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76 relations: Adrenergic receptor, Agonist, Alpha-1 adrenergic receptor, Alpha-2 adrenergic receptor, Antidepressant, Appetite, Basal ganglia, Bipolar disorder, Cell (biology), Chirality (chemistry), Depression and Anxiety, Dexpramipexole, Dissociation constant, Dizziness, Dopamine, Dopamine agonist, Dopamine receptor, Dopamine receptor D1, Dopamine receptor D2, Dopamine receptor D3, Dopamine receptor D4, Dopamine receptor D5, Dopaminergic, Enantiomer, Ergoline, Feces, Fibromyalgia, Food and Drug Administration, Hallucination, Headache, Histamine H1 receptor, Hyperalgesia, Hypersexuality, Insomnia, Intrinsic activity, Lightheadedness, Major depressive disorder, Movement disorders, Muscarinic acetylcholine receptor, Nausea, Nerve, Neurodegeneration, Neuron, Neurotransmitter, Orthostatic hypotension, Overeating, Parkinson's disease, Partial agonist, Peripheral edema, Piribedil, ..., Problem gambling, Proof of concept, Punding, Receptor (biochemistry), Restless legs syndrome, Riluzole, Ropinirole, Rotigotine, Sedation, Selective serotonin reuptake inhibitor, Sexual dysfunction, Side effect, Somnolence, Striatum, Substantia nigra, Synapse, Syncope (medicine), Talipexole, United States National Library of Medicine, Urine, Vomiting, Weight loss, 5-HT1A receptor, 5-HT1B receptor, 5-HT1D receptor, 5-HT2 receptor. Expand index (26 more) »
Adrenergic receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline).
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Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
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Alpha-1 adrenergic receptor
The alpha-1 (α1) adrenergic receptor is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G-protein.
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Alpha-2 adrenergic receptor
The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.
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Antidepressant
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
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Appetite
Appetite is the desire to eat food, sometimes due to hunger.
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Basal ganglia
The basal ganglia (or basal nuclei) is a group of subcortical nuclei, of varied origin, in the brains of vertebrates including humans, which are situated at the base of the forebrain.
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Bipolar disorder
Bipolar disorder, previously known as manic depression, is a mental disorder that causes periods of depression and periods of abnormally elevated mood.
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Cell (biology)
The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.
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Chirality (chemistry)
Chirality is a geometric property of some molecules and ions.
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Depression and Anxiety
Depression and Anxiety is a monthly peer-reviewed medical journal published by Wiley-Blackwell It is an official journal of the Anxiety and Depression Association of America and covers research on depressive and anxiety disorders.
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Dexpramipexole
Dexpramipexole (KNS-760704) is a drug that was investigated by Knopp Biosciences and Biogen Idec for the treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.
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Dissociation constant
In chemistry, biochemistry, and pharmacology, a dissociation constant (K_d) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.
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Dizziness
Dizziness is an impairment in spatial perception and stability.
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Dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
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Dopamine agonist
A dopamine receptor agonist is a compound that activates dopamine receptors.
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Dopamine receptor
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS).
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Dopamine receptor D1
Dopamine receptor D1, also known as DRD1, is a protein that in humans is encoded by the DRD1 gene.
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Dopamine receptor D2
Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.
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Dopamine receptor D3
Dopamine receptor D3 is a protein that in humans is encoded by the DRD3 gene.
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Dopamine receptor D4
The dopamine receptor D4 is a dopamine D2-like G protein-coupled receptor encoded by the gene on chromosome 11 at 11p15.5.
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Dopamine receptor D5
Dopamine receptor D5, also known as D1BR, is a protein that in humans is encoded by the DRD5 gene.
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Dopaminergic
Dopaminergic means "related to dopamine" (literally, "working on dopamine"), dopamine being a common neurotransmitter.
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Enantiomer
In chemistry, an enantiomer, also known as an optical isomer (and archaically termed antipode or optical antipode), is one of two stereoisomers that are mirror images of each other that are non-superposable (not identical), much as one's left and right hands are the same except for being reversed along one axis (the hands cannot be made to appear identical simply by reorientation).
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Ergoline
Ergoline derivatives comprise a diverse group of chemical compounds whose structural skeleton is the alkaloid ergoline.
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Feces
Feces (or faeces) are the solid or semisolid remains of the food that could not be digested in the small intestine.
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Fibromyalgia
Fibromyalgia (FM) is a medical condition characterised by chronic widespread pain and a heightened pain response to pressure.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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Hallucination
A hallucination is a perception in the absence of external stimulus that has qualities of real perception.
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Headache
Headache is the symptom of pain anywhere in the region of the head or neck.
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Histamine H1 receptor
The H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors.
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Hyperalgesia
Hyperalgesia (or; 'hyper' from Greek ὑπέρ (huper, “over”), '-algesia' from Greek algos, ἄλγος (pain)) is an increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves and can cause hypersensitivity to stimulus, stimuli which would normally not be cause for a pain reaction (ex/ eyes or brain having a painful reaction to daylight).
