psychology)
In psychology, a mood is an affective state.
See 5-HT receptor and Mood (psychology)
Mosapride
Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
See 5-HT receptor and Mosapride
MS-245
MS-245 is a tryptamine derivative used in scientific research.
NAN-190
NAN-190 is a drug and research chemical widely used in scientific studies.
Naratriptan
Naratriptan (trade names include Amerge) is a triptan drug marketed by GlaxoSmithKline and is used for the treatment of migraine headaches.
See 5-HT receptor and Naratriptan
Nebivolol
Nebivolol is a beta blocker used to treat high blood pressure and heart failure.
See 5-HT receptor and Nebivolol
Nefazodone
Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant medication which is used in the treatment of depression and for other uses.
See 5-HT receptor and Nefazodone
Nematode
The nematodes (or; Νηματώδη; Nematoda), roundworms or eelworms constitute the phylum Nematoda.
See 5-HT receptor and Nematode
Neurotransmission
Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and react with the receptors on the dendrites of another neuron (the postsynaptic neuron) a short distance away.
See 5-HT receptor and Neurotransmission
Neurotransmitter
A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse.
See 5-HT receptor and Neurotransmitter
Nootropic
Nootropics (or; but not or, which are common mispronunciations), colloquially brain supplements, smart drugs and cognitive enhancers, are natural, semisynthetic or synthetic compounds which purportedly improve cognitive functions, such as executive functions, attention or memory.
See 5-HT receptor and Nootropic
Noradrenergic and specific serotonergic antidepressant
Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants.
See 5-HT receptor and Noradrenergic and specific serotonergic antidepressant
Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone, neurotransmitter and neuromodulator.
See 5-HT receptor and Norepinephrine
Norfenfluramine
Norfenfluramine, or 3-trifluoromethylamphetamine, is a never-marketed drug of the amphetamine family that behaves as a serotonin and norepinephrine releasing agent and potent 5-HT2A, 5-HT2B, and 5-HT2C agonist.
See 5-HT receptor and Norfenfluramine
Olanzapine
Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder.
See 5-HT receptor and Olanzapine
Ondansetron
Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, migraines or surgery.
See 5-HT receptor and Ondansetron
Oxprenolol
Oxprenolol (brand names Trasacor, Trasicor, Coretal, Laracor, Slow-Pren, Captol, Corbeton, Slow-Trasicor, Tevacor, Trasitensin, Trasidex) is a non-selective beta blocker with some intrinsic sympathomimetic activity.
See 5-HT receptor and Oxprenolol
Oxytocin
Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary.
See 5-HT receptor and Oxytocin
Paroxetine
Paroxetine, sold under the brand names Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, post-traumatic stress disorder, generalized anxiety disorder, and premenstrual dysphoric disorder.
See 5-HT receptor and Paroxetine
Partial agonist
In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.
See 5-HT receptor and Partial agonist
Peripheral nervous system
The peripheral nervous system (PNS) is one of two components that make up the nervous system of bilateral animals, with the other part being the central nervous system (CNS).
See 5-HT receptor and Peripheral nervous system
Piboserod
Piboserod is a selective 5-HT4 receptor antagonist which was marketed and manufactured by GlaxoSmithKline (GSK) under the trade name Serlipet for the management of atrial fibrillation and irritable bowel syndrome.
See 5-HT receptor and Piboserod
Pieris rapae
Pieris rapae is a small- to medium-sized butterfly species of the whites-and-yellows family Pieridae.
See 5-HT receptor and Pieris rapae
Pimavanserin
Pimavanserin, sold under the brand name Nuplazid, is an atypical antipsychotic which is approved for the treatment of Parkinson's disease psychosis and is also being studied for the treatment of Alzheimer's disease psychosis, schizophrenia, agitation, and major depressive disorder.
See 5-HT receptor and Pimavanserin
Pindolol
Pindolol, sold under the brand name Visken among others, is a nonselective beta blocker which is used in the treatment of hypertension.
See 5-HT receptor and Pindolol
Pizotifen
Pizotifen (INN) or pizotyline (USAN), trade name Sandomigran, is a benzocycloheptene-based drug used as a medicine, primarily as a preventive to reduce the frequency of recurrent migraine headaches.
