In organic chemistry, acetyl is a moiety, the acyl with chemical formula CH3CO.
Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism.
Acetylation (or in IUPAC nomenclature ethanoylation) describes a reaction that introduces an acetyl functional group into a chemical compound.
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence.
In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes.
Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl-CoA to form ε-N-acetyllysine.
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups (O.
Lysine (symbol Lys or K) is an α-amino acid that is used in the biosynthesis of proteins.
In proteins, the amino acid residue lysine can be methylated once, twice or thrice on its terminal sidechain ammonium group.
A nucleosome is a basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound in sequence around eight histone protein cores.
Pivagabine (INN; brand name Tonerg), also known as N-pivaloyl-γ-aminobutyric acid or N-pivaloyl-GABA, is an antidepressant and anxiolytic drug which was introduced in Italy in 1997 for the treatment of depressive and maladaptive syndromes.
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.