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6-Monoacetylcodeine

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6-Monoacetylcodeine (6-MAC) is an acetate ester of codeine in which the hydroxyl group on the 6 position has been acetylated. [1]

13 relations: Acetate, Acetic acid, Acetic anhydride, Acetylation, Catalysis, Codeine, Ester, Heroin, Hydroxy group, Morphine, Opium, Poppy tea, 6-Monoacetylmorphine.

Acetate

An acetate is a salt formed by the combination of acetic acid with an alkaline, earthy, metallic or nonmetallic and other base.

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Acetic acid

Acetic acid, systematically named ethanoic acid, is a colourless liquid organic compound with the chemical formula CH3COOH (also written as CH3CO2H or C2H4O2).

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Acetic anhydride

Acetic anhydride, or ethanoic anhydride, is the chemical compound with the formula (CH3CO)2O.

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Acetylation

Acetylation (or in IUPAC nomenclature ethanoylation) describes a reaction that introduces an acetyl functional group into a chemical compound.

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Catalysis

Catalysis is the increase in the rate of a chemical reaction due to the participation of an additional substance called a catalysthttp://goldbook.iupac.org/C00876.html, which is not consumed in the catalyzed reaction and can continue to act repeatedly.

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Codeine

Codeine is an opiate used to treat pain, as a cough medicine, and for diarrhea. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen. Evidence does not support its use for acute cough suppression in children or adults. In Europe it is not recommended as a cough medicine in those under twelve years of age. It is generally taken by mouth. It typically starts working after half an hour with maximum effect at two hours. The total duration of its effects last for about four to six hours. Common side effects include vomiting, constipation, itchiness, lightheadedness, and drowsiness. Serious side effects may include breathing difficulties and addiction. It is unclear if its use in pregnancy is safe. Care should be used during breastfeeding as it may result in opiate toxicity in the baby. Its use as of 2016 is not recommended in children. Codeine works following being broken down by the liver into morphine. How quickly this occurs depends on a person's genetics. Codeine was discovered in 1832 by Pierre Jean Robiquet. In 2013 about 361,000 kilograms of codeine were produced while 249,000 kilograms were used. This makes it the most commonly taken opiate. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is between 0.04 and 0.29 USD per dose as of 2014. In the United States it costs about one dollar a dose. Codeine occurs naturally and makes up about 2% of opium.

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Ester

In chemistry, an ester is a chemical compound derived from an acid (organic or inorganic) in which at least one –OH (hydroxyl) group is replaced by an –O–alkyl (alkoxy) group.

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Heroin

Heroin, also known as diamorphine among other names, is an opioid most commonly used as a recreational drug for its euphoric effects.

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Hydroxy group

A hydroxy or hydroxyl group is the entity with the formula OH.

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Morphine

Morphine is a pain medication of the opiate variety which is found naturally in a number of plants and animals.

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Opium

Opium (poppy tears, with the scientific name: Lachryma papaveris) is the dried latex obtained from the opium poppy (scientific name: Papaver somniferum).

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Poppy tea

Poppy tea is any herbal tea infusion brewed from poppy straw or seeds of several species of poppy.

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6-Monoacetylmorphine

6-Monoacetylmorphine (6-MAM, 6-acetylmorphine, or 6-AM) is one of three active metabolites of heroin (diacetylmorphine), the others being morphine and the much less active 3-monoacetylmorphine (3-MAM).

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Redirects here:

6-MAC, 6-monoacetylcodeine, 6-monoacetylcodeine (6-MAC), 6MAC, Acetylcodeine, Monoacetylcodeine.

References

[1] https://en.wikipedia.org/wiki/6-Monoacetylcodeine

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