Table of Contents
41 relations: Adrenal cortex, Adrenocorticotropic hormone, Aldosterone, Androstenedione, Blood pressure, Cholesterol, Chromosome 8, Corticosterone, Cortisol, Cytochrome P450, Electrolyte, Estradiol, Gene, Glucocorticoid remediable aldosteronism, Heart failure, Homology (biology), Hydroxylation, Hypertension, Hypoaldosteronism, Hypokalemia, Kidney, Lipid, Mineralocorticoid receptor, Monooxygenase, Pregnenolone, Progesterone, Renin, Renin–angiotensin system, Steroid, Steroid 11β-hydroxylase, Steroidogenic enzyme, Testosterone, Transcription factor, Zona glomerulosa, 11-Deoxycorticosterone, 11-Deoxycortisol, 11β-Hydroxyprogesterone, 11β-Hydroxytestosterone, 18-Hydroxy-11-deoxycorticosterone, 18-Hydroxycorticosterone, 21-Hydroxypregnenolone.
Adrenal cortex
The adrenal cortex is the outer region and also the largest part of the adrenal gland.
See Aldosterone synthase and Adrenal cortex
Adrenocorticotropic hormone
Adrenocorticotropic hormone (ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland.
See Aldosterone synthase and Adrenocorticotropic hormone
Aldosterone
Aldosterone is the main mineralocorticoid steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
See Aldosterone synthase and Aldosterone
Androstenedione
Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).
See Aldosterone synthase and Androstenedione
Blood pressure
Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels.
See Aldosterone synthase and Blood pressure
Cholesterol
Cholesterol is the principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
See Aldosterone synthase and Cholesterol
Chromosome 8
Chromosome 8 is one of the 23 pairs of chromosomes in humans. Aldosterone synthase and chromosome 8 are genes on human chromosome 8.
See Aldosterone synthase and Chromosome 8
Corticosterone
Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroxyprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
See Aldosterone synthase and Corticosterone
Cortisol
Cortisol is a steroid hormone in the glucocorticoid class of hormones and a stress hormone.
See Aldosterone synthase and Cortisol
Cytochrome P450
Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases.
See Aldosterone synthase and Cytochrome P450
Electrolyte
An electrolyte is a medium containing ions that are electrically conductive through the movement of those ions, but not conducting electrons.
See Aldosterone synthase and Electrolyte
Estradiol
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.
See Aldosterone synthase and Estradiol
Gene
In biology, the word gene has two meanings.
See Aldosterone synthase and Gene
Glucocorticoid remediable aldosteronism
Glucocorticoid remediable aldosteronism also describable as aldosterone synthase hyperactivity, is an autosomal dominant disorder in which the increase in aldosterone secretion produced by ACTH is no longer transient.
See Aldosterone synthase and Glucocorticoid remediable aldosteronism
Heart failure
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood.
See Aldosterone synthase and Heart failure
Homology (biology)
In biology, homology is similarity due to shared ancestry between a pair of structures or genes in different taxa.
See Aldosterone synthase and Homology (biology)
Hydroxylation
In chemistry, hydroxylation can refer to.
See Aldosterone synthase and Hydroxylation
Hypertension
Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.
See Aldosterone synthase and Hypertension
Hypoaldosteronism
Hypoaldosteronism is an endocrinological disorder characterized by decreased levels of the hormone aldosterone.
See Aldosterone synthase and Hypoaldosteronism
Hypokalemia
Hypokalemia is a low level of potassium (K+) in the blood serum.
See Aldosterone synthase and Hypokalemia
Kidney
In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.
See Aldosterone synthase and Kidney
Lipid
Lipids are a broad group of organic compounds which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others.
See Aldosterone synthase and Lipid
Mineralocorticoid receptor
The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2.
See Aldosterone synthase and Mineralocorticoid receptor
Monooxygenase
Monooxygenases are enzymes that incorporate one hydroxyl group (−OH) into substrates in many metabolic pathways.
See Aldosterone synthase and Monooxygenase
Pregnenolone
Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids.
See Aldosterone synthase and Pregnenolone
Progesterone
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.
See Aldosterone synthase and Progesterone
Renin
Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that increases the volume of extracellular fluid (blood plasma, lymph and interstitial fluid) and causes arterial vasoconstriction.
See Aldosterone synthase and Renin
Renin–angiotensin system
The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure, fluid and electrolyte balance, and systemic vascular resistance.
See Aldosterone synthase and Renin–angiotensin system
Steroid
A steroid is an organic compound with four fused rings (designated A, B, C, and D) arranged in a specific molecular configuration.
See Aldosterone synthase and Steroid
Steroid 11β-hydroxylase
Steroid 11β-hydroxylase, also known as steroid 11β-monooxygenase, is a steroid hydroxylase found in the zona glomerulosa and zona fasciculata of the adrenal cortex. Aldosterone synthase and steroid 11β-hydroxylase are genes on human chromosome 8.
See Aldosterone synthase and Steroid 11β-hydroxylase
Steroidogenic enzyme
Steroidogenic enzymes are enzymes that are involved in steroidogenesis and steroid biosynthesis.
See Aldosterone synthase and Steroidogenic enzyme
Testosterone
Testosterone is the primary male sex hormone and androgen in males.
See Aldosterone synthase and Testosterone
Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
See Aldosterone synthase and Transcription factor
Zona glomerulosa
The zona glomerulosa (sometimes, glomerular zone) of the adrenal gland is the most superficial layer of the adrenal cortex, lying directly beneath the renal capsule.
See Aldosterone synthase and Zona glomerulosa
11-Deoxycorticosterone
11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone, and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.
See Aldosterone synthase and 11-Deoxycorticosterone
11-Deoxycortisol
11-Deoxycortisol, also known as cortodoxone (INN), cortexolone as well as 17α,21-dihydroxyprogesterone or 17α,21-dihydroxypregn-4-ene-3,20-dione, is an endogenous glucocorticoid steroid hormone, and a metabolic intermediate toward cortisol.
See Aldosterone synthase and 11-Deoxycortisol
11β-Hydroxyprogesterone
11β-Hydroxyprogesterone (11β-OHP), also known as 21-deoxycorticosterone, as well as 11β-hydroxypregn-4-ene-3,20-dione, is a naturally occurring, endogenous steroid and derivative of progesterone.
See Aldosterone synthase and 11β-Hydroxyprogesterone
11β-Hydroxytestosterone
11β-Hydroxytestosterone is an endogenous steroid, a metabolite of testosterone.
See Aldosterone synthase and 11β-Hydroxytestosterone
18-Hydroxy-11-deoxycorticosterone
18-Hydroxy-11-deoxycorticosterone (also known as 18-OH-DOC, 18,21-dihydroxyprogesterone, and 18,21-dihydroxypregn-4-ene-3,20-dione) is an endogenous steroid and a mineralocorticoid.
See Aldosterone synthase and 18-Hydroxy-11-deoxycorticosterone
18-Hydroxycorticosterone
18-Hydroxycorticosterone is an endogenous steroid.
See Aldosterone synthase and 18-Hydroxycorticosterone
21-Hydroxypregnenolone
21-Hydroxypregnenolone, also known as prebediolone, as well as 3β,21-dihydroxypregn-5-en-20-one, is a naturally occurring and endogenous pregnane steroid, and an intermediate in the biosynthesis of 11-deoxycorticosterone (21-hydroxyprogesterone), corticosterone (11β,21-dihydroxyprogesterone), and other corticosteroids.
See Aldosterone synthase and 21-Hydroxypregnenolone
References
Also known as 18-Hydroxylase, 18-Hydroxylase deficiency, 18-hydroxylation, Aldosterone synthase deficiency, Aldosterone synthetase deficiency, CYP11B2, CYP11B2 (gene).