43 relations: Alexander Shulgin, Allyl group, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Amine, Controlled substance, Cytochrome P450, DALT, Dopamine transporter, Erowid, Ethyl group, Federal Analogue Act, Florida, Histamine H1 receptor, Indole, IUPAC nomenclature of organic chemistry, Κ-opioid receptor, Japan, Ligand (biochemistry), Louisiana, Medical Products Agency (Sweden), Methoxy group, Monoamine reuptake inhibitor, Pharmaceutical Affairs Act (Japan), Propene, Psychedelic drug, Research chemical, Riksdag, Serotonin transporter, Sigma-1 receptor, Sigma-2 receptor, Tryptamine, United States, 5-HT1A receptor, 5-HT1D receptor, 5-HT1E receptor, 5-HT2A receptor, 5-HT2B receptor, 5-HT2C receptor, 5-HT6 receptor, 5-MeO-DPT, 5-Methoxy-diisopropyltryptamine.
Alexander Theodore "Sasha" Shulgin (June 17, 1925 June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author.
An allyl group is a substituent with the structural formula H2C.
The alpha-2A adrenergic receptor (α2A adrenoceptor), also known as ADRA2A, is an α2 adrenergic receptor, and also denotes the human gene encoding it.
The alpha-2B adrenergic receptor (α2B adrenoceptor), is a G-protein coupled receptor.
The alpha-2C adrenergic receptor (α2C adrenoceptor), also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding it.
In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.
A controlled substance is generally a drug or chemical whose manufacture, possession, or use is regulated by a government, such as illicitly used drugs or prescription medications that are designated a Controlled Drug in the United Kingdom.
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
N,N-Diallyltryptamine (DALT) is a tryptamine derivative.
The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.
Erowid, also called Erowid Center, is a 501(c)(3) non-profit educational organization that provides information about psychoactive plants and chemicals as well as activities and technologies that can produce altered states of consciousness such as meditation, lucid dreaming, transcranial magnetic stimulation, and electroceuticals.
In chemistry, an ethyl group is an alkyl substituent derived from ethane (C2H6).
The Federal Analogue Act,, is a section of the United States Controlled Substances Act passed in 1986 which allowed any chemical "substantially similar" to a controlled substance listed in Schedule I or II to be treated as if it were also listed in those schedules, but only if intended for human consumption.
Florida (Spanish for "land of flowers") is the southernmost contiguous state in the United States.
The H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors.
Indole is an aromatic heterocyclic organic compound with formula C8H7N.
In chemical nomenclature, the IUPAC nomenclature of organic chemistry is a systematic method of naming organic chemical compounds as recommended by the International Union of Pure and Applied Chemistry (IUPAC).
The κ-opioid receptor (KOR) is a G protein-coupled receptor that in humans is encoded by the OPRK1 gene.
Japan (日本; Nippon or Nihon; formally 日本国 or Nihon-koku, lit. "State of Japan") is a sovereign island country in East Asia.
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
Louisiana is a state in the southeastern region of the United States.
The Medical Products Agency (Läkemedelsverket) is the government agency in Sweden responsible for regulation and surveillance of the development, manufacturing and sale of medicinal drugs, medical devices and cosmetics.
A methoxy group is the functional group consisting of a methyl group bound to oxygen.
A monoamine reuptake inhibitor (MRI) is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin, norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).
The of Japan is a law regulating the manufacturing, importation, and sale of drugs and medical devices.
Propene, also known as propylene or methyl ethylene, is an unsaturated organic compound having the chemical formula C3H6.
Psychedelics are a class of drug whose primary action is to trigger psychedelic experiences via serotonin receptor agonism, causing thought and visual/auditory changes, and altered state of consciousness.
Research chemicals are chemical substances used by scientists for medical and scientific research purposes.
The Riksdag (riksdagen or Sveriges riksdag) is the national legislature and the supreme decision-making body of Sweden.
The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.
The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor.
The sigma-2 receptor (σ2R) is a sigma receptor subtype that has been found highly expressed in malignant cancer cells, and is currently under investigation for its potential diagnostic and therapeutic uses.
Tryptamine is a monoamine alkaloid.
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).
5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it.
5-hydroxytryptamine (serotonin) 1E receptor (5-HT1E) is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family (Gi-coupled serotonin receptor).
The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).
5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene.
The 5-HT2C receptor is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).
The 5HT6 receptor is a subtype of 5HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5HT).
5-MeO-DPT (also known as 5-methoxy-N,N-Dipropyltryptamine), is a psychedelic and entheogenic drug.
5-methoxy-diisopropyltryptamine (5-MeO-DiPT), sometimes called "Foxy", is a psychedelic tryptamine.