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Hypersexuality
Hypersexuality is a clinical diagnosis used by mental healthcare professionals to describe extremely frequent or suddenly increased libido.
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Insomnia
Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.
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Intrinsic activity
Intrinsic activity (IA) or efficacy refers to the relative ability of a drug-receptor complex to produce a maximum functional response.
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Lightheadedness
Lightheadedness is a common and typically unpleasant sensation of dizziness and/or a feeling that one may faint.
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Major depressive disorder
Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.
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Movement disorders
Movement disorders are clinical syndromes with either an excess of movement or a paucity of voluntary and involuntary movements, unrelated to weakness or spasticity.
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Muscarinic acetylcholine receptor
Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain neurons and other cells.
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Nausea
Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.
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Nerve
A nerve is an enclosed, cable-like bundle of axons (nerve fibers, the long and slender projections of neurons) in the peripheral nervous system.
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Neurodegeneration
Neurodegeneration is the progressive loss of structure or function of neurons, including death of neurons.
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Neuron
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
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Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
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Orthostatic hypotension
Orthostatic hypotension, also known as postural hypotension, occurs when a person's blood pressure falls when suddenly standing up from a lying or sitting position.
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Overeating
Overeating is the excess food in relation to the energy that an organism expends (or expels via excretion), leading to weight gaining and often obesity.
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Parkinson's disease
Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.
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Partial agonist
In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.
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Peripheral edema
Peripheral edema is edema (accumulation of fluid causing swelling) in tissues perfused by the peripheral vascular system, usually in the lower limbs.
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Piribedil
Piribedil (trade names Pronoran, Trivastal Retard, Trastal, Trivastan, Clarium and others) is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist.
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Problem gambling
Problem gambling (or ludomania, but usually referred to as "gambling addiction" or "compulsive gambling") is an urge to gamble continuously despite harmful negative consequences or a desire to stop.
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Proof of concept
Proof of concept (PoC) is a realization of a certain method or idea in order to demonstrate its feasibility, or a demonstration in principle with the aim of verifying that some concept or theory has practical potential.
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Punding
Punding is a term that was coined originally to describe complex prolonged, purposeless, and stereotyped behaviour in phenmetrazine and chronic amphetamine users, by Swedish forensic psychiatrist G. Rylander, in 1968.
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Receptor (biochemistry)
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
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Restless legs syndrome
Restless legs syndrome (RLS) is a disorder that causes a strong urge to move one's legs.
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Riluzole
Riluzole (marketed as Rilutek and Teglutik) is a drug used to treat amyotrophic lateral sclerosis.
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Ropinirole
Ropinirole (INN; trade names Requip, Repreve, Ronirol, Adartrel) is a dopamine agonist of the non-ergoline class of medications.
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Rotigotine
Rotigotine (Neupro) is a dopamine agonist of the non-ergoline class of medications indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS).
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Sedation
Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.
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Selective serotonin reuptake inhibitor
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.
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Sexual dysfunction
Sexual dysfunction (or sexual malfunction or sexual disorder) is difficulty experienced by an individual or a couple during any stage of a normal sexual activity, including physical pleasure, desire, preference, arousal or orgasm.
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Side effect
In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.
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Somnolence
Somnolence (alternatively "sleepiness" or "drowsiness") is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).
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Striatum
The striatum, or corpus striatum (also called the neostriatum and the striate nucleus) is a nucleus (a cluster of neurons) in the subcortical basal ganglia of the forebrain.
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Substantia nigra
The substantia nigra (SN) is a basal ganglia structure located in the midbrain that plays an important role in reward and movement.
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Synapse
In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target efferent cell.
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Syncope (medicine)
Syncope, also known as fainting, is a loss of consciousness and muscle strength characterized by a fast onset, short duration, and spontaneous recovery.
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Talipexole
Talipexole (B-HT920, Domnin) is a dopamine agonist that is marketed as a treatment for Parkinson's Disease in Japan by Boehringer Ingelheim; it was introduced in 1996.
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United States National Library of Medicine
The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library.
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Urine
Urine is a liquid by-product of metabolism in humans and in many animals.
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Vomiting
Vomiting, also known as emesis, puking, barfing, throwing up, among other terms, is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.
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Weight loss
Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, due to a mean loss of fluid, body fat or adipose tissue or lean mass, namely bone mineral deposits, muscle, tendon, and other connective tissue.
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5-HT1A receptor
The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).
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5-HT1B receptor
5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene.
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5-HT1D receptor
5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it.
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5-HT2 receptor
The 5-HT2 receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).
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Redirects here:
ATC code N04BC05, ATCvet code QN04BC05, Derinik, Mirapex, Pramip, Pramipexol, Pramipexole Dihydrochloride, Pramipexole dihydrochloride, Sifrol.
References
[1] https://en.wikipedia.org/wiki/Pramipexole
