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Vadimezan

Index Vadimezan

Vadimezan (also known as or ASA404 and DMXAA) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression. [1]

16 relations: Breast cancer, Cancer, Chemotherapy, Cyclic guanosine monophosphate–adenosine monophosphate, Drug development, HER2/neu, Metastasis, Neoplasm, New Zealand, Non-small-cell lung carcinoma, Novartis, Phases of clinical research, Prostate cancer, Stimulator of interferon genes, University of Auckland, Vascular-targeting agent.

Breast cancer

Breast cancer is cancer that develops from breast tissue.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Cyclic guanosine monophosphate–adenosine monophosphate

Cyclic guanosine monophosphate–adenosine monophosphate (cyclic GMP-AMP, cGAMP) is the first cyclic di-nucleotide found in metazoa.

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Drug development

Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.

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HER2/neu

Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 (rodent), or ERBB2 (human), is a protein that in humans is encoded by the ERBB2 gene.

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Metastasis

Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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New Zealand

New Zealand (Aotearoa) is a sovereign island country in the southwestern Pacific Ocean.

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Non-small-cell lung carcinoma

Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC).

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Novartis

Novartis International AG is a Swiss multinational pharmaceutical company based in Basel, Switzerland.

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Phases of clinical research

The phases of clinical research are the steps in which scientists do experiments with a health intervention in an attempt to find enough evidence for a process which would be useful as a medical treatment.

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Prostate cancer

Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.

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Stimulator of interferon genes

Stimulator of interferon genes (STING), also known as transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a protein that in humans is encoded by the TMEM173 gene.

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University of Auckland

The University of Auckland (Te Whare Wānanga o Tāmaki Makaurau) is the largest university in New Zealand, located in the country's largest city, Auckland.

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Vascular-targeting agent

A vascular-targeting agent (VTA) or vascular disrupting agent (VDA) is a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis.

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Redirects here:

ASA404, C17H14O4, DMXAA.

References

[1] https://en.wikipedia.org/wiki/Vadimezan

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