See 5-HT receptor and Pizotifen
Platelet
Platelets or thrombocytes are a blood component whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
See 5-HT receptor and Platelet
PNU-22394
PNU-22394 is a drug which acts as an agonist at serotonin 5-HT2 receptors, with strongest binding affinity for 5-HT2A and 5-HT2C and slightly weaker at 5-HT2B, although it is only a full agonist at 5-HT2C, but partial agonist at 5-HT2A and 5-HT2B.
See 5-HT receptor and PNU-22394
Potassium
Potassium is a chemical element; it has symbol K (from Neo-Latin kalium) and atomic number19.
See 5-HT receptor and Potassium
Prokinetic agent
A prokinetic agent (also prokineticin, gastroprokinetic agent, gastrokinetic agent or propulsive) is a type of small peptide drug which enhances gastrointestinal motility by increasing the frequency or strength of contractions, but without disrupting their rhythm.
See 5-HT receptor and Prokinetic agent
Prolactin
Prolactin (PRL), also known as lactotropin and mammotropin, is a protein best known for its role in enabling mammals to produce milk.
See 5-HT receptor and Prolactin
Propranolol
Propranolol, sold under the brand name Inderal among others, is a medication of the beta blocker class. It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors, as well to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks.
See 5-HT receptor and Propranolol
Protein Data Bank
The Protein Data Bank (PDB) is a database for the three-dimensional structural data of large biological molecules such as proteins and nucleic acids, which is overseen by the Worldwide Protein Data Bank (wwPDB).
See 5-HT receptor and Protein Data Bank
Prucalopride
Prucalopride, sold under brand names Resolor and Motegrity among others, is a medication acting as a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalizing bowel movements.
See 5-HT receptor and Prucalopride
Pseudogene
Pseudogenes are nonfunctional segments of DNA that resemble functional genes.
See 5-HT receptor and Pseudogene
Psilocin
Psilocin (also known as 4-HO-DMT, 4-hydroxy DMT, psilocine, psilocyn, or psilotsin) is a substituted tryptamine alkaloid and a serotonergic psychedelic substance.
See 5-HT receptor and Psilocin
Psilocybin
Psilocybin is a naturally occurring psychedelic prodrug compound produced by more than 200 species of fungi.
See 5-HT receptor and Psilocybin
Psychedelic drug
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness".
See 5-HT receptor and Psychedelic drug
Quetiapine
Quetiapine, sold under the brand name Seroquel among others, is an atypical antipsychotic medication used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.
See 5-HT receptor and Quetiapine
Quipazine
Quipazine is a serotonergic drug of the piperazine group which is used in scientific research.
See 5-HT receptor and Quipazine
Rauwolscine
Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauvolfia and Corynanthe (including Pausinystalia).
See 5-HT receptor and Rauwolscine
Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
See 5-HT receptor and Receptor antagonist
Renzapride
Renzapride is a prokinetic agent and antiemetic which acts as a full 5-HT4 agonist and partial 5-HT3 antagonist.
See 5-HT receptor and Renzapride
Risperidone
Risperidone, sold under the brand name Risperdal among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder.
See 5-HT receptor and Risperidone
Ritanserin
Ritanserin, also known by its developmental code name R-55667, is a serotonin antagonist medication described as an anxiolytic, antidepressant, antiparkinsonian agent, and antihypertensive agent.
See 5-HT receptor and Ritanserin
Rizatriptan
Rizatriptan, sold under the brand name Maxalt among others, is a medication used for the treatment of migraine headaches.
See 5-HT receptor and Rizatriptan
Ro 04-6790
Ro 04-6790 is a drug, developed by Hoffmann–La Roche, which has applications in scientific research.
See 5-HT receptor and Ro 04-6790
Ro60-0175
Ro60-0175 is a drug developed by Hoffmann–La Roche, which has applications in scientific research.
See 5-HT receptor and Ro60-0175
RS-127445
RS-127445 is a drug which acts as a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 1000 times selectivity over the closely related 5-HT2A and 5-HT2C receptors.
See 5-HT receptor and RS-127445
RS-56812
RS-56812 is a potent and selective partial agonist at the 5HT3 receptor.
See 5-HT receptor and RS-56812
RS-67,333
RS-67,333 is a drug which has been investigated as a potential rapid-acting antidepressant, nootropic, and treatment for Alzheimer's disease.
