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8 relations: Deuterium, Inverse agonist, Naloxone, Naltrexone, Nuclear magnetic resonance, Opioid, Receptor antagonist, 6β-Naltrexol.
Deuterium
Deuterium (or hydrogen-2, symbol or, also known as heavy hydrogen) is one of two stable isotopes of hydrogen (the other being protium, or hydrogen-1).
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Inverse agonist
In the field of pharmacology, an inverse agonist is an agent that binds to the same receptor as an agonist but induces a pharmacological response opposite to that agonist.
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Naloxone
Naloxone, sold under the brandname Narcan among others, is a medication used to block the effects of opioids, especially in overdose.
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Naltrexone
Naltrexone, sold under the brand names ReVia and Vivitrol among others, is a medication primarily used to manage alcohol or opioid dependence.
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Nuclear magnetic resonance
Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a magnetic field absorb and re-emit electromagnetic radiation.
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Opioid
Opioids are substances that act on opioid receptors to produce morphine-like effects.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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6β-Naltrexol
6β-Naltrexol, or 6α-hydroxynaltrexone, is a major active metabolite of naltrexone formed by hepatic dihydrodiol dehydrogenase which acts as a potent, peripherally selective opioid neutral antagonist.
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