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6,14-Endoethenotetrahydrooripavine is the central nucleus, or backbone, of a class of morphinan opioids known as the Bentley compounds and may be considered their "privileged scaffold". [1]

10 relations: Acetorphine, Bentley compounds, Buprenorphine, Congener (chemistry), Etorphine, Morphinan, Opioid, Oripavine, Thebaine, Thienorphine.


Acetorphine is a potent opioid analgesic, up to 8700 times stronger than morphine by weight.

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Bentley compounds

The Bentley compounds are a class of semi-synthetic opioids that were first synthesized by K. W. Bentley by Diels-Alder reaction of thebaine with various dienophiles.

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Buprenorphine, sold under the brand name Subutex, among others, is an opioid used to treat opioid addiction, acute pain, and chronic pain.

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Congener (chemistry)

In chemistry, congeners are related chemical substances "related to each other by origin, structure, or function".

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Etorphine (M99) is a semi-synthetic opioid possessing an analgesic potency approximately 1,000–3,000 times that of morphine.

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Morphinan is the prototype chemical structure of a large chemical class of psychoactive drugs, consisting of opiate analgesics, cough suppressants, and dissociative hallucinogens, among others.

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Opioids are substances that act on opioid receptors to produce morphine-like effects.

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Oripavine is an opiate and the major metabolite of thebaine.

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Thebaine (paramorphine), also known as codeine methyl enol ether, is an opiate alkaloid, its name coming from the Greek Θῆβαι, Thēbai (Thebes), an ancient city in Upper Egypt.

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Thienorphine is a very potent, extremely long-acting, orally-active opioid analgesic with mixed agonist–antagonist properties which was developed by the Beijing Institute of Pharmacology and Toxicology as a potential treatment for opioid dependence.

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[1] https://en.wikipedia.org/wiki/6,14-Endoethenotetrahydrooripavine

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