See 5-HT receptor and RS-67,333
RU-24,969
RU-24,969 is a chemical compound widely used in scientific studies.
See 5-HT receptor and RU-24,969
SB-216641
SB-216641 is a drug which is a selective antagonist for the serotonin receptor 5-HT1B, with around 25x selectivity over the closely related 5-HT1D receptor.
See 5-HT receptor and SB-216641
SB-242084
SB-242084 is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor.
See 5-HT receptor and SB-242084
SB-258585
SB-258585 is a drug which is used in scientific research.
See 5-HT receptor and SB-258585
SB-269970
SB-269970 is a drug and research chemical developed by GlaxoSmithKline used in scientific studies.
See 5-HT receptor and SB-269970
SB-271046
SB-271046 is a drug which is used in scientific research.
See 5-HT receptor and SB-271046
SB-357134
SB-357134 is a drug which is used in scientific research.
See 5-HT receptor and SB-357134
SB-399885
SB-399885 is a drug which is used in scientific research.
See 5-HT receptor and SB-399885
SB-699551
SB-699551 is a drug which was the first compound developed to act as a selective antagonist for the serotonin receptor 5-HT5A, with selectivity of around 100x over other serotonin receptor subtypes.
See 5-HT receptor and SB-699551
Second messenger system
Second messengers are intracellular signaling molecules released by the cell in response to exposure to extracellular signaling molecules—the first messengers.
See 5-HT receptor and Second messenger system
Serotonin
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
See 5-HT receptor and Serotonin
Serotonin antagonist and reuptake inhibitor
Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics.
See 5-HT receptor and Serotonin antagonist and reuptake inhibitor
Serotonin syndrome
Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs.
See 5-HT receptor and Serotonin syndrome
Smooth muscle
Smooth (soft) muscle is one of the three major types of vertebrate muscle tissue, the other being skeletal and cardiac muscle.
See 5-HT receptor and Smooth muscle
Sodium
Sodium is a chemical element; it has symbol Na (from Neo-Latin natrium) and atomic number 11.
Substance P
Substance P (SP) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) and a type of neuropeptide, belonging to the tachykinin family of neuropeptides. It acts as a neurotransmitter and a neuromodulator. Substance P and the closely related neurokinin A (NKA) are produced from a polyprotein precursor after alternative splicing of the preprotachykinin A gene.
See 5-HT receptor and Substance P
Sumatriptan
Sumatriptan, sold under the brand name Imitrex among others, is a medication used to treat migraine headaches and cluster headaches.
See 5-HT receptor and Sumatriptan
Tandospirone
Tandospirone, sold under the brand name Sediel, is an anxiolytic and antidepressant medication used in Japan and China, where it is marketed by Dainippon Sumitomo Pharma.
See 5-HT receptor and Tandospirone
Tegaserod
Tegaserod is a 5-HT4 agonist manufactured by Novartis and sold under the names Zelnorm and Zelmac for the management of irritable bowel syndrome and constipation.
See 5-HT receptor and Tegaserod
Thermoregulation
Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different.
See 5-HT receptor and Thermoregulation
Tramadol
Tramadol, sold under the brand name Ultram among others, is an opioid pain medication and a serotonin–norepinephrine reuptake inhibitor (SNRI) used to treat moderately severe pain.
See 5-HT receptor and Tramadol
Trazodone
Trazodone, sold under many brand names, is an antidepressant medication.
See 5-HT receptor and Trazodone
Trifluoromethylphenylpiperazine
3-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the phenylpiperazine chemical class and is a substituted piperazine.
See 5-HT receptor and Trifluoromethylphenylpiperazine
Triptan
Triptans are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches.
Tropisetron
Tropisetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia.
See 5-HT receptor and Tropisetron
Valerenic acid
Valerenic acid is a sesquiterpenoid constituent of the essential oil of the valerian plant.
See 5-HT receptor and Valerenic acid
Vasopressin
Human vasopressin, also called antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, is a hormone synthesized from the AVP gene as a peptide prohormone in neurons in the hypothalamus, and is converted to AVP.
