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51 relations: Acute leukemia, Acute lymphoblastic leukemia, Acute myeloid leukemia, Anemia, Anorexia (symptom), Antimetabolite, Australian Approved Name, Bone marrow suppression, British Approved Name, Cerebrospinal fluid, Chronic myelogenous leukemia, Cytotoxicity, Developing country, DNA, G protein, Genetic testing, Genetic variation, Goodman & Gilman's The Pharmacological Basis of Therapeutics, Guanine, Guanine deaminase, Health system, Hepatotoxicity, Hypoxanthine-guanine phosphoribosyltransferase, IMP dehydrogenase, Inflammatory bowel disease, International nonproprietary name, Lactation, Leukopenia, Liver disease, Liver function tests, Methylation, National Health Service, Nausea, Neutropenia, Pharmacogenetics, Pregnancy, Psoriasis, Purine analogue, RAC1, Red blood cell, Ribonucleotide reductase, RNA, Stomatitis, Thiopurine methyltransferase, Thiouric acid, Thrombocytopenia, Ulcerative colitis, United States Adopted Name, WHO Model List of Essential Medicines, Xanthine oxidase, ..., Zygosity. Expand index (1 more) »
Acute leukemia
Acute leukemia or acute leukaemia is a family of serious medical conditions relating to an original diagnosis of leukemia.
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Acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes.
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Acute myeloid leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells.
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Anemia
Anemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood, or a lowered ability of the blood to carry oxygen.
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Anorexia (symptom)
Anorexia (from Ancient Greek ανορεξία: 'ἀν-' "without" + 'όρεξις', spelled 'órexis' meaning "appetite") is the decreased sensation of appetite.
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Antimetabolite
An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism.
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Australian Approved Name
An Australian Approved Name (AAN) is a generic drug name set by the TGA for use in Australia.
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Bone marrow suppression
Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).
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British Approved Name
A British Approved Name (BAN) is the official non-proprietary or generic name given to a pharmaceutical substance, as defined in the British Pharmacopoeia (BP).
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Cerebrospinal fluid
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found in the brain and spinal cord.
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Chronic myelogenous leukemia
Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a cancer of the white blood cells.
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Cytotoxicity
Cytotoxicity is the quality of being toxic to cells.
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Developing country
A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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G protein
G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior.
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Genetic testing
Genetic testing, also known as DNA testing, allows the determination of bloodlines and the genetic diagnosis of vulnerabilities to inherited diseases.
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Genetic variation
Genetic variation means that biological systems – individuals and populations – are different over space.
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Goodman & Gilman's The Pharmacological Basis of Therapeutics
Goodman & Gilman's The Pharmacological Basis of Therapeutics, commonly referred to as the Blue Bible or Goodman & Gilman, is a textbook of pharmacology originally authored by Louis S. Goodman and Alfred Gilman.
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Guanine
Guanine (or G, Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).
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Guanine deaminase
Guanine deaminase also known as cypin, guanase, guanine aminase, GAH, and guanine aminohydrolase is an aminohydrolase enzyme which converts guanine to xanthine.
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Health system
A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.
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Hepatotoxicity
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.
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Hypoxanthine-guanine phosphoribosyltransferase
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene.
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IMP dehydrogenase
IMP dehydrogenase (Inosine-5'-monophosphate dehydrogenase) (Inosinic acid dehydrogenaseis) (IMPDH) an enzyme that converts inosine monophosphate to xanthosine monophosphate: It catalyzes the rate-limiting reaction of de novo GTP biosynthesis.
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Inflammatory bowel disease
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.
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International nonproprietary name
The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.
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Lactation
Lactation describes the secretion of milk from the mammary glands and the period of time that a mother lactates to feed her young.
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Leukopenia
Leukopenia is a decrease in the number of white blood cells (leukocytes) found in the blood, which places individuals at increased risk of infection.
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Liver disease
Liver disease (also called hepatic disease) is a type of damage to or disease of the liver.
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Liver function tests
Liver function tests (LFTs or LFs) are groups of blood tests that give information about the state of a patient's liver.
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Methylation
In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.
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National Health Service
The National Health Service (NHS) is the name used for each of the public health services in the United Kingdom – the National Health Service in England, NHS Scotland, NHS Wales, and Health and Social Care in Northern Ireland – as well as a term to describe them collectively.
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Nausea
Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.
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Neutropenia
Neutropenia or neutropaenia is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood.
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Pharmacogenetics
Pharmacogenetics is the study of inherited genetic differences in drug metabolic pathways which can affect individual responses to drugs, both in terms of therapeutic effect as well as adverse effects.
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Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
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Psoriasis
Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin.
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Purine analogue
Purine analogues are antimetabolites that mimic the structure of metabolic purines.
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RAC1
Rac1, also known as Ras-related C3 botulinum toxin substrate 1, is a protein found in human cells.
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Red blood cell
Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.
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Ribonucleotide reductase
Ribonucleotide reductase (RNR), also known as ribonucleoside diphosphate reductase (rNDP), is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides.
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RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
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Stomatitis
Stomatitis is inflammation of the mouth and lips.
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Thiopurine methyltransferase
Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT) is an enzyme that in humans is encoded by the TPMT gene.
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Thiouric acid
Thiouric acid, more accurately called 6-thiouric acid, is a main inactive metabolite of the immunosuppressive drugs azathioprine, mercaptopurine and tioguanine.
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Thrombocytopenia
Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes, also known as platelets, in the blood.
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Ulcerative colitis
Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum.
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United States Adopted Name
United States Adopted Names are unique nonproprietary names assigned to pharmaceuticals marketed in the United States.
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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Xanthine oxidase
Xanthine oxidase (XO, sometimes XAO) is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species.
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Zygosity
Zygosity is the degree of similarity of the alleles for a trait in an organism.
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Redirects here:
6-TG, 6-Thioguanine, 6-Tioguanine, 6-thioguanine, ATC code L01BB03, ATCvet code QL01BB03, C5H5N5S, Lanvis, Thioguanine, Wellcome U3B.
References
[1] https://en.wikipedia.org/wiki/Tioguanine
