Table of Contents
101 relations: Acidosis, ACTH stimulation test, Addison's disease, Adrenal cortex, Adrenal ferredoxin, Adrenal gland, Adrenal insufficiency, Adrenocortical adenoma, Adrenocorticotropic hormone, Aldosterone synthase, Aldosterone-to-renin ratio, Angiotensin, Angiotensin-converting enzyme, Atrial natriuretic peptide, Atrium (heart), Ball-and-stick model, Baroreceptor, Biological half-life, Blood plasma, Blood pressure, Blood volume, Calcium, Calcium channel, Calcium channel blocker, Cambridge Crystallographic Data Centre, Cambridge Structural Database, Cardiovascular disease, Cell membrane, Channel-inducing factor 4, Cholesterol, Collecting duct system, Corticosteroid, Corticosterone, Cortisol, Crystallography, CYP17A1, Cytochrome, Day, Dentate gyrus, Deoxycorticosterone, Distal convoluted tubule, Edema, Enoxolone, Epithelial sodium channel, Fludrocortisone, Glomerular filtration rate, Glossary of biology, Heart, Homeostasis, Hyperaldosteronism, ... Expand index (51 more) »
- GPER agonists
- Mineralocorticoids
- Steroid hormones
Acidosis
Acidosis is a biological process producing hydrogen ions and increasing their concentration in blood or body fluids.
ACTH stimulation test
The ACTH test (also called the cosyntropin, tetracosactide, or Synacthen test) is a medical test usually requested and interpreted by endocrinologists to assess the functioning of the adrenal glands' stress response by measuring the adrenal response to adrenocorticotropic hormone (ACTH; corticotropin) or another corticotropic agent such as tetracosactide (cosyntropin, tetracosactrin; Synacthen) or alsactide (Synchrodyn).
See Aldosterone and ACTH stimulation test
Addison's disease
Addison's disease, also known as primary adrenal insufficiency, is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal glands (adrenal cortex), causing adrenal insufficiency.
See Aldosterone and Addison's disease
Adrenal cortex
The adrenal cortex is the outer region and also the largest part of the adrenal gland.
See Aldosterone and Adrenal cortex
Adrenal ferredoxin
Adrenal ferredoxin (also adrenodoxin (ADX), adrenodoxin, mitochondrial, hepatoredoxin, ferredoxin-1 (FDX1)) is a protein that in humans is encoded by the FDX1 gene.
See Aldosterone and Adrenal ferredoxin
Adrenal gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.
See Aldosterone and Adrenal gland
Adrenal insufficiency
Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones.
See Aldosterone and Adrenal insufficiency
Adrenocortical adenoma
An adrenocortical adenoma or adrenal adenoma is commonly described as a benign neoplasm emerging from the cells that comprise the adrenal cortex.
See Aldosterone and Adrenocortical adenoma
Adrenocorticotropic hormone
Adrenocorticotropic hormone (ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland.
See Aldosterone and Adrenocorticotropic hormone
Aldosterone synthase
Aldosterone synthase, also called steroid 18-hydroxylase, corticosterone 18-monooxygenase or P450C18, is a steroid hydroxylase cytochrome P450 enzyme involved in the biosynthesis of the mineralocorticoid aldosterone and other steroids.
See Aldosterone and Aldosterone synthase
Aldosterone-to-renin ratio
Aldosterone-to-renin ratio (ARR) is the mass concentration of aldosterone divided by the plasma renin activity or by serum renin concentration in blood.
See Aldosterone and Aldosterone-to-renin ratio
Angiotensin
Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure.
See Aldosterone and Angiotensin
Angiotensin-converting enzyme
Angiotensin-converting enzyme, or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body.
See Aldosterone and Angiotensin-converting enzyme
Atrial natriuretic peptide
Atrial Natriuretic Peptide (ANP) or atrial natriuretic factor (ANF) is a natriuretic peptide hormone secreted from the cardiac atria that in humans is encoded by the NPPA gene.
See Aldosterone and Atrial natriuretic peptide
Atrium (heart)
The atrium (entry hall;: atria) is one of the two upper chambers in the heart that receives blood from the circulatory system.
See Aldosterone and Atrium (heart)
Ball-and-stick model
In chemistry, the ball-and-stick model is a molecular model of a chemical substance which displays both the three-dimensional position of the atoms and the bonds between them.
