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Metallibure

Index Metallibure

Metallibure (brand names Aimax, Suisynchron, Turisynchron; former developmental code names ICI-33828, AY-61122, NSC-69536), or methallibure is a nonsteroidal antigonadotropin that was introduced in 1973 and has been used in veterinary medicine to synchronize estrus. [1]

26 relations: Altrenogest, Anorexia (symptom), Antigonadotropin, Bifluranol, Cataract, Drug development, Estrous cycle, Europe, Gonadotropin, Hypothalamus, Lethargy, List of withdrawn drugs, Mechanism of action, Nausea, Nonsteroidal, Paroxypropione, Pituitary gland, Quadrosilan, Secretion, Side effect, Somnolence, Teratology, Toxicity, United States, Veterinary medicine, Vomiting.

Altrenogest

Altrenogest, sold under the brand names Regumate and Matrix, is a progestin of the 19-nortestosterone group which is widely used in veterinary medicine to suppress or synchronize estrus in horses and pigs.

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Anorexia (symptom)

Anorexia (from Ancient Greek ανορεξία: 'ἀν-' "without" + 'όρεξις', spelled 'órexis' meaning "appetite") is the decreased sensation of appetite.

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Antigonadotropin

An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

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Bifluranol

Bifluranol (brand name Prostarex; former developmental code name BX-341) is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that has been used as an antiandrogen in the United Kingdom in the treatment of benign prostatic hyperplasia.

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Cataract

A cataract is a clouding of the lens in the eye which leads to a decrease in vision.

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Drug development

Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.

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Estrous cycle

The estrous cycle or oestrus cycle (derived from Latin oestrus 'frenzy', originally from Greek οἶστρος oîstros 'gadfly') is the recurring physiological changes that are induced by reproductive hormones in most mammalian therian females.

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Europe

Europe is a continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere.

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Gonadotropin

Gonadotropins are glycoprotein polypeptide hormones secreted by gonadotrope cells of the anterior pituitary of vertebrates.

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Hypothalamus

The hypothalamus(from Greek ὑπό, "under" and θάλαμος, thalamus) is a portion of the brain that contains a number of small nuclei with a variety of functions.

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Lethargy

Lethargy is a state of tiredness, weariness, fatigue, or lack of energy.

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List of withdrawn drugs

Drugs or medicines may be withdrawn from commercial markets because of risks to patients, but also because of commercial reasons (e.g. lack of demand and relatively high production costs).

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Mechanism of action

In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.

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Nausea

Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.

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Nonsteroidal

Nonsteroidal is a term which is used to describe a compound that is not a steroid.

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Paroxypropione

Paroxypropione is a synthetic nonsteroidal estrogen which has been used medically as an antigonadotropin in Spain and Italy but appears to no longer be marketed.

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Pituitary gland

An explanation of the development of the pituitary gland (Hypophysis cerebri) & the congenital anomalies. In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland about the size of a pea and weighing in humans.

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Quadrosilan

Quadrosilan (brand name Cisobitan; former developmental code name KABI-1774) is a synthetic nonsteroidal estrogen that was developed in the 1970s and that is or has been used as an antigonadotropic agent in the treatment of prostate cancer.

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Secretion

Secretion is the movement of material from one point to another, e.g. secreted chemical substance from a cell or gland.

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Side effect

In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.

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Somnolence

Somnolence (alternatively "sleepiness" or "drowsiness") is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).

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Teratology

Teratology is the study of abnormalities of physiological development.

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Toxicity

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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Veterinary medicine

Veterinary medicine is the branch of medicine that deals with the prevention, diagnosis and treatment of disease, disorder and injury in non-human animals.

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Vomiting

Vomiting, also known as emesis, puking, barfing, throwing up, among other terms, is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.

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Redirects here:

AY 61,122, AY 61122, AY-61,122, AY-61122, AY61,122, AY61122, Aimax, ICI 33,828, ICI 33828, ICI-33,828, ICI-33828, ICI33,828, ICI33828, Metallibur, Methallibur, Methallibure, NSC 69,536, NSC 69536, NSC-69,536, NSC-69536, NSC69,536, NSC69536, Suisynchron, Turisynchron.

References

[1] https://en.wikipedia.org/wiki/Metallibure

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