Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Free
Faster access than browser!
 

8-Phenyltheophylline

+ Save concept

8-Phenyltheophylline (8-phenyl-1,3-dimethylxanthine, 8-PT) is a drug derived from the xanthine family which acts as a potent and selective antagonist for the adenosine receptors A1 and A2A, but unlike other xanthine derivatives has virtually no activity as a phosphodiesterase inhibitor. [1]

16 relations: Adenosine A1 receptor, Adenosine A2A receptor, Adenosine receptor, Binding selectivity, Caffeine, CYP1A2, Dipropylcyclopentylxanthine, DMPX, Drug, Phosphodiesterase inhibitor, Potency (pharmacology), Receptor antagonist, Stimulant, Xanthine, 8-Chlorotheophylline, 8-Cyclopentyl-1,3-dimethylxanthine.

Adenosine A1 receptor

The adenosine A1 receptor is one member of the adenosine receptor group of G protein-coupled receptors with adenosine as endogenous ligand.

New!!: 8-Phenyltheophylline and Adenosine A1 receptor · See more »

Adenosine A2A receptor

The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, and also denotes the human gene encoding it.

New!!: 8-Phenyltheophylline and Adenosine A2A receptor · See more »

Adenosine receptor

The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as endogenous ligand.

New!!: 8-Phenyltheophylline and Adenosine receptor · See more »

Binding selectivity

Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

New!!: 8-Phenyltheophylline and Binding selectivity · See more »

Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.

New!!: 8-Phenyltheophylline and Caffeine · See more »

CYP1A2

Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.

New!!: 8-Phenyltheophylline and CYP1A2 · See more »

Dipropylcyclopentylxanthine

8-Cyclopentyl-1,3-dipropylxanthine (DPCPX, PD-116,948) is a drug which acts as a potent and selective antagonist for the adenosine A1 receptor.

New!!: 8-Phenyltheophylline and Dipropylcyclopentylxanthine · See more »

DMPX

DMPX (3,7-dimethyl-1-propargylxanthine) is a caffeine analog which displays affinity to A2 adenosine receptors, in contrast to the A1 subtype receptors.

New!!: 8-Phenyltheophylline and DMPX · See more »

Drug

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.

New!!: 8-Phenyltheophylline and Drug · See more »

Phosphodiesterase inhibitor

A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), thereby preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s).

New!!: 8-Phenyltheophylline and Phosphodiesterase inhibitor · See more »

Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

New!!: 8-Phenyltheophylline and Potency (pharmacology) · See more »

Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

New!!: 8-Phenyltheophylline and Receptor antagonist · See more »

Stimulant

Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have sympathomimetic effects.

New!!: 8-Phenyltheophylline and Stimulant · See more »

Xanthine

Xanthine (or; archaically xanthic acid) (3,7-dihydropurine-2,6-dione), is a purine base found in most human body tissues and fluids and in other organisms.

New!!: 8-Phenyltheophylline and Xanthine · See more »

8-Chlorotheophylline

8-Chlorotheophylline, also known as 1,3-dimethyl-8-chloroxanthine, is a stimulant drug of the xanthine chemical class, with physiological effects similar to caffeine.

New!!: 8-Phenyltheophylline and 8-Chlorotheophylline · See more »

8-Cyclopentyl-1,3-dimethylxanthine

8-Cyclopentyl-1,3-dimethylxanthine (8-Cyclopentyltheophylline, 8-CPT, CPX) is a drug which acts as a potent and selective antagonist for the adenosine receptors, with some selectivity for the A1 receptor subtype, as well as a non-selective phosphodiesterase inhibitor.

New!!: 8-Phenyltheophylline and 8-Cyclopentyl-1,3-dimethylxanthine · See more »

References

[1] https://en.wikipedia.org/wiki/8-Phenyltheophylline

OutgoingIncoming
Hey! We are on Facebook now! »