Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
Aminolevulinic acid synthase (ALA synthase, ALAS, or delta-aminolevulinic acid synthase) is an enzyme that catalyzes the synthesis of D-aminolevulinic acid (ALA) the first common precursor in the biosynthesis of all tetrapyrroles such as hemes, cobalamins and chlorophylls.
Heme or haem is a coordination complex "consisting of an iron ion coordinated to a porphyrin acting as a tetradentate ligand, and to one or two axial ligands." The definition is loose, and many depictions omit the axial ligands.
In molecular biology, the iron response element or iron-responsive element (IRE) is a short conserved stem-loop which is bound by iron response proteins (IRPs, also named IRE-BP or IRBP).
The iron-responsive element-binding proteins, also known as IRE-BP, IRBP, IRP and IFR, bind to iron-responsive elements (IREs) in the regulation of human iron metabolism.
The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.
Sideroblastic anemia or sideroachrestic anemia is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes).