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51 relations: Agonist, Anxiety, Chemical structure, Circulatory system, Cocaine, Cocaine dependence, Cranial cavity, Derivative (chemistry), Dopamine, EC50, Exocytosis, Federal Analogue Act, Head-twitch response, Hyperthermia, In vitro, Insomnia, Intrinsic activity, Α,N,N-Trimethyltryptamine, MDMA, Monoamine oxidase inhibitor, Monoamine releasing agent, Naphthylaminopropane, Neurotoxicity, Norepinephrine, Para-Methoxyamphetamine, Psychedelic drug, Rhesus macaque, Self-administration, Serotonergic, Serotonin, Serotonin-norepinephrine-dopamine releasing agent, Serotonin–dopamine releasing agent, Side effect, Structural analog, Substance abuse, Substituted phenethylamine, Sympathomimetic drug, Synaptosome, Tryptamine, United States, 4-HO-αMT, 4-Me-αMT, 4-Methyl-α-ethyltryptamine, 5-Fluoro-AMT, 5-HT receptor, 5-HT2A receptor, 5-IT, 5-MeO-AET, 5-MeO-aMT, 6-Fluoro-AMT, ..., 7-Methyl-α-ethyltryptamine. Expand index (1 more) »
Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
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Anxiety
Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behaviour such as pacing back and forth, somatic complaints, and rumination.
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Chemical structure
A chemical structure determination includes a chemist's specifying the molecular geometry and, when feasible and necessary, the electronic structure of the target molecule or other solid.
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Circulatory system
The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.
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Cocaine
Cocaine, also known as coke, is a strong stimulant mostly used as a recreational drug.
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Cocaine dependence
Cocaine dependence is a psychological desire to use cocaine regularly.
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Cranial cavity
The cranial cavity, also known as intracranial space, is the space within the skull.
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Derivative (chemistry)
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
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Dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
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EC50
Half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time.
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Exocytosis
Exocytosis is a form of active transport in which a cell transports molecules (e.g., neurotransmitters and proteins) out of the cell (exo- + cytosis) by expelling them through an energy-dependent process.
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Federal Analogue Act
The Federal Analogue Act,, is a section of the United States Controlled Substances Act passed in 1986 which allowed any chemical "substantially similar" to a controlled substance listed in Schedule I or II to be treated as if it were also listed in those schedules, but only if intended for human consumption.
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Head-twitch response
The head-twitch response (HTR) is a rapid side-to-side head movement that occurs in mice and rats after the serotonin 5-HT2A receptor is activated.
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Hyperthermia
Hyperthermia is elevated body temperature due to failed thermoregulation that occurs when a body produces or absorbs more heat than it dissipates.
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In vitro
In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
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Insomnia
Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.
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Intrinsic activity
Intrinsic activity (IA) or efficacy refers to the relative ability of a drug-receptor complex to produce a maximum functional response.
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Α,N,N-Trimethyltryptamine
α,N,N-Trimethyltryptamine (α,N,N-TMT, α-TMT, ATMT) is a psychoactive drug of the tryptamine chemical class which acts as a psychedelic hallucinogen.
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MDMA
3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E), is a psychoactive drug used primarily as a recreational drug.
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Monoamine oxidase inhibitor
Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B).
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Monoamine releasing agent
A monoamine releasing agent (MRA), or simply monoamine releaser, is a drug that induces the release of a monoamine neurotransmitter from the presynaptic neuron into the synapse, leading to an increase in the extracellular concentrations of the neurotransmitter.
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Naphthylaminopropane
Naphthylisopropylamine (PAL-287) is an experimental drug currently under investigation for the treatment of alcohol and stimulant addiction.
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Neurotoxicity
Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system.
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Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
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Para-Methoxyamphetamine
para-Methoxyamphetamine (PMA; "Death", "Dr. Death"), also known as 4-methoxyamphetamine (4-MA), is a designer drug of the amphetamine class with serotonergic effects.
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Psychedelic drug
Psychedelics are a class of drug whose primary action is to trigger psychedelic experiences via serotonin receptor agonism, causing thought and visual/auditory changes, and altered state of consciousness.