See 5-HT receptor and Vasopressin
Vilazodone
Vilazodone, sold under the brand name Viibryd among others, is a medication used to treat major depressive disorder.
See 5-HT receptor and Vilazodone
Vortioxetine
Vortioxetine, sold under the brand name Brintellix among others, is an antidepressant of the serotonin modulator and stimulator (SMS) class.
See 5-HT receptor and Vortioxetine
WAY-100135
WAY-100135 is a serotonergic drug of the phenylpiperazine family which is used in scientific research.
See 5-HT receptor and WAY-100135
WAY-100635
WAY-100635 is a piperazine drug and research chemical widely used in scientific studies.
See 5-HT receptor and WAY-100635
WAY-181187
WAY-181187 is a high affinity and selective 5-HT6 receptor full agonist.
See 5-HT receptor and WAY-181187
WAY-208466
WAY-208466 is a potent and highly selective full agonist of the 5-HT6 receptor.
See 5-HT receptor and WAY-208466
YM-348
YM-348 is an indazole derivative drug which acts as a potent and selective 5-HT2C receptor agonist, with an EC50 of 1nM and 15x selectivity over 5-HT2A, although it only has moderate selectivity of 3x over the closely related 5-HT2B receptor.
Yohimbine
Yohimbine, also known as quebrachine, is an indole alkaloid derived from the bark of the African tree Pausinystalia johimbe; also from the bark of the unrelated South American tree Aspidosperma quebracho-blanco.
See 5-HT receptor and Yohimbine
Zacopride
Zacopride is a potent antagonist at the 5-HT3 receptor and an agonist at the 5-HT4 receptor.
See 5-HT receptor and Zacopride
Ziprasidone
Ziprasidone, sold under the brand name Geodon among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder.
See 5-HT receptor and Ziprasidone
Zolmitriptan
Zolmitriptan, sold under the brand name Zomig among others, is a triptan used in the acute treatment of migraine attacks with or without aura and cluster headaches.
See 5-HT receptor and Zolmitriptan
1-(2-Diphenyl)piperazine
1-(2-Diphenyl)piperazine, also known as RA-7, is a drug which acts as a potent and selective antagonist at the 7 serotonin receptor.
See 5-HT receptor and 1-(2-Diphenyl)piperazine
2,5-Dimethoxy-4-methylamphetamine
2,5-Dimethoxy-4-methylamphetamine (DOM; known as STP, standing for "Serenity, Tranquility and Peace") is a psychedelic and a substituted amphetamine.
See 5-HT receptor and 2,5-Dimethoxy-4-methylamphetamine
2-Methyl-5-hydroxytryptamine
2-Methyl-5-hydroxytryptamine (2-Methylserotonin, 2-Methyl-5-HT) is a tryptamine derivative closely related to the neurotransmitter serotonin which acts as a moderately selective full agonist at the 5-HT3 receptor.
See 5-HT receptor and 2-Methyl-5-hydroxytryptamine
25I-NBOMe
25I-NBOMe (2C-I-NBOMe, Cimbi-5, and also shortened to "25I"), also known as Smiles, or N-Bomb, is a novel synthetic psychoactive substance with strong hallucinogenic properties, synthesized in 2003 for research purposes.
See 5-HT receptor and 25I-NBOMe
2C-B
2C-B (4-bromo-2,5-dimethoxyphenethylamine), also known as Nexus, is a synthetic psychedelic drug of the 2C family, mainly used as a recreational drug.
5-Carboxamidotryptamine
5-Carboxamidotryptamine (5-CT) is a tryptamine derivative closely related to the neurotransmitter serotonin.
See 5-HT receptor and 5-Carboxamidotryptamine
5-HT1 receptor
The 5-HT1 receptors are a subfamily of the 5-HT serotonin receptors that bind to the endogenous neurotransmitter serotonin (also known as 5-hydroxytryptamine, or 5-HT). 5-HT receptor and 5-HT1 receptor are serotonin receptors.
See 5-HT receptor and 5-HT1 receptor
5-HT1A receptor
The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter. 5-HT receptor and 5-HT1A receptor are serotonin receptors.
See 5-HT receptor and 5-HT1A receptor
5-HT1B receptor
5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene. 5-HT receptor and 5-HT1B receptor are serotonin receptors.
See 5-HT receptor and 5-HT1B receptor
5-HT1D receptor
5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it. 5-HT receptor and 5-HT1D receptor are serotonin receptors.
See 5-HT receptor and 5-HT1D receptor
5-HT1E receptor
5-hydroxytryptamine (serotonin) 1E receptor (5-HT1E) is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family (Gi-coupled serotonin receptor). 5-HT receptor and 5-HT1E receptor are serotonin receptors.
See 5-HT receptor and 5-HT1E receptor
5-HT1F receptor
5-hydroxytryptamine (serotonin) receptor 1F, also known as HTR1F is a 5-HT1 receptor protein and also denotes the human gene encoding it. 5-HT receptor and 5-HT1F receptor are serotonin receptors.
See 5-HT receptor and 5-HT1F receptor
5-HT2 receptor
The 5-HT2 receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). 5-HT receptor and 5-HT2 receptor are serotonin receptors.
See 5-HT receptor and 5-HT2 receptor
5-HT2A receptor
The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). 5-HT receptor and 5-HT2A receptor are serotonin receptors.
See 5-HT receptor and 5-HT2A receptor
5-HT2B receptor
5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene. 5-HT receptor and 5-HT2B receptor are serotonin receptors.
See 5-HT receptor and 5-HT2B receptor
5-HT2C receptor
The 5-HT2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). 5-HT receptor and 5-HT2C receptor are serotonin receptors.
See 5-HT receptor and 5-HT2C receptor
5-HT3 receptor
The 5-HT3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin receptors) which are G protein-coupled receptors. 5-HT receptor and 5-HT3 receptor are serotonin receptors.
See 5-HT receptor and 5-HT3 receptor
5-HT4 receptor
5-Hydroxytryptamine receptor 4 is a protein that in humans is encoded by the HTR4 gene. 5-HT receptor and 5-HT4 receptor are serotonin receptors.
See 5-HT receptor and 5-HT4 receptor
5-HT5A receptor
5-Hydroxytryptamine (serotonin) receptor 5A, also known as HTR5A, is a protein that in humans is encoded by the HTR5A gene. 5-HT receptor and 5-HT5A receptor are serotonin receptors.
See 5-HT receptor and 5-HT5A receptor
5-HT5B receptor
5-HT5B receptor is a 5-HT receptor protein and the gene which encodes it. 5-HT receptor and 5-HT5B receptor are serotonin receptors.
See 5-HT receptor and 5-HT5B receptor
5-HT6 receptor
The 5HT6 receptor is a subtype of 5HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5HT). 5-HT receptor and 5-HT6 receptor are serotonin receptors.
See 5-HT receptor and 5-HT6 receptor
5-HT7 receptor
The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). 5-HT receptor and 5-HT7 receptor are serotonin receptors.
See 5-HT receptor and 5-HT7 receptor
5-MeO-DMT
5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) or O-methyl-bufotenin is a psychedelic of the tryptamine class.
See 5-HT receptor and 5-MeO-DMT
5-Methoxytryptamine
5-Methoxytryptamine (5-MT), also known as mexamine, is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin.
See 5-HT receptor and 5-Methoxytryptamine
6-APB
6-APB (6-(2-aminopropyl)benzofuran) is an empathogenic psychoactive compound of the substituted benzofuran and substituted phenethylamine classes.
8-OH-DPAT
8-OH-DPAT is a research chemical of the aminotetralin chemical class which was developed in the 1980s and has been widely used to study the function of the 5-HT1A receptor.
See 5-HT receptor and 8-OH-DPAT
See also
Serotonin receptors
- 5-HT receptor
- 5-HT1 receptor
- 5-HT1A receptor
- 5-HT1B receptor
- 5-HT1D receptor
- 5-HT1E receptor
- 5-HT1F receptor
- 5-HT2 receptor
- 5-HT2A receptor
- 5-HT2B receptor
- 5-HT2C receptor
- 5-HT3 receptor
- 5-HT4 receptor
- 5-HT5A receptor
- 5-HT5B receptor
- 5-HT6 receptor
- 5-HT7 receptor
- HTR3A
- HTR3B
- HTR3C
- HTR3D
- HTR3E
References
Also known as 5-HT receptor 4, 5-HT receptors, 5-HT1 like, 5-Hydroxytryptamine receptor, 5-carboxytryptamine, 5-ct, 5HT receptor, 5HT-3 receptor, 5HT-4 receptor, 5ht-receptor, 5ht-receptors, 5ht4, 5htr, Receptors, serotonin, Serotonin plasma membrane transport proteins, Serotonin r, Serotonin receptor, Serotonin receptors.
