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7-Dehydrocholesterol reductase

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7-dehydrocholesterol reductase, also known as DHCR7, is a protein that in humans is encoded by the DHCR7 gene. [1]

7 relations: Cholesterol, Enzyme, Gene, Nicotinamide adenine dinucleotide phosphate, Protein, Smith–Lemli–Opitz syndrome, 7-Dehydrocholesterol.


Cholesterol, from the Ancient Greek chole- (bile) and stereos (solid) followed by the chemical suffix -ol for an alcohol, is an organic molecule.

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Enzymes are macromolecular biological catalysts.

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A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity.

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Nicotinamide adenine dinucleotide phosphate

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.

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Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Smith–Lemli–Opitz syndrome

Smith–Lemli–Opitz syndrome (also SLOS, or 7-dehydrocholesterol reductase deficiency) is an inborn error of cholesterol synthesis.

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7-Dehydrocholesterol is a zoosterol that functions in the serum as a cholesterol precursor, and is converted to vitamin D3 in the skin, therefore functioning as provitamin-D3.

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7-dehydrocholesterol reductase, DHCR7, DHCR7 (gene).


[1] https://en.wikipedia.org/wiki/7-Dehydrocholesterol_reductase

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