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38 relations: Alkylating antineoplastic agent, Antibody-dependent cell-mediated cytotoxicity, Aspergillosis, Autoimmune disease, Bayer, CD52, Center for Drug Evaluation and Research, Chronic lymphocytic leukemia, Complementarity-determining region, Cutaneous T cell lymphoma, Cytomegalovirus, Fludarabine, Food and Drug Administration, Genzyme, Graft-versus-host disease, Greg Winter, Health Canada, Hematopoietic stem cell transplantation, Herman Waldmann, Immunoglobulin G, Interferon beta-1a, Intravenous therapy, Islet cell transplantation, Kidney transplantation, Lymphocyte, Medication, Monoclonal antibody, Multiple sclerosis, New Scientist, Non-Hodgkin lymphoma, Off-label use, Opportunistic infection, Regulatory T cell, Sanofi, Stem cell, Subtypes of HIV, The Wall Street Journal, University of Cambridge.
Alkylating antineoplastic agent
An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group (CnH2n+1) to DNA.
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Antibody-dependent cell-mediated cytotoxicity
The antibody-dependent cell-mediated cytotoxicity (ADCC), also referred to as antibody-dependent cellular cytotoxicity, is a mechanism of cell-mediated immune defense whereby an effector cell of the immune system actively lyses a target cell, whose membrane-surface antigens have been bound by specific antibodies.
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Aspergillosis
Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus.
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Autoimmune disease
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.
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Bayer
Bayer AG is a German multinational, pharmaceutical and life sciences company.
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CD52
CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.
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Center for Drug Evaluation and Research
The Center for Drug Evaluation and Research (CDER, pronounced "see'-der") is a division of the U.S. Food and Drug Administration (FDA) that monitors most drugs as defined in the Food, Drug, and Cosmetic Act.
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Chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell).
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Complementarity-determining region
Complementarity-determining regions (CDRs) are part of the variable chains in immunoglobulins (antibodies) and T cell receptors, generated by B-cells and T-cells respectively, where these molecules bind to their specific antigen.
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Cutaneous T cell lymphoma
Cutaneous T cell lymphoma (CTCL) is a class of non-Hodgkin lymphoma, which is a type of cancer of the immune system.
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Cytomegalovirus
Cytomegalovirus (CMV) (from the Greek cyto-, "cell", and megalo-, "large") is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Betaherpesvirinae.
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Fludarabine
Fludarabine, sold under the brand name Fludara among others, is a chemotherapy medication used in the treatment of leukemia and lymphoma.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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Genzyme
Sanofi Genzyme is an American biotechnology company based in Cambridge, Massachusetts.
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Graft-versus-host disease
Graft-versus-host disease (GvHD) is a medical complication following the receipt of transplanted tissue from a genetically different person.
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Greg Winter
Sir Gregory Paul Winter (born 14 April 1951) is a British biochemist, a pioneer of therapeutic monoclonal antibodies.
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Health Canada
Health Canada (Santé Canada) is the department of the government of Canada with responsibility for national public health.
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Hematopoietic stem cell transplantation
Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood.
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Herman Waldmann
Herman Waldmann FRS FMedSci (born 27 February 1945) is a British immunologist known for his work on therapeutic monoclonal antibodies.
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Immunoglobulin G
Immunoglobulin G (IgG) is a type of antibody.
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Interferon beta-1a
Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS).
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Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
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Islet cell transplantation
Islet transplantation is the transplantation of isolated islets from a donor pancreas into another person.
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Kidney transplantation
Kidney transplantation or renal transplantation is the organ transplant of a kidney into a patient with end-stage renal disease.
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Lymphocyte
A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.
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Medication
A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.
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Monoclonal antibody
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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New Scientist
New Scientist, first published on 22 November 1956, is a weekly, English-language magazine that covers all aspects of science and technology.
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Non-Hodgkin lymphoma
Non-Hodgkin lymphoma (NHL) is a group of blood cancers that includes all types of lymphoma except Hodgkin's lymphomas.
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Off-label use
Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration.
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Opportunistic infection
An opportunistic infection is an infection caused by pathogens (bacteria, viruses, fungi, or protozoa) that take advantage of an opportunity not normally available, such as a host with a weakened immune system, an altered microbiota (such as a disrupted gut microbiota), or breached integumentary barriers.
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Regulatory T cell
The regulatory T cells (Tregs), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease.
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Sanofi
Sanofi S.A. is a French multinational pharmaceutical company headquartered in Gentilly, France, as of 2013 the world's fifth-largest by prescription sales.
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Stem cell
Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.
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Subtypes of HIV
One of the obstacles to treatment of the human immunodeficiency virus is its high genetic variability.
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The Wall Street Journal
The Wall Street Journal is a U.S. business-focused, English-language international daily newspaper based in New York City.
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University of Cambridge
The University of Cambridge (informally Cambridge University)The corporate title of the university is The Chancellor, Masters, and Scholars of the University of Cambridge.
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Redirects here:
ATC code L01XC04, ATCvet code QL01XC04, CAMPATH-1H, Campath, Campath-1H, Lemtrada, MabCampath.
References
[1] https://en.wikipedia.org/wiki/Alemtuzumab