See Aldosterone and Ball-and-stick model
Baroreceptor
Baroreceptors (or archaically, pressoreceptors) are sensors located in the carotid sinus (at the bifurcation of common carotid artery into external and internal carotids) and in the aortic arch.
See Aldosterone and Baroreceptor
Biological half-life
Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (Cmax) to half of Cmax in the blood plasma.
See Aldosterone and Biological half-life
Blood plasma
Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but which contains proteins and other constituents of whole blood in suspension.
See Aldosterone and Blood plasma
Blood pressure
Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels.
See Aldosterone and Blood pressure
Blood volume
Blood volume (volemia) is the volume of blood (blood cells and plasma) in the circulatory system of any individual.
See Aldosterone and Blood volume
Calcium
Calcium is a chemical element; it has symbol Ca and atomic number 20.
Calcium channel
A calcium channel is an ion channel which shows selective permeability to calcium ions.
See Aldosterone and Calcium channel
Calcium channel blocker
Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are a group of medications that disrupt the movement of calcium through calcium channels.
See Aldosterone and Calcium channel blocker
Cambridge Crystallographic Data Centre
The Cambridge Crystallographic Data Centre (CCDC) is a non-profit organisation based in Cambridge, England.
See Aldosterone and Cambridge Crystallographic Data Centre
Cambridge Structural Database
The Cambridge Structural Database (CSD) is both a repository and a validated and curated resource for the three-dimensional structural data of molecules generally containing at least carbon and hydrogen, comprising a wide range of organic, metal-organic and organometallic molecules.
See Aldosterone and Cambridge Structural Database
Cardiovascular disease
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels.
See Aldosterone and Cardiovascular disease
Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space).
See Aldosterone and Cell membrane
Channel-inducing factor 4
Channel-inducing factor is a regulatory protein for aldosterone receptors.
See Aldosterone and Channel-inducing factor 4
Cholesterol
Cholesterol is the principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
See Aldosterone and Cholesterol
Collecting duct system
The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.
See Aldosterone and Collecting duct system
Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Aldosterone and Corticosteroid are steroid hormones.
See Aldosterone and Corticosteroid
Corticosterone
Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroxyprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. Aldosterone and Corticosterone are Pregnanes.
See Aldosterone and Corticosterone
Cortisol
Cortisol is a steroid hormone in the glucocorticoid class of hormones and a stress hormone. Aldosterone and Cortisol are Pregnanes and steroid hormones.
Crystallography
Crystallography is the branch of science devoted to the study of molecular and crystalline structure and properties.
See Aldosterone and Crystallography
CYP17A1
Cytochrome P450 17A1 (steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is encoded by the CYP17A1 gene on chromosome 10.
Cytochrome
Cytochromes are redox-active proteins containing a heme, with a central iron (Fe) atom at its core, as a cofactor.
See Aldosterone and Cytochrome
Day
A day is the time period of a full rotation of the Earth with respect to the Sun.
Dentate gyrus
The dentate gyrus (DG) is part of the hippocampal formation in the temporal lobe of the brain, which also includes the hippocampus and the subiculum.
See Aldosterone and Dentate gyrus
Deoxycorticosterone
Deoxycorticosterone (DOC), or desoxycorticosterone, may refer to. Aldosterone and Deoxycorticosterone are Pregnanes.
See Aldosterone and Deoxycorticosterone
Distal convoluted tubule
The distal convoluted tubule (DCT) is a portion of kidney nephron between the loop of Henle and the collecting tubule.
See Aldosterone and Distal convoluted tubule
Edema
Edema (AmE), also spelled oedema (BrE), and also known as fluid retention, dropsy, hydropsy and swelling, is the build-up of fluid in the body's tissue.
Enoxolone
Enoxolone (INN, BAN; also known as glycyrrhetinic acid or glycyrrhetic acid) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice. Aldosterone and Enoxolone are Enones.
Epithelial sodium channel
The epithelial sodium channel (ENaC), (also known as amiloride-sensitive sodium channel) is a membrane-bound ion channel that is selectively permeable to sodium ions.
See Aldosterone and Epithelial sodium channel
Fludrocortisone
Fludrocortisone, sold under the brand name Florinef, among others, is a corticosteroid used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency. Aldosterone and Fludrocortisone are mineralocorticoids and Pregnanes.
See Aldosterone and Fludrocortisone
Glomerular filtration rate
Renal functions include maintaining an acid–base balance; regulating fluid balance; regulating sodium, potassium, and other electrolytes; clearing toxins; absorption of glucose, amino acids, and other small molecules; regulation of blood pressure; production of various hormones, such as erythropoietin; and activation of vitamin D.
See Aldosterone and Glomerular filtration rate
Glossary of biology
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.
See Aldosterone and Glossary of biology
Heart
The heart is a muscular organ found in most animals.
Homeostasis
In biology, homeostasis (British also homoeostasis) is the state of steady internal physical and chemical conditions maintained by living systems.
See Aldosterone and Homeostasis
Hyperaldosteronism
Hyperaldosteronism is a medical condition wherein too much aldosterone is produced.
See Aldosterone and Hyperaldosteronism
Hypertension
Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.
See Aldosterone and Hypertension
Hypoaldosteronism
Hypoaldosteronism is an endocrinological disorder characterized by decreased levels of the hormone aldosterone.
See Aldosterone and Hypoaldosteronism
Hypokalemia
Hypokalemia is a low level of potassium (K+) in the blood serum.
See Aldosterone and Hypokalemia
Inverse function
In mathematics, the inverse function of a function (also called the inverse of) is a function that undoes the operation of.
See Aldosterone and Inverse function
James Francis Tait
James Francis Tait (1926-2014) was an English physicist and endocrinologist.
See Aldosterone and James Francis Tait
Journal of the American Chemical Society
The Journal of the American Chemical Society (also known as JACS) is a weekly peer-reviewed scientific journal that was established in 1879 by the American Chemical Society.
See Aldosterone and Journal of the American Chemical Society
Juxtaglomerular apparatus
The juxtaglomerular apparatus (also known as the juxtaglomerular complex) is a structure in the kidney that regulates the function of each nephron, the functional units of the kidney.
See Aldosterone and Juxtaglomerular apparatus
Kidney
In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.
Kidney disease
Kidney disease, or renal disease, technically referred to as nephropathy, is damage to or disease of a kidney.
See Aldosterone and Kidney disease
Lipid
Lipids are a broad group of organic compounds which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others.
Liquorice
Liquorice (British English) or licorice (American English) is the common name of Glycyrrhiza glabra, a flowering plant of the bean family Fabaceae, from the root of which a sweet, aromatic flavouring is extracted. The liquorice plant is an herbaceous perennial legume native to West Asia, North Africa, and Southern Europe.
Lisinopril
Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks.
See Aldosterone and Lisinopril
Mechanoreceptor
A mechanoreceptor, also called mechanoceptor, is a sensory receptor that responds to mechanical pressure or distortion.
See Aldosterone and Mechanoreceptor
Mineralocorticoid
Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones. Aldosterone and Mineralocorticoid are mineralocorticoids.
See Aldosterone and Mineralocorticoid
Mineralocorticoid receptor
The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2.
See Aldosterone and Mineralocorticoid receptor
Mineralocorticoid receptor antagonist
A mineralocorticoid receptor antagonist (MRA or MCRA) or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.
See Aldosterone and Mineralocorticoid receptor antagonist
Mitochondrion
A mitochondrion is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi.
See Aldosterone and Mitochondrion
Nephron
The nephron is the minute or microscopic structural and functional unit of the kidney.
Pharmacological Reviews
Pharmacological Reviews is a quarterly peer-reviewed scientific journal publishing review articles on all aspects of pharmacology and related topics.
See Aldosterone and Pharmacological Reviews
Plasma renin activity
Plasma renin activity (PRA), also known as the renin (active) assay or random plasma renin, is a measure of the activity of the plasma enzyme renin, which plays a major role in the body's regulation of blood pressure, thirst, and urine output.
See Aldosterone and Plasma renin activity
Potassium
Potassium is a chemical element; it has symbol K (from Neo-Latin kalium) and atomic number19.
Potassium-sparing diuretic
Potassium-sparing diuretics or antikaliuretics refer to drugs that cause diuresis without causing potassium loss in the urine.
