23 relations: Alexander Shulgin, Amphetamine, Dopamine, Drug, EDMA, Federal Analogue Act, IC50, In vitro, MBDB, MMAI, Mouth, Norepinephrine, Pharmacokinetics, Reuptake, Reuptake inhibitor, Serotonin, Serotonin releasing agent, Structural analog, Substituted amphetamine, Thermodynamic activity, United States, 1,4-Benzodioxine, 2-Aminotetralin.
Alexander Theodore "Sasha" Shulgin (June 17, 1925 June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author.
Amphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.
3,4-Ethylenedioxy-N-methylamphetamine (EDMA) is an entactogen drug of the amphetamine class.
The Federal Analogue Act,, is a section of the United States Controlled Substances Act passed in 1986 which allowed any chemical "substantially similar" to a controlled substance listed in Schedule I or II to be treated as if it were also listed in those schedules, but only if intended for human consumption.
The half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.
In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
1,3-Benzodioxolyl-N-methylbutanamine (N-methyl-1,3-benzodioxolylbutanamine, MBDB, 3,4-methylenedioxy-N-methyl-α-ethylphenylethylamine) is an entactogen of the phenethylamine chemical class.
5-Methoxy-6-methyl-2-aminoindane (MMAI), is a drug developed in the 1990s by a team led by David E. Nichols at Purdue University.
In animal anatomy, the mouth, also known as the oral cavity, buccal cavity, or in Latin cavum oris, is the opening through which many animals take in food and issue vocal sounds.
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.
Reuptake is the reabsorption of a neurotransmitter by a neurotransmitter transporter located along the plasma membrane of an axon terminal (i.e., the pre-synaptic neuron at a synapse) or glial cell after it has performed its function of transmitting a neural impulse.
A reuptake inhibitor (RI) is a type of drug known as a reuptake modulator that inhibits the plasmalemmal transporter-mediated reuptake of a neurotransmitter from the synapse into the pre-synaptic neuron.
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
A serotonin releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft.
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
Substituted amphetamines are a class of compounds based upon the amphetamine structure; it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents.
In chemical thermodynamics, activity (symbol) is a measure of the "effective concentration" of a species in a mixture, in the sense that the species' chemical potential depends on the activity of a real solution in the same way that it would depend on concentration for an ideal solution.
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
1,4-Benzodioxine, in chemistry, especially organic chemistry, is an aromatic ring.
2-Aminotetralin (2-AT), also known as 1,2,3,4-tetrahydronaphthalen-2-amine (THN), is a stimulant drug with a chemical structure consisting of a tetralin group combined with an amine.
1-(6-Tetralinyl)-2-aminopropane, 1-(6-Tetralinyl)-2-propanamine, 1-(6-Tetralinyl)-2-propylamine, 1-(6-Tetralinyl)propan-2-amine, 1-(6-tetralinyl)-2-aminopropane, 1-(6-tetralinyl)-2-propanamine, 1-(6-tetralinyl)-2-propylamine, 1-(6-tetralinyl)propan-2-amine, 6-(2-Aminopropyl)tetralin, 6-Tetralinyl-2-aminopropane, 6-Tetralinylpropan-2-amine, 6-tetralinyl-2-aminopropane, 6-tetralinylpropan-2-amine, Aminopropyltetralin, Propylaminotetralin, Tetralinylaminopropane, Tetralinylisopropanamine, Tetralinylisopropylamine.