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Rhesus macaque
The rhesus macaque (Macaca mulatta) is one of the best-known species of Old World monkeys.
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Self-administration
Self-administration is, in its medical sense, the process of a subject administering a pharmacological substance to him-, her-, or itself.
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Serotonergic
Serotonergic or serotoninergic means "pertaining to or affecting serotonin".
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Serotonin
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
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Serotonin-norepinephrine-dopamine releasing agent
A serotonin–norepinephrine-dopamine releasing agent (SNDRA), also known as a triple releasing agent (TRA), is a type of drug which induces the release of serotonin, norepinephrine/epinephrine, and dopamine in the brain and body.
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Serotonin–dopamine releasing agent
A serotonin–dopamine releasing agent (SDRA) is a type of drug which induces the release of serotonin and dopamine in the body and/or brain.
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Side effect
In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.
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Structural analog
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
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Substance abuse
Substance abuse, also known as drug abuse, is a patterned use of a drug in which the user consumes the substance in amounts or with methods which are harmful to themselves or others, and is a form of substance-related disorder.
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Substituted phenethylamine
Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; the class is composed of all the derivative compounds of phenethylamine which can be formed by replacing, or substituting, one or more hydrogen atoms in the phenethylamine core structure with substituents.
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Sympathomimetic drug
Sympathomimetic drugs (also known as adrenergic drugs and adrenergic amines) are stimulant compounds which mimic the effects of endogenous agonists of the sympathetic nervous system.
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Synaptosome
A synaptosome is an isolated synaptic terminal from a neuron.
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Tryptamine
Tryptamine is a monoamine alkaloid.
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United States
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
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4-HO-αMT
4-Hydroxy-α-methyltryptamine (4-HO-αMT) is a psychedelic drug of the tryptamine class.
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4-Me-αMT
4-Methyl-αMT (4-Me-αMT), also known as 4,α-dimethyltryptamine (4,α-DMT), and MP-809, is a drug belonging to the tryptamine class that was investigated as an antidepressant in the early 1960s but was never marketed.
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4-Methyl-α-ethyltryptamine
4-Methyl-α-ethyltryptamine (4-Me-αET) is a putative stimulant, psychedelic, and entactogen drug of the tryptamine class.
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5-Fluoro-AMT
5-Fluoro-α-methyltryptamine (5-Fluoro-αMT), also known as PAL-544, is a putative stimulant, entactogen, and psychedelic tryptamine derivative related to α-methyltryptamine (αMT).
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5-HT receptor
5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.
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5-HT2A receptor
The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).
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5-IT
5-(2-Aminopropyl)indole (5-API, 5-IT, PAL-571) is an indole and phenethylamine derivative with empathogenic effects.
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5-MeO-AET
5-Methoxy-alpha-ethyltryptamine (5-MeO-α-ET) is a psychoactive drug and member of the tryptamine chemical class.
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5-MeO-aMT
5-MeO-aMT or 5-methoxy-α-methyltryptamine, α,O-Dimethylserotonin (Alpha-O) is a potent psychedelic tryptamine.
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6-Fluoro-AMT
6-Fluoro-α-methyltryptamine (6-fluoro-AMT) is a tryptamine derivative related to compounds such as alpha-methyltryptamine and 5-MeO-AMT, which has been sold as a designer drug.
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7-Methyl-α-ethyltryptamine
7-Methyl-α-ethyltryptamine (7-Me-αET) is a tryptamine derivative related to α-ethyltryptamine (αET).
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Redirects here:
5-Chloro-AMT, 5-Chloro-aMT, 5-Chloro-alpha-methyltryptamine, 5-Chloro-α-methyltryptamine, 5-chloro-AMT, 5-chloro-aMT, 5-chloro-alpha-methyltryptamine, 5-chloro-α-methyltryptamine, 5-chloro-αMT, PAL-542.
References
[1] https://en.wikipedia.org/wiki/5-Chloro-αMT
