15 relations: Adenosine A1 receptor, Adenosine A2A receptor, Adenosine receptor, Binding selectivity, Caffeine, CYP1A2, Dipropylcyclopentylxanthine, Drug, Phosphodiesterase inhibitor, Potency (pharmacology), Receptor antagonist, Stimulant, Xanthine, 8-Chlorotheophylline, 8-Cyclopentyl-1,3-dimethylxanthine.
The adenosine A1 receptor is one member of the adenosine receptor group of G protein-coupled receptors with adenosine as endogenous ligand.
The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, and also denotes the human gene encoding it.
The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as endogenous ligand.
Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.
Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class of psychoactive drugs.
New!!: 8-Phenyltheophylline and Caffeine ·
Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.
New!!: 8-Phenyltheophylline and CYP1A2 ·
8-Cyclopentyl-1,3-dipropylxanthine (DPCPX, PD-116,948) is a drug which acts as a potent and selective antagonist for the adenosine A1 receptor.
A drug is, in the broadest of terms, a chemical substance that has known biological effects on humans or other animals.
New!!: 8-Phenyltheophylline and Drug ·
A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), thereby preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s).
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens agonist-mediated responses rather than provoking a biological response itself upon binding to a receptor.
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both.
New!!: 8-Phenyltheophylline and Stimulant ·
Xanthine (or; archaically xanthic acid) (3,7-dihydro-purine-2,6-dione), is a purine base found in most human body tissues and fluids and in other organisms.
New!!: 8-Phenyltheophylline and Xanthine ·
8-Chlorotheophylline, also known as 1,3-dimethyl-8-chloroxanthine, is a stimulant drug of the xanthine chemical class, with physiological effects similar to caffeine.
8-Cyclopentyl-1,3-dimethylxanthine (8-Cyclopentyltheophylline, 8-CPT, CPX) is a drug which acts as a potent and selective antagonist for the adenosine receptors, with some selectivity for the A1 receptor subtype, as well as a non-selective phosphodiesterase inhibitor.