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29 relations: AB-CHFUPYCA, AB-FUBINACA, AB-PINACA, ADB-CHMINACA, ADB-PINACA, ADBICA, ADSB-FUB-187, Agonist, APICA (synthetic cannabinoid drug), APINACA, Butyl group, Cannabinoid receptor type 1, Cannabinoid receptor type 2, Designer drug, Drug Enforcement Administration, EC50, MDMB-CHMICA, MDMB-FUBINACA, Patent, PF-03550096, Pfizer, Propyl group, PX-3, STS-135 (drug), Synthetic cannabinoids, 5F-AB-PINACA, 5F-ADB, 5F-AMB, 5F-APINACA.
AB-CHFUPYCA
AB-CHFUPYCA (also AB-CHMFUPPYCA) is a compound that was first identified as a component of synthetic cannabis products in Japan in 2015.
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AB-FUBINACA
AB-FUBINACA is a drug that acts as a potent agonist for the cannabinoid receptors, with ''K''i values of 0.9 nM at CB1 and 23.2 nM at CB2 and EC50 values of 1.8 nM at CB1 and 3.2 nM at CB2.
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AB-PINACA
AB-PINACA is a compound that was first identified as a component of synthetic cannabis products in Japan in 2012.
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ADB-CHMINACA
ADB-CHMINACA (also known as MAB-CHMINACA) is an indazole-based synthetic cannabinoid.
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ADB-PINACA
ADB-PINACA is a cannabinoid designer drug that is an ingredient in some synthetic cannabis products.
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ADBICA
ADBICA (also known as ADB-PICA) is a designer drug identified in synthetic cannabis blends in Japan in 2013.
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ADSB-FUB-187
ADSB-FUB-187 is an indazole-based synthetic cannabinoid.
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Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
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APICA (synthetic cannabinoid drug)
APICA (2NE1, SDB-001, N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide) is an indole based drug that acts as a potent agonist for the cannabinoid receptors.
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APINACA
AKB48 (APINACA, N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide) is a drug that acts as a reasonably potent agonist for the cannabinoid receptors, with a Ki of 304.5nM and a EC50 of 585nM at CB1.
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Butyl group
In organic chemistry, butyl is a four-carbon alkyl radical or substituent group with general chemical formula −C4H9, derived from either of the two isomers of butane.
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Cannabinoid receptor type 1
The cannabinoid type 1 receptor, often abbreviated as CB1, is a G protein-coupled cannabinoid receptor located in the central and peripheral nervous system.
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Cannabinoid receptor type 2
The cannabinoid receptor type 2, abbreviated as CB2, is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene.
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Designer drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests.
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Drug Enforcement Administration
The Drug Enforcement Administration (DEA) is a United States federal law enforcement agency under the United States Department of Justice, tasked with combating drug smuggling and use within the United States.
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EC50
Half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time.
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MDMB-CHMICA
MDMB-CHMICA (also incorrectly known as MMB-CHMINACA) is an indole-based synthetic cannabinoid that is a potent agonist of the CB1 receptor and has been sold online as a designer drug.
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MDMB-FUBINACA
MDMB-FUBINACA (also known as MDMB(N)-Bz-F and FUB-MDMB) is an indazole-based synthetic cannabinoid that is a potent agonist for the cannabinoid receptors, with ''K''i values of 1.14 nM at CB1 and 0.1228 nM at CB2 and EC50 values of 0.2668 nM at CB1 and 0.1411 nM at CB2, and has been sold online as a designer drug.
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Patent
A patent is a set of exclusive rights granted by a sovereign state or intergovernmental organization to an inventor or assignee for a limited period of time in exchange for detailed public disclosure of an invention.
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PF-03550096
PF-03550096 is a drug that acts as a potent agonist for the CB2 cannabinoid receptor, with good selectivity over CB1 having Ki values of 7nM at CB2 and 1500nM at CB1.
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Pfizer
Pfizer Inc. is an American pharmaceutical conglomerate headquartered in New York City, with its research headquarters in Groton, Connecticut.
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Propyl group
In organic chemistry, propyl is a three-carbon alkyl substituent with chemical formula – for the linear form.
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PX-3
PX-3 (also known as APP-CHMINACA) is an indazole-based synthetic cannabinoid.
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STS-135 (drug)
STS-135 (N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide, also called 5F-APICA) is a designer drug offered by online vendors as a cannabimimetic agent.
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Synthetic cannabinoids
Synthetic cannabinoids are a class of molecules that bind to cannabinoid receptors in the body–the same receptors that the cannabinoids in cannabis plants, such as THC and CBD–attach to.
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5F-AB-PINACA
5F-AB-PINACA is an indazole-based synthetic cannabinoid that is derived from a series of compounds originally developed by Pfizer in 2009 as an analgesic medication, and has been sold online as a designer drug.
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5F-ADB
5F-ADB (also known as 5F-MDMB-PINACA) is an indazole-based synthetic cannabinoid from the indazole-3-carboxamide family, which has been used as an active ingredient in synthetic cannabis products and has been sold online as a designer drug.
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5F-AMB
5F-AMB (also known as 5F-MMB-PINACA and 5F-AMB-PINACA) is an indazole-based synthetic cannabinoid from the indazole-3-carboxamide family, which has been used as an active ingredient in synthetic cannabis products.
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5F-APINACA
5F-APINACA (also known as 5F-AKB48) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug.
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References
[1] https://en.wikipedia.org/wiki/ADB-FUBINACA