, CP-93129, CP-94253, Cyanopindolol, Cyclic adenosine monophosphate, Cyproheptadine, Dazopride, Depolarization, Diglyceride, Dihydroergotamine, Dolasetron, Dopamine, Doxepin, E-55888, E-6837, EGIS-12,233, Eletriptan, Eltoprazine, EMD-386088, EMDT, Empathogen, Eplivanserin, Ergometrine, Ergotamine, Etoperidone, F-15,599, Fenfluramine, Flesinoxan, Fluoxetine, Frovatriptan, G protein-coupled receptor, GABA, Gastrointestinal tract, Gepirone, Gi alpha subunit, Glossary of biology, Glutamic acid, Gq alpha subunit, GR-127935, Granisetron, Gs alpha subunit, Hallucinogen, Haloperidol, Heteroreceptor, Hydroxyzine, Hypnotic, Iloperidone, Imipramine, Inositol trisphosphate, Iodocyanopindolol, Ion channel, Ipsapirone, Isamoltane, Ketanserin, Lasmiditan, Latrepirdine, Lecozotan, Ligand (biochemistry), Ligand-gated ion channel, Lisuride, Lorcaserin, LSD, LY-334370, Lysine, MDMA, Mefway (18F), Memantine, Mescaline, Metergoline, Methylergometrine, Methylphenidate, Methysergide, Metitepine, Metoclopramide, Mianserin, Migraine, Mirtazapine, Mood (psychology), Mosapride, MS-245, NAN-190, Naratriptan, Nebivolol, Nefazodone, Nematode, Neurotransmission, Neurotransmitter, Nootropic, Noradrenergic and specific serotonergic antidepressant, Norepinephrine, Norfenfluramine, Olanzapine, Ondansetron, Oxprenolol, Oxytocin, Paroxetine, Partial agonist, Peripheral nervous system, Piboserod, Pieris rapae, Pimavanserin, Pindolol, Pizotifen, Platelet, PNU-22394, Potassium, Prokinetic agent, Prolactin, Propranolol, Protein Data Bank, Prucalopride, Pseudogene, Psilocin, Psilocybin, Psychedelic drug, Quetiapine, Quipazine, Rauwolscine, Receptor antagonist, Renzapride, Risperidone, Ritanserin, Rizatriptan, Ro 04-6790, Ro60-0175, RS-127445, RS-56812, RS-67,333, RU-24,969, SB-216641, SB-242084, SB-258585, SB-269970, SB-271046, SB-357134, SB-399885, SB-699551, Second messenger system, Serotonin, Serotonin antagonist and reuptake inhibitor, Serotonin syndrome, Smooth muscle, Sodium, Substance P, Sumatriptan, Tandospirone, Tegaserod, Thermoregulation, Tramadol, Trazodone, Trifluoromethylphenylpiperazine, Triptan, Tropisetron, Valerenic acid, Vasopressin, Vilazodone, Vortioxetine, WAY-100135, WAY-100635, WAY-181187, WAY-208466, YM-348, Yohimbine, Zacopride, Ziprasidone, Zolmitriptan, 1-(2-Diphenyl)piperazine, 2,5-Dimethoxy-4-methylamphetamine, 2-Methyl-5-hydroxytryptamine, 25I-NBOMe, 2C-B, 5-Carboxamidotryptamine, 5-HT1 receptor, 5-HT1A receptor, 5-HT1B receptor, 5-HT1D receptor, 5-HT1E receptor, 5-HT1F receptor, 5-HT2 receptor, 5-HT2A receptor, 5-HT2B receptor, 5-HT2C receptor, 5-HT3 receptor, 5-HT4 receptor, 5-HT5A receptor, 5-HT5B receptor, 5-HT6 receptor, 5-HT7 receptor, 5-MeO-DMT, 5-Methoxytryptamine, 6-APB, 8-OH-DPAT.