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DNQX

Index DNQX

DNQX (6,7-dinitroquinoxaline-2,3-dione) is a competitive antagonist at AMPA and kainate receptors, two ionotropic glutamate receptor (iGluR) subfamilies. [1]

9 relations: AMPA, CNQX, Ion channel, Ionotropic glutamate receptor, Kainic acid, Molecular biology, Neurophysiology, Quinoxalinedione, Receptor antagonist.

AMPA

AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) is a compound that is a specific agonist for the AMPA receptor, where it mimics the effects of the neurotransmitter glutamate.

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CNQX

CNQX or cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione) is a competitive AMPA/kainate receptor antagonist.

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Ion channel

Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore.

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Ionotropic glutamate receptor

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.

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Kainic acid

Kainic acid, or kainate, is an acid that naturally occurs in some seaweed.

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Molecular biology

Molecular biology is a branch of biology which concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions.

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Neurophysiology

Neurophysiology (from Greek νεῦρον, neuron, "nerve"; φύσις, physis, "nature, origin"; and -λογία, -logia, "knowledge") is a branch of physiology and neuroscience that is concerned with the study of the functioning of the nervous system.

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Quinoxalinedione

Quinoxalinedione is an organic compound with the formula C6H4(NH)2(CO)2.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Redirects here:

6,7-Dinitroquinoxaline-2,3-dione, 6,7-dinitroquinoxaline-2,3-dione.

References

[1] https://en.wikipedia.org/wiki/DNQX

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