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7+3 (chemotherapy)

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"7+3" in the context of chemotherapy is an acronym for a chemotherapy regimen that is most often used today (as of 2014) as first-line induction therapy (to induce remission) in acute myelogenous leukemia, excluding the acute promyelocytic leukemia form, which is better treated with ATRA and/or arsenic trioxide and requires less chemotherapy (if requires it at all, which is not always the case). [1]

31 relations: Acronym, Acute myeloid leukemia, Acute promyelocytic leukemia, ADE (chemotherapy), Anthracycline, Anthraquinone, Antibiotics, Arsenic trioxide, Chemotherapy, Chemotherapy regimen, Cure, Cyclophosphamide, Cytarabine, DAM (chemotherapy), DAT (chemotherapy), Daunorubicin, Doxorubicin, Enzyme, Etoposide, Glucocorticoid, Idarubicin, Melphalan, Mercaptopurine, Methotrexate, Mitoxantrone, Myeloperoxidase, Prednisolone, Tioguanine, Tretinoin, Vinblastine, Vincristine.


An acronym is an abbreviation, used as a word, which is formed from the initial components in a phrase or a word.

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Acute myeloid leukemia

Acute myeloid leukemia (AML), also known as acute myelogenous leukemia or acute nonlymphocytic leukemia (ANLL), is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.

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Acute promyelocytic leukemia

Acute promyelocytic leukemia (APML, APL) is the M3 subtype of acute myelogenous leukemia (AML), a cancer of the white blood cells.

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ADE (chemotherapy)

ADE is a chemotherapy regimen most often used as an induction or consolidation regimen in acute myelogenous leukemia, especially in poor-risk patients or those refractory to the standard first-line induction with standard "7+3" regimen or who are relapsed after the standard chemotherapy.

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Anthracyclines (or anthracycline antibiotics) are a class of drugs (CCNS or cell-cycle non-specific) used in cancer chemotherapy derived from Streptomyces bacterium Streptomyces peucetius var.

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Anthraquinone, also called anthracenedione or dioxoanthracene, is an aromatic organic compound with formula.

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Antibiotics or antibacterials are a type of antimicrobial used in the treatment and prevention of bacterial infection.

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Arsenic trioxide

Arsenic trioxide is an inorganic compound with the formula.

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Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a category of cancer treatment that uses chemical substances, especially one or more anti-cancer drugs (chemotherapeutic agents) that are given as part of a standardized chemotherapy regimen.

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Chemotherapy regimen

A chemotherapy regimen is a regimen for chemotherapy defining the drugs to be used, their dosage, the frequency and duration of treatments and other considerations.

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A cure is the end of a medical condition; the substance or procedure that ends the medical condition, such as a medication, a surgical operation, a change in lifestyle, or even a philosophical mindset that helps end a person's sufferings.

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Cyclophosphamide (INN, trade names Endoxan, Cytoxan, Neosar, Procytox, Revimmune, Cycloblastin), also known as cytophosphane and CP, is a nitrogen mustard alkylating agent from the oxazaphosphorine group.

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Cytarabine or cytosine arabinoside (Cytosar-U or Depocyt) is a chemotherapy agent used mainly in the treatment of cancers of white blood cells such as acute myeloid leukemia (AML) and non-Hodgkin lymphoma.

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DAM (chemotherapy)

DAM in the context of chemotherapy is an acronym that means a chemotherapy regimen most often used as an induction regimen in acute myelogenous leukemia, usually for those who are refractory to the standard "7+3" induction regimen or who has relapsed.

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DAT (chemotherapy)

DAT in the context of chemotherapy is an acronym that means a chemotherapy regimen most often used as an induction regimen in acute myelogenous leukemia, usually for those who are refractory to the standard "7+3" induction regimen or who has relapsed.

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Daunorubicin or daunomycin (marketed as cerubidine) is chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer.

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Doxorubicin (INN, AAN, BAN, USAN; trade name Adriamycin; pegylated liposomal form trade name Doxil or Caelyx; nonpegylated liposomal form trade name Myocet), also known as hydroxydaunorubicin and hydroxydaunomycin, is a drug used in cancer chemotherapy and derived by chemical semisynthesis from a bacterial species.

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Enzymes are macromolecular biological catalysts.

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Etoposide, etoposide phosphate or VP-16 (current brand name: Etopophos, according to FDA Orange Book) is a cytotoxic anticancer drug which belongs to the topoisomerase inhibitor drug class.

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Glucocorticoids (GCs) are a class of steroid hormones which bind to the glucocorticoid receptor (GR), that is present in almost every vertebrate animal cell.

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Idarubicin or 4-demethoxydaunorubicin is an anthracycline antileukemic drug.

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Melphalan (trade name Alkeran, in former USSR also known as Sarcolysin) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents.

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Mercaptopurine (also called 6-mercaptopurine, 6-MP or its brand name Purinethol) is an immunosuppressive medication.

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Methotrexate (INN, AAN, BAN and USAN), abbreviated MTX and formerly known as amethopterin, is an antimetabolite and antifolate drug.

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Mitoxantrone (INN, BAN, USAN; also known as Mitozantrone in Australia; trade name Novantrone) is an anthracenedione antineoplastic agent.

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Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene on chromosome 17.

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Prednisolone is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions.

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Tioguanine (INN, BAN), or thioguanine (AAN, USAN), commonly referred to as 6-thioguanine (6-TG) is a medication used to treat a number of types of leukemia.

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Tretinoin (etymology and pronunciation) is retinoic acid in pharmaceutical form.

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Vinblastine is a medication used to treat a number of types of cancer including: Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, and testicular cancer among others.

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Vincristine (marketed under the brandname Oncovin) is a chemotherapy medication used to treat a number of types of cancer. It is given intravenously and works by inhibiting mitosis (stopping cells from dividing properly), causing the cells to die. The drug accomplishes this by binding to the tubulin protein, stopping the cell from separating its chromosomes during the metaphase; the cell then undergoes apoptosis. Because cancer cells divide more rapidly than healthy cells, they are affected more by the drug. Most people experience some side effects from vincristine treatment. Commonly it causes a change in sensation, hair loss, constipation, difficulty walking, and headaches. It will likely cause harm to an infant if given during pregnancy. Vincristine is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. It was formerly known as leurocristine, sometimes abbreviated "VCR", and is a vinca alkaloid from the Madagascar periwinkle Catharanthus roseus (formerly named Vinca rosea).

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Redirects here:

7 + 3, 7 + 3 (chemotherapy), 7+3, DA (chemotherapy), DA cytostatic, DAC (chemotherapy), IA (chemotherapy), IAC (chemotherapy), MA (chemotherapy), MAC (chemotherapy).


[1] https://en.wikipedia.org/wiki/7%2B3_(chemotherapy)

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