See Aldosterone and Potassium-sparing diuretic
Primary aldosteronism
Primary aldosteronism (PA), also known as primary hyperaldosteronism, refers to the excess production of the hormone aldosterone from the adrenal glands, resulting in low renin levels and high blood pressure.
See Aldosterone and Primary aldosteronism
Protein subunit
In structural biology, a protein subunit is a polypeptide chain or single protein molecule that assembles (or "coassembles") with others to form a protein complex.
See Aldosterone and Protein subunit
Redox
Redox (reduction–oxidation or oxidation–reduction) is a type of chemical reaction in which the oxidation states of the reactants change.
Renin
Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that increases the volume of extracellular fluid (blood plasma, lymph and interstitial fluid) and causes arterial vasoconstriction.
Renin–angiotensin system
The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure, fluid and electrolyte balance, and systemic vascular resistance.
See Aldosterone and Renin–angiotensin system
Response element
Response elements are short sequences of DNA within a gene promoter or enhancer region that are able to bind specific transcription factors and regulate transcription of genes.
See Aldosterone and Response element
RSC Advances
RSC Advances is an online-only peer-reviewed scientific journal covering research on all aspects of the chemical sciences.
See Aldosterone and RSC Advances
SGK
Serine/threonine-protein kinases SGK represent a kinase subfamily with orthologs found across animal clades and in yeast (compare). In most vertebrates, including humans, there are three isoforms encoded by the genes SGK1, SGK2, and SGK3.
Shelley Hurwitz
Shelley Hurwitz is an American biostatistician.
See Aldosterone and Shelley Hurwitz
Skeletal formula
The skeletal formula, line-angle formula, bond-line formula or shorthand formula of an organic compound is a type of molecular structural formula that serves as a shorthand representation of a molecule's bonding and some details of its molecular geometry.
See Aldosterone and Skeletal formula
Sodium
Sodium is a chemical element; it has symbol Na (from Neo-Latin natrium) and atomic number 11.
Sodium-chloride symporter
The sodium-chloride symporter (also known as Na+-Cl− cotransporter, NCC or NCCT, or as the thiazide-sensitive Na+-Cl− cotransporter or TSC) is a cotransporter in the kidney which has the function of reabsorbing sodium and chloride ions from the tubular fluid into the cells of the distal convoluted tubule of the nephron.
See Aldosterone and Sodium-chloride symporter
Sodium–potassium pump
The sodium–potassium pump (sodium–potassium adenosine triphosphatase, also known as -ATPase, pump, or sodium–potassium ATPase) is an enzyme (an electrogenic transmembrane ATPase) found in the membrane of all animal cells.
See Aldosterone and Sodium–potassium pump
Spirolactone
Spirolactones are a class of functional group in organic chemistry featuring a cyclic ester attached spiro to another ring system. Aldosterone and Spirolactone are Pregnanes.
See Aldosterone and Spirolactone
Spironolactone
Spironolactone, sold under the brand name Aldactone among others, is a diuretic medication primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. Aldosterone and Spironolactone are Pregnanes.
See Aldosterone and Spironolactone
Steroid
A steroid is an organic compound with four fused rings (designated A, B, C, and D) arranged in a specific molecular configuration.
Steroid 11β-hydroxylase
Steroid 11β-hydroxylase, also known as steroid 11β-monooxygenase, is a steroid hydroxylase found in the zona glomerulosa and zona fasciculata of the adrenal cortex.
See Aldosterone and Steroid 11β-hydroxylase
Steroid hormone
A steroid hormone is a steroid that acts as a hormone. Aldosterone and steroid hormone are steroid hormones.
See Aldosterone and Steroid hormone
Steroid hormone receptor
Steroid hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells.
See Aldosterone and Steroid hormone receptor
Surgical stress
Surgical stress is the systemic response to surgical injury and is characterized by activation of the sympathetic nervous system, endocrine responses as well as immunological and haematological changes.
See Aldosterone and Surgical stress
Sylvia Agnes Sophia Tait
Sylvia Agnes Sophia Tait (8 January 1917 – 28 February 2003) (née Wardropper, known as Sylvia Simpson from 1941 to 1956) was an English biochemist and endocrinologist.
See Aldosterone and Sylvia Agnes Sophia Tait
Sympathetic nervous system
The sympathetic nervous system (SNS) is one of the three divisions of the autonomic nervous system, the others being the parasympathetic nervous system and the enteric nervous system.
See Aldosterone and Sympathetic nervous system
Tadeusz Reichstein
Tadeusz Reichstein (20 July 1897 – 1 August 1996), also known as Tadeus Reichstein, was a Polish-Swiss chemist and the Nobel Prize in Physiology or Medicine laureate (1950), which was awarded for his work on the isolation of cortisone.
See Aldosterone and Tadeusz Reichstein
Transcription (biology)
Transcription is the process of copying a segment of DNA into RNA.
See Aldosterone and Transcription (biology)
Voltage-gated calcium channel
Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the calcium ion Ca2+.
See Aldosterone and Voltage-gated calcium channel
Zona fasciculata
The zona fasciculata (sometimes, fascicular or fasciculate zone) constitutes the middle and also the widest zone of the adrenal cortex, sitting directly beneath the zona glomerulosa.
See Aldosterone and Zona fasciculata
Zona glomerulosa
The zona glomerulosa (sometimes, glomerular zone) of the adrenal gland is the most superficial layer of the adrenal cortex, lying directly beneath the renal capsule.
See Aldosterone and Zona glomerulosa
11β-Hydroxysteroid dehydrogenase
11β-Hydroxysteroid dehydrogenase (HSD-11β or 11β-HSD) enzymes catalyze the conversion of inert 11 keto-products (cortisone) to active cortisol, or vice versa, thus regulating the access of glucocorticoids to the steroid receptors.
See Aldosterone and 11β-Hydroxysteroid dehydrogenase
21-Hydroxylase
Steroid 21-hydroxylase is a protein that in humans is encoded by the CYP21A2 gene.
See Aldosterone and 21-Hydroxylase
See also
GPER agonists
- 2-Methoxyestradiol
- Afimoxifene
- Aldosterone
- Atrazine
- Bisphenol A
- Chlordecone
- DDT
- Daidzein
- Diarylpropionitrile
- Equol
- Estradiol
- Estradiol (medication)
- Ethinylestradiol
- Fulvestrant
- Genistein
- Hydroxytyrosol
- Niacin
- Nicotinamide
- Nonylphenol
- Oleuropein
- Propylpyrazoletriol
- Quercetin
- Raloxifene
- Resveratrol
- Tamoxifen
- Tectoridin
Mineralocorticoids
- 11β-Hydroxyprogesterone
- 11-Dehydrocorticosterone
- 11-Deoxycorticosterone
- 11-Deoxycortisol
- 18-Hydroxy-11-deoxycorticosterone
- 18-Oxocortisol
- 19-Norprogesterone
- 5α-Dihydroaldosterone
- Aldosterone
- Corticosteroid esters
- Cortifen
- Cortisone acetate
- Desoxycorticosterone acetate
- Desoxycorticosterone pivalate
- Fludrocortisone
- Hydrocortisone
- Hydrocortisone hemisuccinate
- Membrane mineralocorticoid receptor
- Mineralocorticoid
- Mometasone
- Prednazate
- Prednazoline
- Prednisolamate
- Prednisolone
- Prednisone
Steroid hormones
- 11β-Hydroxyandrostenedione
- 11-Deoxycorticosterone
- 11-Deoxycortisol
- 11-Ketodihydrotestosterone
- 11-Ketotestosterone
- 15α-Hydroxy-DHEA sulfate
- 16α-Hydroxy-DHEA sulfate
- 16α-Hydroxyandrostenedione
- 16α-Hydroxyprogesterone
- 18-Hydroxy-11-deoxycorticosterone
- 2-Hydroxyestradiol
- 20α-Dihydroprogesterone
- 20β-Dihydroprogesterone
- 4-Methoxyestradiol
- 4-Methoxyestrone
- Adrenosterone
- Aldosterone
- Androgen conjugate
- Androstanedione
- Androsterone
- Catechol estrogen
- Corticosteroid
- Corticosteroids
- Cortisol
- Dafachronic acid
- Estrogen conjugate
- Etiocholanedione
- H295R
- Pregnenolone
- Progesterone
- Steroid hormone
- Steroid sulfate
- Testosterone
- Tetrahydrocorticosterone
References
Also known as ATC code H02AA01, ATCvet code QH02AA01, Adrenoglomerulotropin, Aldosteron, Receptors, aldosterone.