39 relations: APOBEC, Bisulfite, Bisulfite sequencing, Calf, CpG site, Cytosine, Deamination, DNA, DNA methyltransferase, Epigenetics, Eukaryote, Gene expression, Guanine, Hydrolysis, Methyl group, Methylation, Mycobacterium tuberculosis, National Center for Biotechnology Information, Nitrogen, Nitrous acid, Nucleic acid, Nucleoside, Paper chromatography, Restriction enzyme, RNA, Rollin Hotchkiss, Sulfuric acid, Thymine, Thymus, Toxin, Transcription (biology), Transition (genetics), Treat Baldwin Johnson, Tuberculinic acid, Tuberculosis, Uracil, Vertebrate, 5-Hydroxymethylcytosine, 5-Methylcytidine.
Bisulfite ion (IUPAC-recommended nomenclature: hydrogen sulfite) is the ion HSO3−.
Bisulfite sequencing (also known as bisulphite sequencing) is the use of bisulfite treatment of DNA to determine its pattern of methylation.
A calf (plural, calves) is the young of domestic cattle.
The CpG sites or CG sites are regions of DNA where a cytosine nucleotide is followed by a guanine nucleotide in the linear sequence of bases along its 5' → 3' direction.
Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).
Deamination is the removal of an amine group from a protein molecule.
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
In biochemistry, the DNA methyltransferase (DNA MTase) family of enzymes catalyze the transfer of a methyl group to DNA.
Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence.
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
Guanine (or G, Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).
Hydrolysis is a term used for both an electro-chemical process and a biological one.
A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.
In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.
Mycobacterium tuberculosis is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis.
The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH).
Nitrogen is a chemical element with symbol N and atomic number 7.
Nitrous acid (molecular formula HNO2) is a weak and monobasic acid known only in solution and in the form of nitrite salts.
Nucleic acids are biopolymers, or small biomolecules, essential to all known forms of life.
Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group.
Paper chromatography is an analytical method used to separate colored chemicals or substances.
A restriction enzyme or restriction endonuclease is an enzyme that cleaves DNA into fragments at or near specific recognition sites within the molecule known as restriction sites.
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
Rollin Douglas Hotchkiss (1911 – December 12, 2004) was an American biochemist who helped to establish the role of DNA as the genetic material and contributed to the isolation and purification of the first antibiotics.
Sulfuric acid (alternative spelling sulphuric acid) is a mineral acid with molecular formula H2SO4.
---> Thymine (T, Thy) is one of the four nucleobases in the nucleic acid of DNA that are represented by the letters G–C–A–T.
The thymus is a specialized primary lymphoid organ of the immune system.
A toxin (from toxikon) is a poisonous substance produced within living cells or organisms; synthetic toxicants created by artificial processes are thus excluded.
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
In genetics, a transition is a point mutation that changes a purine nucleotide to another purine (A ↔ G) or a pyrimidine nucleotide to another pyrimidine (C ↔ T).
Treat Baldwin Johnson (1875-1947) was an American chemist, born at Bethany, Connecticut.
Tuberculinic acid is a noncanonical nucleic acid initially identified as the poison of Tubercle bacillus (.
Tuberculosis (TB) is an infectious disease usually caused by the bacterium Mycobacterium tuberculosis (MTB).
Uracil (U) is one of the four nucleobases in the nucleic acid of RNA that are represented by the letters A, G, C and U. The others are adenine (A), cytosine (C), and guanine (G).
Vertebrates comprise all species of animals within the subphylum Vertebrata (chordates with backbones).
5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base derived from cytosine.
5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine.